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Abstract

An 8-month-old female Great Pyrenees dog with chronic epistaxis and a history of gingival bleeding during shedding of deciduous teeth was evaluated for platelet function. Platelet morphology was normal at both the light and electron microscopic level. Platelet number and mean platelet volume were...

Author(s)
Boudreaux, M. K.; Kvam, K.; Dillon, A. R.; Bourne, C.; Scott, M.; Schwartz, K. A.; Toivio-Kinnucan, M.
Citation
Veterinary Pathology, 1996, 33, 5, pp 503-511
Abstract

The study was conducted on 57 dogs (13 affected, 23 carrier, 17 unaffected and 4 clinically healthy Otterhounds) to determine the molecular and genetic basis for thrombasthenic thrombopathia in Otterhounds and establish whether the defect would be best classified as type-I Glanzmann's ...

Author(s)
Boudreaux, M. K.; Catalfamo, J. L.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2001, 62, 11, pp 1797-1804
Abstract

Glannzmann's thrombasthenia (GT) is an autosomal recessive bleeding disorder caused by qualitative or quantitative deficiencies of the platelet membrane glycoprotein αIIbβ3. This is the first report of a molecular genetic basis for type I GT in dogs. As previously reported, a thrombasthenic Great...

Author(s)
Lipscomb, D. L.; Bourne, C.; Boudreaux, M. K.
Publisher
American College of Veterinary Pathologists Inc, Lawrence, USA
Citation
Veterinary Pathology, 2000, 37, 6, pp 581-588
Abstract

Author(s)
Boudreaux, M. K.; Lipscomb, D. L.
Publisher
American College of Veterinary Pathologists Inc, Lawrence, USA
Citation
Veterinary Pathology, 2001, 38, 3, pp 249-260
Abstract

Thromboelastography (TEG) is a viscoelastic, whole blood-based assay that integrates information from both the cellular and soluble components of coagulation, providing a global evaluation of the haemostatic system. This contrasts with the conventional coagulation assays (i.e. platelet count,...

Author(s)
Mendez-Angulo, J. L.; Mudge, M. C.; Couto, C. G.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Education, 2012, 24, 12, pp 639-649
Abstract

An inherited intrinsic platelet aggregation defect has been identified in Basset Hounds that clinically resembles the human disease, Glanzmann's thrombasthenia. The defect was named Basset Hound Hereditary Thrombopathy (BHT), and initial studies revealed variably prolonged bleeding times, normal...

Author(s)
Patterson, W. R.
Citation
Dissertation Abstracts International, B, 1987, 47, 9, pp 3714

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