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AbstractFull Text

Canine visceral leishmaniasis is an endemic zoonosis in Brazil. Dogs are the main hosts in urban environments. The treatment has gained popularity since the Brazilian government authorized miltefosine for canine treatment. The aim of this study was to investigate the clinical and parasitological...

Author(s)
Ayres, E. da C. B. S.; Dias, Á. F. de L. R.; Monteiro, B. R. G.; Pazzini, S. S.; Barbosa, M. E. C.; Silva, E. B. da; Macedo, L. F. da C.; Sousa, V. R. F.; Dutra, V.; Nakazato, L.; Almeida, A. do B. P. F. de
Publisher
Colégio Brasileiro de Parasitologia Veterinária, São Paulo, Brazil
Citation
Brazilian Journal of Veterinary Parasitology, 2022, 31, 3,
Abstract

The objective of this study was to describe the adverse effects of allopurinol on the urinary system during treatment of canine leishmaniasis. Retrospective case series of 42 dogs that developed xanthinuria while receiving allopurinol treatment for leishmaniasis. 42 (13%) of the 320 dogs with...

Author(s)
Rivière, D.; Lavabre, T.
Publisher
Newsmed, Paris, France
Citation
Point Vétérinaire, 2021, 52, 419 Part 1, pp 5-6
Abstract

Xanthinuria is a significant adverse effect in dogs on long-term allopurinol for treatment of leishmaniosis. The study aims to investigate how the Iberian veterinary community (IVC) identifies, manages, and proactively prevents xanthinuria secondary to allopurinol treatment. A cross-sectional study ...

Author(s)
Jesus, L.; Arenas, C.; Domínguez-Ruiz, M.; Silvestrini, P.; Englar, R. E.; Roura, X.; Leal, R. O.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Comparative Immunology, Microbiology & Infectious Diseases, 2022, 83,
Abstract

First-line treatment for canine leishmaniosis (CanL) is N-methylglucamine antimoniate (MGA) combined with allopurinol. However, in some dogs allopurinol may induce hyperxanthinuria leading to urolithiasis. Moreover, allopurinol resistance has recently been described in Leishmania infantum isolates...

Author(s)
Segarra, S.; Miró, G.; Montoya, A.; Pardo-Marín, L.; Boqué, N.; Ferrer, L.; Cerón, J.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2017, 239, pp 50-56
Abstract

Allopurinol is the most commonly used drug for the treatment of hyperuricemia in people, and in view of the risks of fatal hypersensitivity in patients with renal dysfunction, doses based on the glomerular filtration rate are proposed. In veterinary medicine, allopurinol is used in the treatment of ...

Author(s)
Godoy, A. L. P. C.; Jesus, C. de; Gonçalves, R. S.; Azeredo, F. J.; Rocha, A.; Marques, M. P.; Lanchote, V. L.; Larangeira, D. F.; Barrouin-Melo, S. M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Journal of Pharmaceutical and Biomedical Analysis, 2020, 185,
AbstractFull Text

This paper describes a case of canine visceral Leishmaniasis resistant to Meglumine Antimoniate plus allopurinol treatment in a canine patient from Colombia. A one-year-old castrated dog of the schnauzer breed was referred for veterinary consultation for showing a 2-month history of dermatological...

Author(s)
Pinilla, J. C.; Gutierrez, A.; Florez, A. A.
Publisher
Faculty of Agriculture, Nnamdi Azikiwe University, Anambra, Nigeria
Citation
International Journal of Veterinary Science, 2022, 11, 1, pp 117-120
AbstractFull Text

In Argentina, human leishmaniosis treatment is regulated by means of the therapeutic scheme suggested by WHO and is provided by the government. The objective of this present work was to evaluate the progression of clinical signs, laboratory values and parasitic load at the beginning and during the...

Author(s)
Llano, E. G.; Maidana, H. R.; Báez, A. D.; Cabrera, W. R.; Benítez, J. S.
Publisher
Facultad de Ciencias Veterinarias de la Universidad Nacional del Nordeste (UNNE), Corrientes, Argentina
Citation
Revista Veterinaria, 2020, 31, 1, pp 20-27
Abstract

The aim of this 6-month, randomized, blinded, controlled clinical trial was to compare the efficacy and safety of aminosidine-allopurinol combination with that of meglumine antimoniate-allopurinol combination for the treatment of leishmaniosis in dogs without stage III or IV chronic kidney disease. ...

Author(s)
Kasabalis, D.; Chatzis, M. K.; Apostolidis, K.; Petanides, T.; Athanasiou, L. V.; Xenoulis, P. G.; Mataragka, A.; Ikonomopoulos, J.; Leontides, L. S.; Saridomichelakis, M. N.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Experimental Parasitology, 2020, 214,
Abstract

Background: Canine leishmaniosis (CanL) can be appropriately managed following international recommendations. However, few studies have assessed the preferred protocols in real-life veterinary practice and whether these are in line with the guidelines. This survey aimed to investigate the current...

Author(s)
Monteiro, M.; Prata, S.; Cardoso, L.; Fonseca, I. P. da; Leal, R. O.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2021, 14, 306, pp (7 June 2021)
Abstract

Visceral leishmaniasis (VL) is an infectious disease caused by the protozoan parasite Leishmania (Leishmania) infantum, an intracytoplasmic parasite that affects humans and other species of domestic and wild mammals. In Brazil, the treatment of canine visceral leishmaniasis (CVL) with miltefosine...

Author(s)
Dias, Á. F. de L. R.; Ayres, E. da C. B. S.; Martins, D. T. de O.; Maruyama, F. H.; Oliveira, R. G. de; Carvalho, M. R. de; Almeida, A. do B. P. F. de; Teixeira, A. L. de S.; Mendonça, A. J.; Sousa, V. R. F.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Experimental Parasitology, 2020, 217,

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