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Abstract

Dogs with pulmonary hypertension following administration of thiacetarsamide adulticide for Dirofilaria immitis infection were given antihistamine treatment under anaesthesia. Neither diphenhydramine (an H1 blocker) nor cimetidine (an H2 blocker) reduced pulmonary arterial pressure (PPA) at...

Author(s)
Rawlings, C. A.; Tackett, R. L.
Citation
American Journal of Veterinary Research, 1990, 51, 10, pp 1565-1569
Abstract

Seventeen dogs with naturally acquired infections of D. immitis were studied before and after thiacetarsamide treatment, using physical examinations, arterial blood gas analyses, thoracic radiography, and pulmonary haemodynamic and arteriographic tests. Eight dogs were considered to have a low...

Author(s)
Rawlings, C. A.; Tonelli, Q.; Lewis, R. E.; Duncan, J. R.
Citation
American Journal of Veterinary Research, 1993, 54, 6, pp 914-919
Abstract

Because melarsomine dihydrochloride (RM340) has been shown to be more effective in killing D. immitis than the traditional approved adulticide, thiacetarsamide, an attempt was made to determine whether this new adulticide induced more severe lung disease. Before adulticide treatment, 32 dogs with...

Author(s)
Rawlings, C. A.; Raynaud, J. P.; Lewis, R. E.; Duncan, J. R.
Citation
American Journal of Veterinary Research, 1993, 54, 6, pp 920-925
Abstract

Twelve dogs were infused with 1010Escherichia coli/kg of body weight through a portal vein catheter over a 1-hour period; 6 dogs were treated with flunixin meglumine (1 mg/kg) 15 minutes after the infusion had begun. Six dogs (controls) were infused with a comparable volume of sterile saline...

Author(s)
Hardie, E. M.; Rawlings, C. A.; Shotts, E. B., Jr.; Waltman, D. W.; Rakich, P. M.
Citation
American Journal of Veterinary Research, 1987, 48, 1, pp 56-62
Abstract

Pulmonary hypertension associated with myointimal proliferation develops in chronic Dirofilaria immitis infection. This study correlated changes in pulmonary artery haemodynamics and arteriograms with vascular alterations examined with scanning and light microscopy (SEM, LM) during infection and...

Author(s)
Rawlings, C. A.; Keith, J. C.; Schaub, R. G.
Citation
Federation Proceedings, 1981, 40, 3, I, pp 794
Abstract

Clinical, haematological, arteriographical, radiographical, and morphological responses to dying heartworms were characterized in seven infected Beagles after arsenamide therapy. The Beagles, infected 27 or 31 months previously with 99 or 100 infective D. immitis (DI) larvae, had DI-induced...

Author(s)
Rawlings, C. A.; Losonsky, J. M.; Schaub, R. G.; Greene, C. E.; Keith, J. C.; McCall, J. W.
Citation
American Journal of Veterinary Research, 1983, 44, 1, pp 8-15
Abstract

Cardiopulmonary function in Beagles that had been infected 18 months previously with 100 infective Dirofilaria immitis larvae was studied before and after an exercise programme. The treadmill exercise programme lasted for 2.5 months at 5 days/week until the dogs were running for 20 min at 11.3 km/h ...

Author(s)
Rawlings, C. A.
Citation
American Journal of Veterinary Research, 1981, 42, 12, pp 2057-2060
Abstract

Clinical manifestations of Dirofilaria immitis infection are reviewed under the headings pathophysiology and thoracic radiographic signs pulmonary thromboembolic disease and arterial obstruction, preadulticide thromboembolic complications, pneumonitis associated with occult heartworm diseas,...

Author(s)
Calvert, C. A.; Rawlings, C. A.
Citation
Veterinary Clinics of North America, Small Animal Practice, 1985, 15, 5, pp 991-1009

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