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Abstract

Objective: To determine the effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone required to prevent movement in response to a noxious stimulus (MIRNM) in dogs. Study design: Experimental crossover design. Animals: A group of six healthy, adult, intact female mixed-breed ...

Author(s)
Bennett, K. J.; Seddighi, R.; Moorhead, K. A.; Messenger, K.; Cox, S. K.; Sun XiaoCun; Pasloske, K.; Pypendop, B. H.; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 2, pp 173-181
Abstract

The purpose of this study was to evaluate the effects of a single intravenous dose of alfaxalone on canine splenic volume. In 6 adult beagle dogs the splenic volume [mean±standard error (SE)] was determined by computed tomography to be 0.17±0.02 L before alfaxalone administration and 0.24±0.02 L (...

Author(s)
Hasiuk, M. M. M.; Garcia-Pereira, F. L.; Berry, C. R.; Ellison, G. W.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2018, 82, 3, pp 203-207
Abstract

Background: The purpose of this study was to determine the effects of isoflurane, sevoflurane, propofol and alfaxalone on the canine brain metabolite bioprofile, measured with single voxel short echo time proton magnetic resonance spectroscopy at 3 Tesla. Ten adult healthy Beagle dogs were assigned ...

Author(s)
Söbbeler, F. J.; Carrera, I.; Pasloske, K.; Ranasinghe, M. G.; Kircher, P.; Kästner, S. B. R.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 69, pp (5 March 2018)
Abstract

Objective: To study the effect of alternating the order of midazolam and alfaxalone administration on the incidence of behavioural changes, alfaxalone induction dose and some cardiorespiratory variables in healthy dogs. Study design: Prospective, randomized, controlled, clinical trial. Animals: A...

Author(s)
Zapata, A.; Laredo, F. G.; Escobar, M.; Agut, A.; Soler, M.; Belda, E.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2018, 45, 5, pp 609-617
AbstractFull Text

The aim of this study was to compare alfaxalone and propofol in balanced anaesthesia using midazolam 0.5 mg/kg, xylazine 0.125 mg/kg, butorphanol 0.2 mg/kg intravenously as premedication and the ultrashort acting anaesthetics alfaxalone or propofol for inducing and maintaining in dogs with...

Author(s)
Capik, I.; Polkovska, I.; Lukac, B.
Publisher
Czech Academy of Agricultural Sciences, Prague, Czech Republic
Citation
Veterinární Medicína, 2019, 64, 8, pp 335-341
Abstract

Objective: To compare cardiovascular effects and anaesthetic quality of alfaxalone alone or in combination with a fentanyl constant rate infusion (CRI) when used for total intravenous anaesthesia (TIVA) in dogs. Study design: Prospective, blinded, randomized, experimental study. Animals: A group of ...

Author(s)
Dehuisser, V.; Bosmans, T.; Kitshoff, A.; Duchateau, L.; Rooster, H. de; Polis, I.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2017, 44, 6, pp 1276-1286
Abstract

This blinded, randomized, prospective study evaluated the sedative and physiologic effects of a combination of alfaxalone and methadone with or without midazolam in adult dogs. Sixteen dogs received methadone (0.5 mg/kg body weight) and alfaxalone (1 mg/kg body weight), either with or without...

Author(s)
Micieli, F.; Chiavaccini, L.; Paré, M. D.; Chagas, J. B.; Vesce Giancarlo; Gianotti, G.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2019, 60, 10, pp 1060-1064
Abstract

Objective: To describe clinically relevant, physiological measurements collected during a 3 hour duration of alfaxalone total intravenous anaesthesia. Study design: Case series. Animals: A total of 112 client-owned middle-aged or older dogs. Methods: Dogs were premedicated with intramuscular...

Author(s)
Hunt, J. R.; Goff, M.; Jenkins, H.; Harris, J.; Knowles, T. G.; Lascelles, B. D. X.; Mendl, M.; Whay, H. R.; Murrell, J. C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 4, pp 483-487
Abstract

OBJECTIVE: To compare effects of tiletamine-zolazepam, alfaxalone, ketamine-diazepam, and propofol for anesthetic induction on cardiorespiratory and acid-base variables before and during isoflurane-maintained anesthesia in healthy dogs. ANIMALS: 6 dogs. PROCEDURES: Dogs were anesthetized with...

Author(s)
Hampton, C. E.; Riebold, T. W.; LeBlanc, N. L.; Scollan, K. F.; Mandsager, R. E.; Sisson, D. D.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2019, 80, 1, pp 33-44
Abstract

Objective To determine the effects of two dexmedetomidine continuous rate infusions on the minimum infusion rate of alfaxalone for total intravenous anaesthesia (TIVA), and subsequent haemodynamic and recovery effects in Greyhounds undergoing laparoscopic ovariohysterectomy. Study design...

Author(s)
Quirós-Carmona, S.; Navarrete, R.; Domínguez, J. M.; Granados, M. del M.; Gómez-Villamandos, R. J.; Muñoz-Rascón, P.; Aguilar, D.; Funes, F. J.; Morgaz, J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2017, 44, 2, pp 228-236

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