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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

Opioid drugs are pivotal to the effective management of acute pain in dogs, and, for this reason, they are the 'gold standard' agents for the treatment of postsurgical pain. While most veterinary surgeons will administer these drugs for the immediate post-operative period, it is less common to...

Author(s)
Murrell, J.; Flaherty, D.
Publisher
BMJ Publishing Group, London, UK
Citation
In Practice, 2014, 36, 7, pp 335...343
Abstract

Analgesia of the wide surgical excision region in surgeries such as bilateral radical mastectomy plays an important role in postoperative care. Opioids are effective in alleviating pain; however, they are sometimes difficult to obtain in most local veterinary hospitals. The objective of this...

Author(s)
Wang HuiJu; Chang ShihChieh; Lee WeiMing; Chen KuanSheng; Wang HsienChi
Publisher
Chinese Society of Veterinary Science, Taipei, Taiwan
Citation
Taiwan Veterinary Journal, 2017, 43, 3, pp 177-183
Abstract

Objective: To evaluate the analgesic potential of the centrally acting analgesics tramadol, morphine and the novel analgesic tapentadol in a pre-clinical research model of acute nociceptive pain, the tail-flick model in dogs. Study design Prospective part-randomized pre-clinical research trial....

Author(s)
Kögel, B.; Terlinden, R.; Schneider, J.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2014, 41, 3, pp 297-304
Abstract

Buprenorphine is a partial µagonist opioid used for analgesia in dogs. An extended-release formulation (ER-buprenorphine) has been shown to provide effective analgesia for 72 hr in rats and mice. Six healthy mongrel dogs were enrolled in a randomized, blinded crossover design to describe and...

Author(s)
Barletta, M.; Ostenkamp, S. M.; Taylor, A. C.; Quandt, J.; Lascelles, B. D. X.; Messenger, K. M.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 4, pp 502-512
Abstract

Surgery is the mainstay of therapy for canine and human solid cancers. Alarmingly, evidence suggests that the process of surgery may exacerbate metastasis and accelerate the kinetics of cancer progression. Understanding the mechanisms by which cancer progression is accelerated as a result of...

Author(s)
Perry, J. A.; Douglas, H.
Publisher
Saunders, An Imprint of Elsevier, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2019, 49, 6, pp 981-991
AbstractFull Text

The goal of anaesthesia in patients with neurological diseases is to maintain the homeostasis of the central nervous system, focusing on intracranial pressure and pain during the intraoperative period. The purpose of this study was to evaluate the anaesthesia performed between January 2010 and...

Author(s)
Zang, L.; Araújo, A. C. P. de; Ferreira, M. P.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2016, 44, pp 1417
Abstract

Objectives: To evaluate the effect of a prolonged constant rate infusion (CRI) of fentanyl on the minimum alveolar concentration (MAC) of isoflurane (ISOMAC) and to establish whether concurrent atropine administration influences ISOMAC in dogs. Study design: Prospective, crossover study. Animals:...

Author(s)
Simões, C. R.; Monteiro, E. R.; Rangel, J. P. P.; Nunes Junior, J. S.; Campagnol, D.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2016, 43, 2, pp 136-144
Abstract

Tramadol is administered to dogs for analgesia but has variability in its extent of absorption, which may hinder its efficacy. Additionally, the active opioid metabolite (M1) occurs in low concentrations. The purpose of this study was to determine if administration of oral tramadol with suspected...

Author(s)
KuKanich, B.; KuKanich, K.; Black, J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2017, 40, 6, pp e54-e61
Abstract

Acupuncture is recognized to induce multifactorial changes in the neuroregulatory aspects of pain physiology. Many aspects overlap with known receptor interactions of commonly used analgesic drugs, and acupuncture can increase the efficacy or replace the use of these pharmacologic pain treatments....

Author(s)
Wright, B. D.
Publisher
Saunders, An Imprint of Elsevier, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2019, 49, 6, pp 1029-1039
Abstract

Fentanyl is a potent mu opioid receptor agonist that was discovered to identify an improved human health analgesic over morphine, an opioid frequently associated with histamine-release, bradycardia, hyper- or hypotension, and prolonged postoperative respiratory depression. Historically, the...

Author(s)
Kukanich, B.; Clark, T. P.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2012, 35, s2, pp 3-19

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