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Abstract

Hypophysectomy specimens from 16 dogs with pituitary adenoma were evaluated with periodic acid-Schiff (PAS), reticulin, and immunohistochemistry for adrenocorticotrophic hormone (ACTH), melanocyte stimulating hormone (MSH), growth hormone (GH), and Ki-67. The reticulin network was obliterated in...

Author(s)
Miller, M. A.; Owen, T. J.; Bruyette, D. S.; Scott-Moncrieff, J. C.; Ramos-Vara, J. A.; Weng HsinYi; Chen, A. V.; Martin, L. G.; DuSold, D. M.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Veterinary Pathology, 2018, 55, 6, pp 889-895
Abstract

Purpose: To evaluate the protein expression of somatostatin receptor (SSTR) 2, SSTR5 and dopamine D2 receptor (DA2R) - targets of somatostatin analogs and dopamine agonists - in normal canine pituitary and canine adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas. Methods: Six normal ...

Author(s)
Sato, A.; Hara, Y.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2018, 119, pp 61-66
Abstract

Background: In dogs with pituitary-dependent hypercortisolaemia, retinoic acid was shown to lower cortisol, reduce pituitary tumour size and decrease clinical signs when administered for six months. Oral vitamin A (retinol) has been used to treat various canine dermatoses in which retinoic acid has ...

Author(s)
Frank, L. A.; Morandi, F.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2021, 32, 4, pp 371-e104
Abstract

Primary hypoadrenocorticism is characterized by insufficient adrenocortical hormonal secretion of glucocorticoids and mineralocorticoids, which causes unspecific signs and laboratory alterations such as hyponatremia and hyperkalemia, resulting in a low relation between these two electrolytes. The...

Author(s)
Camilo, C. P.; Cardoso, M. J. L.; Marchi, P. N. de; Fagnani, R.
Publisher
TÜBITAK, Ankara, Turkey
Citation
Turkish Journal of Veterinary & Animal Sciences, 2021, 45, 1, pp 78-85
Abstract

Background: Standard protocols for adrenocorticotropic hormone (ACTH) stimulation testing (ACTHst) often involve intravenous (IV) injection of corticotropin. ACTH might be unintentionally injected into the perivascular (PV) space. Objective: To compare stimulation test results after IV and PV...

Author(s)
Johnson, C. M.; Kass, P. H.; Cohen, T. A.; Feldman, E. C.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 3, pp 730-733
Abstract

Pituitary-dependent hyperadrenocorticism (PDH) is mainly caused by pituitary corticotroph tumors in dogs. A characteristic feature of corticotroph tumors is their resistance to negative feedback by glucocorticoids. In some animal species, including dogs, the aberrant expression of...

Author(s)
Teshima, T.; Matsumoto, H.; Okusa, T.; Uchiyama, R.; Koyama, H.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2016, 11, 11, pp e0166267
Abstract

A 2-year-old female neutered English bull terrier presented with a history of behavioural change (depression, lethargy, avoidance of light), a mild increase in thirst and urination and two episodes of collapse. General physical and neurological examinations were unremarkable. Initial investigations ...

Author(s)
Raj, J.; Lara, A. S.; Bell, R.; Tappin, S.
Publisher
Wiley, Chichester, UK
Citation
Veterinary Record Case Reports, 2021, 9, 2,
Abstract

Background: Low-dose ACTH stimulation testing would lower cost and may increase sensitivity for identification of partial ACTH deficiency. Hypothesis: (1) The low-dose ACTH stimulation test will provide comparable results to the standard-dose ACTH stimulation test in dogs suspected of...

Author(s)
Botsford, A.; Behrend, E. N.; Kemppainen, R. J.; Gaillard, P. R.; Oprandy, F.; Lee, H. P.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2018, 32, 6, pp 1886-1890
Abstract

PICO question: In dogs with hyperadrenocorticism that are being treated with trilostane, does the measurement of basal cortisol levels have comparable diagnostic performance to the adrenocorticotropic hormone (ACTH) stimulation test? Clinical bottom line: Category of research question: Diagnosis...

Author(s)
Tsouloufi, T.; Oikonomidis, I.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2021, 6, 3,
AbstractFull Text

Background: The expression and overexpression of luteinizing hormone (LH) receptors in the canine adrenal gland cortex have been reported. Therefore, it was hypothesized that a LH-dependent form of Cushing's syndrome (CS) could exist in dogs. Aim: To assess whether the adrenal gland...

Author(s)
Espiñeira, I. M.; Vidal, P. N.; Ghersevich, M. C.; Arias, E. A. S.; Bosetti, F.; Blatter, M. F. C.; Miceli, D. D.; Castillo, V. A.
Publisher
Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
Citation
Open Veterinary Journal, 2021, 11, 2, pp 319-329

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