Previously, antioxidants have not been evaluated for treatment of parvoviral diarrhea in dogs. In this study, antioxidant potential of N-acetylcysteine (NAC) in dogs infected with canine parvovirus with a nonblinded randomized clinical trial has been carried out. A total 18 parvo-infected dogs were ...

Pseudomonas aeruginosa is one of the most common pathogenic species associated with canine otitis externa (OE). Their resilience is achieved by forming a biofilm, which allows these bacteria to evade even the harshest of treatments. This study evaluated the in vitro synergistic efficacy of N-...

13 year-old male dog with complaints of fever, loss of appetite, stagnation as well as respiratory signs such as purulent nasal and eye discharge, cough and neurologic signs including apathy, ataxia, quadriplegia, muscular atrophy and myoclonus which admitted to the Animal Hospital of Faculty of...

The project of research was carrying out to study the effect of N-acetylcysteine on the wounds which developed in the stomach after gastrotomy. Dogs were used in this study as experimental animals. Dogs were divided into two groups' treatment and control; each group contains 5 animals. The surgical ...

OBJECTIVE: To describe intracanalicular injection of 10% N-acetylcysteine (IINAC) as adjunctive treatment for sialoceles in dogs. ANIMALS: 25 client-owned dogs. PROCEDURES: Hard copy medical records at 2 veterinary ophthalmology practices were searched to identify dogs that underwent IINAC for...

To determine the in vitro antimicrobial activity of N-acetylcysteine (NAC) against common pathogens associated with infectious keratitis in dogs and cats, clinical isolates of Staphylococcus (S.) pseudintermedius (n = 20), Streptococcus (St.) canis (n = 10) and Pseudomonas (P.) aeruginosa (n = 7)...

OBJECTIVE: To evaluate the in vitro effect of 20% N-acetylcysteine (NAC) on the viscosity of normal canine bile. ANIMALS: Bile samples obtained from 10 adult dogs euthanized for reasons unrelated to biliary disease. PROCEDURES: Each sample was centrifuged to remove particulates, then divided into 3 ...

This study aimed to investigate the effect of N-acetyl-L-cysteine (NAC) on oxidative damage of lens epithelium in the beagle model of type 1 diabetes mellitus. Forty beagles, 2-3 years old, were randomly divided into control group (CON group), diabetes model group (DM group), insulin treatment...

A 4-year-old female spayed Pomeranian was referred to the emergency service for intermittent trouble breathing and an enlarged liver found on ultrasound. A severe mixed hepatopathy was found on bloodwork, and ultrasound-guided liver aspirates showed marked hepatocellular vacuolar changes and rare...

Background: Approved treatments for canine otitis externa are limited in variety and may contain ototoxic ingredients. With bacterial resistance an ongoing concern, it would be ideal if non-ototoxic agents combined with antibiotics resulted in a synergistic effect, requiring lower antibiotic...