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Abstract

The term tylosin-responsive diarrhoea (TRD) is used for canine recurrent diarrhoea cases for which no underlying cause can be found after extensive diagnostic investigations, but which show a response to the antibiotic tylosin in a few days. The objective of this prospective, one-arm longitudinal...

Author(s)
Kilpinen, S.; Rantala, M.; Spillmann, T.; Björkroth, J.; Westermarck, E.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2015, 205, 3, pp 369-374
AbstractFull Text

Background: Despite its wide acceptance as a treatment for canine chronic enteropathies, the macrolide antibiotic tylosin lacks official oral dosage recommendations. Not even textbooks share consensus about the dose; daily recommendations vary from 25 to 80 mg/kg and dosing intervals from one to...

Author(s)
Kilpinen, S.; Spillmann, T.; Westermarck, E.
Publisher
BioMed Central Ltd, London, UK
Citation
Acta Veterinaria Scandinavica, 2014, 56, 43, pp (6 August 2014)
Abstract

The aim of this study was to compare the clinical activity index (CCECAI), age at diagnosis, serum albumin concentrations and outcome at various time points after diagnosis between a group of dogs treated with dietary management alone (food-responsive diarrhoea [FRD]), diet and antimicrobials (...

Author(s)
Allenspach, K.; Culverwell, C.; Chan, D.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record, 2016, 178, 15, pp 368
AbstractFull Text

Background: The macrolid antibiotic tylosin has been widely used to treat canine chronic diarrhea, although its efficacy is based on anecdotal reports and experimental studies in dogs and not on strong scientific evidence. The term tylosin-responsive diarrhea (TRD) refers to diarrheal disorders...

Author(s)
Kilpinen, S.; Spillmann, T.; Syrjä, P.; Skrzypczak, T.; Louhelainen, M.; Westermarck, E.
Publisher
BioMed Central Ltd, London, UK
Citation
Acta Veterinaria Scandinavica, 2011, 53, 26, pp (14 April 2011)
Abstract

A two-year-old male dachshund was presented with a long-term history of chronic small intestine diarrhoea. The dog had been previously treated with several antibiotics, with temporary remission of clinical signs, relapsing each time the therapy was discontinued. On the basis of clinical signs,...

Author(s)
Menozzi, A.; Dall'Aglio, M.; Quintavalla, F.; Meucci, V.; Bertini, S.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2017, 5, 1, pp e000423
Abstract

Fourteen dogs had shown chronic or intermittent diarrhea for more than 1 year. Diarrhea had been successfully treated with tylosin for at least 6 months but recurred when treatment was withdrawn on at least 2 occasions. Tylosin-responsive diarrhea (TRD) affects typically middle-aged, large-breed ...

Author(s)
Westermarck, E.; Skrzypczak, T.; Harmoinen, J.; Steiner, J. M.; Ruaux, C. G.; Williams, D. A.; Eerola, E.; Sundbäck, P.; Rinkinen, M.
Publisher
American College of Veterinary Internal Medicine, Lakewood, USA
Citation
Journal of Veterinary Internal Medicine, 2005, 19, 2, pp 177-186
Abstract

Background: Canine chronic enteropathies (CE) are a group of intestinal diseases that can be categorized based on treatment response into diet- or food-responsive enteropathy (FRD), antibiotic-responsive enteropathy, steroid-responsive enteropathy, and non-responsive enteropathy. CE can often be...

Author(s)
Pilla, R.; Guard, B. C.; Steiner, J. M.; Gaschen, F. P.; Olson, E.; Werling, D.; Allenspach, K.; Salavati Schmitz, S.; Suchodolski, J. S.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 6, August, pp 277
Abstract

Background: Chronic diarrhea (CD) is common in dogs, and information on frequency and distribution of primary and secondary causes is lacking. Objectives: To evaluate underlying causes and predictors of outcome in dogs with CD. Animals: One hundred and thirty-six client-owned dogs with CD (≥3 weeks ...

Author(s)
Volkmann, M.; Steiner, J. M.; Fosgate, G. T.; Zentek, J.; Hartmann, S.; Kohn, B.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 4, pp 1043-1055
Abstract

S100A12 is a potential biomarker of gastrointestinal inflammation in dogs and fecal S100A12 concentrations are correlated with disease severity and outcome. The aim of the present study was to investigate whether there was any association between pre-treatment fecal S100A12 concentrations in dogs...

Author(s)
Heilmann, R. M.; Volkmann, M.; Otoni, C. C.; Grützner, N.; Kohn, B.; Jergens, A. E.; Steiner, J. M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2016, 215, pp 96-100
Abstract

Five dogs with chronic-recurring diarrhea were positive for Clostridioides difficile infection (CDI), but were unresponsive to treatment with metronidazole. One of these animals was subjected to a colonoscopy, which revealed eosinophilic infiltration of the colon. All five animals completely...

Author(s)
Silva, R. O. S.; Oliveira Júnior, C. A. de; Blanc, D. S.; Pereira, S. T.; Araujo, M. C. R. de; Vasconcelos, A.; Lobato, F. C. F.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Anaerobe, 2018, 51, pp 50-53

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