Acanthosis nigricans with mixed infection of Staphylococcus and Malassazia spp. in one year old female Labrador was diagnosed and managed.

Efficacy of melatonin in the treatment of acanthosis nigricans was evaluated in 32 Dachshunds (14 females and 18 males) aged 7 months to 7 years. Animals were allocated into 2 groups based on the severity of skin lesions: group I of 21 dogs aged up to 2 years and group II of 11 dogs older than 2...

A 10-year-old male German Shepherd dog in Romania was presented for anorexia and a 2-month history of progressive alopecia, gynecomastia and hyperpigmented skin [date not given]. Physical examination showed a large scrotal tumour, secondary paraneoplastic feminization syndrome (nipple enlargement,...

When eight Dachshunds with primary acanthosis nigricans were given 200 IU dl-alpha-tocopherol acetate orally twice a day (two hours before or after a meal), improvement occurred in 60 days. Inflammation, lichenification, pruritus, greasiness and objectionable odour subsided, although the visible...

Long-term corticosteroid (betamethasone) therapy produced a clinical improvement in the skin condition of three dogs with acanthosis nigricans. The administration of TSH, and the stimulation of endogeneous TSH production, failed to produce a satisfactory response.

The condition is reviewed, and compared with acanthosis nigricans in man. Acanthosis in dogs is particularly common in the dachshund, but occurs in Airedales, German Shepherd and dwarf breeds. About ten cases were detected among thousands of dogs examined at the Alfort Veterinary College over a...

Pituitary tumours associated with Cushing's syndrome and diabetes insipidus are described in 10 dogs. All dogs showed typical clinical signs including polyuria/polydipsia and acanthosis nigricans. Neuropathological findings and immunohistochemistry of hormone (ACTH, MSH) secretions are presented;...