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Abstract

We aimed to evaluate the induction, anesthesia, and cardiorespiratory effects of intramuscular (IM) anesthetic protocol with alfaxalone following premedication with low-dose medetomidine, butorphanol, or a combination of both (medetomidine-butorphanol) in dogs. Six healthy beagles were administered ...

Author(s)
Kato, K.; Itami, T.; Nomoto, K.; Endo, Y.; Tamura, J.; Oyama, N.; Sano, T.; Yamashita, K.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2021, 83, 1, pp 53-61
Abstract

Laryngeal paralysis is a well-documented cause of upper respiratory tract obstruction in canines. Diagnosis of laryngeal paralysis is usually made by visual evaluation of laryngeal motion whilst patients are under a light-plane of anesthesia. However, in human studies of laryngeal function...

Author(s)
Pan PoChing; Savidge, C.; Amsellem, P.; Hamilton, S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2022, 17, 7,
Abstract

Objective: To determine the alfaxalone dose reduction during total intravenous anaesthesia (TIVA) when combined with ketamine or midazolam constant rate infusions and to assess recovery quality in healthy dogs. Study design: Prospective, blinded clinical study. Animals: A group of 33 healthy,...

Author(s)
Bustamante, R.; Gómez Segura, I. A. de; Canfrán, S.; Aguado, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 4, pp 437-446
Abstract

PICO questionIn routine canine caesareans, is alfaxalone a superior anaesthetic induction agent than propofol in increasing the rate of survival and vigour of neonates? Clinical bottom line Category of research question Treatment The number and type of study designs reviewed Three randomised...

Author(s)
Sofyan, L. M.; Taboada, F. M.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2021, 6, 2,
Abstract

Objective: To determine the effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone required to prevent movement in response to a noxious stimulus (MIRNM) in dogs. Study design: Experimental crossover design. Animals: A group of six healthy, adult, intact female mixed-breed ...

Author(s)
Bennett, K. J.; Seddighi, R.; Moorhead, K. A.; Messenger, K.; Cox, S. K.; Sun XiaoCun; Pasloske, K.; Pypendop, B. H.; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 2, pp 173-181
Abstract

OBJECTIVE: To evaluate and compare the anesthetic effects of alfaxalone-ketamine-midazolam (AKM) and alfaxalone-ketamine-dexmedetomidine (AKD) in black-tailed prairie dogs (Cynomys ludovicianus). ANIMALS: 9 male black-tailed prairie dogs. PROCEDURES: Prairie dogs were anesthetized with AKM (6 mg/kg ...

Author(s)
Hiebert, K.; Eshar, D.; Sarvi, J.; Beaufrère, H.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2022, 83, 9,
Abstract

The purpose of this study was to evaluate the effects of a single intravenous dose of alfaxalone on canine splenic volume. In 6 adult beagle dogs the splenic volume [mean±standard error (SE)] was determined by computed tomography to be 0.17±0.02 L before alfaxalone administration and 0.24±0.02 L (...

Author(s)
Hasiuk, M. M. M.; Garcia-Pereira, F. L.; Berry, C. R.; Ellison, G. W.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2018, 82, 3, pp 203-207
Abstract

Objective To compare the effects of sevoflurane, propofol and alfaxalone on the neuromuscular blockade induced by a single intravenous bolus of rocuronium in dogs. Study design: A randomized, prospective, crossover experimental study. Animals: A total of eight adult Beagle dogs (four female, four...

Author(s)
Chen, I. Y.; Tamogi, H.; Wei, Y.; Kato, K.; Itami, T.; Sano, T.; Yamashita, K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2022, 49, 1, pp 36-44
Abstract

Background: The purpose of this study was to determine the effects of isoflurane, sevoflurane, propofol and alfaxalone on the canine brain metabolite bioprofile, measured with single voxel short echo time proton magnetic resonance spectroscopy at 3 Tesla. Ten adult healthy Beagle dogs were assigned ...

Author(s)
Söbbeler, F. J.; Carrera, I.; Pasloske, K.; Ranasinghe, M. G.; Kircher, P.; Kästner, S. B. R.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 69, pp (5 March 2018)
Abstract

Anesthetics may worsen the outcome of patients undergoing oncologic surgery via immune suppression. This study examines the impact of propofol, ketamine, and alfaxalone on canine peripheral blood lymphocyte (PBL) cytotoxic function in vitro. PBLs isolated from healthy canine blood were cultured in...

Author(s)
Barr, C. A.; Alvarado, F.; Chang YuMei; Luo Jie; Garden, O. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2021, 136, pp 182-184

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