The purpose of this paper is to present a novel drug for treating immune-mediated diseases in dogs. Mycophenolate mofetil is one of the modern immunosuppressive drugs used in transplantology and in the treatment of immune-mediated diseases in humans. Its immunosuppressive activity depends on...

Objective: To report synovial fluid lactate concentrations in normal and pathological canine joints. Study design: Controlled, prospective study. Methods: Lactate was measured in synovial fluid using a hand-held meter and the rest of the fluid was sent to a commercial laboratory for analysis....

Background: Leptospirosis is a zoonotic bacterial infection that is common worldwide, with a wide spectrum of clinical signs. It commonly infects the kidneys and the liver but can damage a number of organ systems. Case description: An 18-month-old boxer dog was referred because of reluctance to...

Immune-mediated polyarthritis is frequently seen in dogs. It is a group of multiarticular inflammatory conditions of varied origin. There are basically two forms: erosive, which is very rare (1%), and non-erosive (based on radiographic criteria). Hypersensitivity reactions are frequently...

Nine dogs with history of lameness and anorexia were presented. On physical examination, all dogs had gait abnormality and six dogs had high body temperature. Their clinical signs were mostly episodic, and only non-specific symptoms were occasionally observed. Arthrocentesis was performed in all ...

Practical relevance: Osteoarthritis, a degenerative non-inflammatory joint disease, is common in cats, usually causing gradual changes in behavior and lifestyle rather than severe lameness. Inflammatory arthritis occurs much less frequently and is nearly always associated with debilitating...

A 9-year-old castrated male poodle dog was presented with icterus, anorexia, and lethargy. The dog was diagnosed with hypothyroidism 1 month before and was treated with levothyroxine. Severe anaemia with spherocytes, positive saline agglutination test, and hyperbilirubinemia indicated ...

Immune-mediated polyarthritis is frequently seen dogs. It is a group of multiarticular inflammatory conditions of varied origin. There are basically two forms: erosive, which is very rare (1%), and non-erosive (based on radiographic criteria). Hypersensitivity reactions are frequently implicated....

This paper aims at the presentation a novel approach in the immune-mediated and neoplastic diseases treatment in dogs and cats. Masitinib is selective tyrosine kinase inhibitor used for the treatment of mast cell tumors (MCTs) in dogs. This drug has also been efficacious in other neoplastic...

Background: Septic arthritis (SA) is a serious condition in dogs that requires a prompt diagnosis and treatment to minimize long-term joint pathology. Although bacterial detection in synovial fluid (SF) through culture or cytology is often performed to confirm diagnosis, the sensitivity of these...