Alopecia X is a hair cycle arrest disorder in Pomeranians. Histologically, kenogen and telogen hair follicles predominate, whereas anagen follicles are sparse. The induction of anagen relies on the activation of hair follicle stem cells and their subsequent proliferation and differentiation. Stem...

Alopecia X is a type of dermatosis seen in young adult dogs and characterized by cessation of hair cycle, high progesterone, low androgen, variable estrogen and mild increase in cortisol, without inflammation and itching. Alaskan Malamute, Chow-Cow, Keeshond, Norwegian Elkhound, Pomeranian and...

Alopecia in dogs is a frequent finding at veterinary dermatological consultations, may be caused by various skin diseases and even systemic. Alopecia X is a dermatopathy that occurs most often in Nordic breeds, especially in German Spitz dogs, about which there is not much scientific knowledge...

Background: Schipperkes develop bilaterally symmetrical alopecia preceded by lightening of the hair coat not associated with systemic clinical signs. The alopecia is presumptively diagnosed as Alopecia X but has never been investigated. Hypothesis/Objectives: The purpose of this study was to...

A four-year-old Spitz dog, after returning from a bath and grooming, presented restlessness and pain when the owner touched him. It was then observed a wide and deep lesion by burn in the region of the back, being a patient with Alopecia X already treated. Only photobiomodulation therapy was used,...

Background: Alopecia X in dogs is a noninflammatory alopecia that may be caused by a hormonal dysfunction. It may be similar to androgenic alopecia in men that is caused by the effect of dihydrotestosterone (DHT). The 5α-reductase isoenzymes, 5αR1 and 5αR2, and a recently described 5αR3, are...

Background - Noninflammatory alopecia is a frequent problem in dogs, and the pathogenesis is still unclear. Objective - The objective of this study was a comparative histological description of skin biopsies from dogs with different alopecic disorders and control dogs matched for coat type, season...

Alopecia X or "hair follicle entrapment" is a common dermatopathy in veterinary dermatological consultations, characterized by a set of skin manifestations such as hair loss. Its etiology remains unknown to the present day, which justifies its name. The suspicion is that it is a hereditary disease, ...

Our objective was to characterize the use of 18F-fluorodeoxyglucose (FDG)-PET/CT in the diagnosis of primary splenic hemangiosarcoma in combination with histopathology and immunohistochemistry. A 7-year-old castrated male mixed breed dog weighing 6 kg was presented with the complain of recurring...

Background: Trichoblastoma is a rare skin neoplasm derived from the primitive hair follicle, having epithelial and mesenchymal components. Despite being commonly described as a benign tumor, there are reports in the literature of tumors with characteristics of malignant neoplasia. It affects adult ...