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AbstractFull Text

Clinical examination, bronchoalveolar lavage fluid (BALF) cytology, acute-phase protein, and pulmonary hemostasis and fibrinolysis marker (fibrinogen, serum amyloid A [SAA], and D-dimer) results were compared between control and respiratory disease-affected horses. Using a clinical scoring system, ...

Author(s)
Barton, A. K.; Wirth, C.; Bondzio, A.; Einspanier, R.; Gehlen, H.
Publisher
Korean Society of Veterinary Science, Seoul, Korea Republic
Citation
Journal of Veterinary Science, 2017, 18, 3, pp 349-357
Abstract

The delivery of drugs to horses via the inhalation route is being increasingly adopted as a therapeutic approach in equine practice; predominantly used to treat equine lower airway disease, including, but not restricted to, severe and mild to moderate equine asthma (previously termed recurrent...

Author(s)
Pirie, R. S.; McGorum, B. C.
Publisher
BMJ Publishing Group, London, UK
Citation
In Practice, 2017, 39, 7, pp 317...327
Abstract

Severe equine asthma (EA) is the newly adopted term which defines the syndromes most recently known as recurrent airway obstruction (RAO; syn chronic obstructive pulmonary disease, Heaves) or summer pasture associated recurrent airway obstruction (SPARAO; syn summer pasture associated obstructive...

Author(s)
Pirie, R. S.
Publisher
MA Healthcare Limited, London, UK
Citation
Livestock, 2017, 22, 4, pp 208-215
Abstract

Bronchial hyper-responsiveness (BHR) describes a lung abnormality in which airways are easily triggered to constrict in response to normally harmless inhaled stimuli, and is a key element of human asthma pathophysiology. BHR contributes to equine respiratory diseases including inflammatory airway...

Author(s)
Swiderski, C. E.; Hunter, C. L.; Bowser, J. E.; Costa, L. R.; Cooley, A. J.; Claude, A.; Eddy, A. L.; Bright, L. A.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2017, 52, pp 29-35
Abstract

Mild to moderate equine asthma (EA) is the newly adopted term which defines the syndrome previously known as inflammatory airway disease (IAD). The adoption of this new nomenclature recognises the clinical phenotypic overlap amongst various non-infectious diseases of the equine lower airways; most...

Author(s)
Pirie, R. S.
Publisher
MA Healthcare Limited, London, UK
Citation
Livestock, 2017, 22, 3, pp 158-163
Abstract

OBJECTIVE: To develop a method to maintain the initial phenotype of airway smooth muscle (ASM) cells isolated from equine endobronchial biopsy specimens in long-term cell culture. SAMPLE: Endobronchial tissue specimens (8 to 10/horse) collected from the lungs of previously healthy horses at...

Author(s)
Vargas, A.; Peltier, A.; Dubé, J.; Lefebvre-Lavoie, J.; Moulin, V.; Goulet, F.; Lavoie, J. P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 3, pp 359-370
Abstract

OBJECTIVE: To evaluate the influence of respiratory tract disease (ie, recurrent airway obstruction [RAO]) and mode of inhalation on detectability of inhaled budesonide in equine plasma and urine samples. ANIMALS: 16 horses (8 healthy control horses and 8 horses affected by RAO, as determined by...

Author(s)
Barton, A. K.; Schenk, H. H. I.; Machnik, M.; Gehlen, H.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 2, pp 244-250
Abstract

Neutrophils participate in innate immunity as the first line of host defense against microorganisms. However, exacerbated neutrophil activity can be harmful to surrounding tissues; this is important in a range of diseases, including allergic asthma and chronic obstructive pulmonary disease in...

Author(s)
Borlone, C.; Morales, N.; Henriquez, C.; Folch, H.; Olave, C.; Sarmiento, J.; Uberti, B.; Moran, G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2017, 110, pp 60-64
Abstract

The aim of this study was to compare results of four different allergy tests from healthy and RAO-affected horses and to evaluate the clinical relevance of positive tested allergens via specific inhalation provocation test. Nine RAO-affected horses and 6 healthy horses underwent a complete lung...

Author(s)
Lindner, D.
Publisher
Freien Universität Berlin, Berlin, Germany
Citation
Inhalationsprovokationstest mit spezifischen Allergenen bei Pferden mit "Recurrent Airway Obstruction" (RAO), 2016, pp 128 pp.
Abstract

Equine inflammatory airway disease (IAD) and recurrent airway obstruction (RAO) represent a spectrum of chronic inflammatory disease of the airways in horses resembling human asthma in many aspects. Therefore, both are now described as severity grades of equine asthma. Increasing evidence in horses ...

Author(s)
Barton, A. K.; Gehlen, H.
Publisher
Hindawi Publishing Corporation, New York, USA
Citation
Mediators of Inflammation, 2016, 2016, pp Article ID 5693205

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