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Abstract

Clonality testing for rearrangements in the complementarity-determining region 3 of the immunoglobulin heavy chain of B lymphocytes (B cell receptor) and the T cell receptor of T lymphocytes helps distinguish between clonal and non-clonal expansions of lymphocytes. There are rare reports of...

Author(s)
Stokol, T.; Nickerson, G. A.; Shuman, M.; Belcher, N.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2017, 4, May, pp 76
Abstract

BACKGROUND: Flow cytometry may be used to determine immunophenotype or lineage of leukemic cells, but few antibodies are available that are specific for cells of monocytic and granulocytic lineage. OBJECTIVE: The purpose of this study was to evaluate the flow cytometric staining patterns of 3...

Author(s)
Villiers, E.; Baines, S.; Law, A. M.; Mallows, V.
Publisher
American Society for Veterinary Clinical Pathology, Madison, USA
Citation
Veterinary Clinical Pathology, 2006, 35, 1, pp 55-71
Abstract

Acute myeloid leukemia (AML) is a type of neoplasm that is characterized by infiltration, especially in the bone marrow and peripheral blood, by undifferentiated cells of the hematopoietic system. In general, chemotherapy in dogs with AML is ineffective and patients have an unfavorable prognosis....

Author(s)
Medeiros, V. B.; Macêdo, L. B. de; Pimentel, M. M. L.; Oliveira, I. V. P. de M.; Vale, A. M. do; Filgueira, K. D.
Publisher
Fedearl University of Ceará, Fortaleza, Brazil
Citation
Revista Brasileira de Higiene e Sanidade Animal, 2016, 10, 4, pp 708-715
Abstract

Acute myeloid leukaemia (AML) is an uncommon, rapidly progressive neoplasm in dogs. The aim of this retrospective study was to characterize the clinical presentation, haematologic findings, diagnostic imaging results, treatment and survival time of a contemporary cohort of dogs with AML. Diagnosis...

Author(s)
Davis, L. L.; Hume, K. R.; Stokol, T.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2018, 16, 2, pp 268-275
Abstract

Background: Immunophenotyping has replaced cytochemical staining as the preferred technique for classifying acute leukemia. However, some acute myeloid leukemias (AML) lack lineage-associated markers. In our experience, alkaline phosphatase (ALP) is expressed in immature canine monocytes. We...

Author(s)
Stokol, T.; Schaefer, D. M.; Shuman, M.; Belcher, N.; Dong, L.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Veterinary Clinical Pathology, 2015, 44, 1, pp 79-93
Abstract

Acute myeloid leukemia is an uncommon hematopoietic neoplasm of dogs that should be differentiated from lymphoid neoplasms, such as lymphoma, because of different treatment protocols and a worse prognosis. Thoracic radiography is performed frequently in dogs with suspected hematopoietic neoplasia,...

Author(s)
Epperly, E.; Hume, K. R.; Moirano, S.; Stokol, T.; Intile, J.; Erb, H. N.; Scrivani, P. V.
Publisher
Wiley, Boston, USA
Citation
Veterinary Radiology & Ultrasound, 2018, 59, 5, pp 507-515
Abstract

Tumours shows aberrant DNA methylation patterns, being hypermethylated or hypomethylated compared with normal tissues. In human acute myeloid leukaemia (hAML) mutations in DNA methyltransferase (DNMT3A) are associated to a more aggressive tumour behaviour. As AML is lethal in dogs, we defined...

Author(s)
Bronzini, I.; Aresu, L.; Paganin, M.; Marchioretto, L.; Comazzi, S.; Cian, F.; Riondato, F.; Marconato, L.; Martini, V.; Kronnie, G. te
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2017, 15, 3, pp 910-918
Abstract

Traditionally, classification of leukaemia in dogs has relied on morphological examination and cytochemical staining patterns, but aberrant cellular morphology and stain uptake often curtails accurate categorization, and historical data based on this classification may be unreliable....

Author(s)
Adam, F.; Villiers, E.; Watson, S.; Coyne, K.; Blackwood, L.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2009, 7, 3, pp 181-195
Abstract

Publisher
Elsevier Inc., Philadelphia, USA
Citation
Advances in Small Animal Medicine and Surgery, 2020, 33, 2, pp 6-6
AbstractFull Text

The aim of this study is to report a case of acute myeloid leukemia (AML) in a dog infected by Leishmaniaspp. and other infectious agents. An 8-year-old, male Poodle, was brought to the Veterinary Hospital from Universidade Federal Rural do Semi-Árido. The dog had a history of recurrent tick-borne...

Author(s)
Bezerra, J. A. B.; Rodrigues, R. T. G. A.; Lima, I. de O.; Vale, A. M. do; Filgueira, K. D.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2018, 46, Supplement, pp 260

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