Objectives: To evaluate sedation quality and cardiorespiratory variables in dogs sedated using a target-controlled infusion of propofol or propofol-alfentanil admixture. Methods: A total of 60 dogs undergoing diagnostic imaging were randomly assigned to one of three sedation protocols: propofol...

Objective: To determine whether the administration of trazodone to dogs 2 hours prior to radiotherapy treatment reduced the dose of propofol required to induce anaesthesia. Study design: Retrospective, crossover, case-matched study. Animals: Records of 30 client-owned dogs. Methods: Anaesthetic...

Objectives: To describe alfentanil-propofol admixture for induction of anaesthesia for canine radiotherapy and compare it to alfentanil-atropine followed by propofol induction in terms of heart rate (HR), mean arterial pressure (MAP), recovery duration and quality. Study design: Prospective,...

The aim of this study was to compare the cardiovascular and respiratory effects and the bispectral scale index (BIS) as well as the recovery period characteristics in response to treatment with a propofol/alfentanil admixture of different concentrations in dogs undergoing splenectomy. We conducted...

A 7-month-old, 12.2 kg, male, neutered, English bulldog with severe pulmonary stenosis and R2A right coronary artery anomaly was anaesthetised for placement of hybrid right ventricle to pulmonary artery stent. An alfentanil bolus (10 μg/kg intravenously) was used as premedication. Anaesthesia was...

Objective - To compare induction targets, and the haemodynamic and respiratory effects, of propofol, or as an admixture with two different concentrations of alfentanil, delivered via a propofol target-controlled infusion (TCI) system. Study design - Prospective blinded randomized clinical study....

In older patients, it is important to minimise anaesthesia-related deaths and complications. In this study, 2 separate anaesthesia inductions were evaluated with respect to their effects on heart rate, respiratory rate, pulse oximetry data, intraocular pressure, and body temperature. A total of 22 ...

This case report describes the diagnosis, the treatment options available in the absence of dantrolene and outcome of anaesthesia-related hyperthermia seen for the first time in an Anatolian shepherd dog. The case consisted of a nine-month-old male Anatolian shepherd dog with bilateral antebrachium ...

In animal health risk assessment, hazard characterisation of feed additives has been often using the default uncertainty factor (UF) of 100 to translate a no-observed-adverse-effect level in test species (rat, mouse, dog, rabbit) to a 'safe' level of chronic exposure in farm and companion animal...

Three groups of 10 dogs undergoing orthopaedic surgery were anaesthetized with halothane. After stabilization of anaesthesia, the dogs received i.v. fentanyl (5 µg/kg), sufentanil (1 µg/kg) or alfentanil (25 µg/kg). Cardiovascular and respiratory parameters were measured at various times throughout ...