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Study suggests that even racehorses without respiratory signs could have inflammatory airway disease

Date
25 April 2018
Abstract

PICO question: In an adult horse with severe asthma (previously recurrent airway obstruction (RAO)) does using inhaled corticosteroids result in an equal improvement in clinical signs when compared to systemic corticosteroids? Clinical bottom line: The level of confidence in the outcomes from the...

Author(s)
Jocelyn, N. A.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2018, 3, 2, pp 139
Abstract

Recurrent airway obstruction (RAO), also known as heaves, is an allergic respiratory condition that develops in horses following an exposure to aeroallergens in hay and straw. This is manifested by airway hyperreactivity, inflammation, bronchoconstriction, as well as a leukocyte and platelet...

Author(s)
Iwaszko, A.; Borowicz, H.; Graczyk, S.; Slowikowska, M.; Pliszczak-Krol, A.; Niedzwiedz, A.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2018, 202, pp 172-180
AbstractFull Text

Bronchoalveolar lavage (BAL) and thoracic radiography are routinely performed diagnostic procedures. We hypothesized that BAL increases the interstitial opacity of caudoventral and caudodorsal thoracic radiographs. Fifty-three horses, including 8 clinic owned and 45 from a referral hospital...

Author(s)
Barton, A. K.; Schulze, T.; Doherr, M. G.; Gehlen, H.
Publisher
Korean Society of Veterinary Science, Seoul, Korea Republic
Citation
Journal of Veterinary Science, 2018, 19, 4, pp 563-569
Abstract

Macrophages and neutrophils are important cellular components in the process of acute inflammation and its subsequent resolution, and evidence increasingly suggests that they play important functions during the resolution of chronic, adaptive inflammatory processes. Exacerbated neutrophil activity...

Author(s)
Olave, C.; Morales, N.; Uberti, B.; Henriquez, C.; Sarmiento, J.; Ortloff, A.; Folch, H.; Moran, G.
Publisher
Springer, Dordrecht, Netherlands
Citation
Veterinary Research Communications, 2018, 42, 1, pp 57-63
Abstract

Severe equine asthma, formerly recurrent airway obstruction (RAO), is the horse counterpart of human asthma, affecting horses maintained indoors in continental climates. Equine pasture asthma, formerly summer pasture RAO, is clinically similar but affects grazing horses during hot, humid conditions ...

Author(s)
Ferrari, C. R.; Cooley, J.; Mujahid, N.; Costa, L. R.; Wills, R. W.; Johnson, M. E.; Swiderski, C. E.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Veterinary Pathology, 2018, 55, 1, pp 144-158
Abstract

Author(s)
Pickles, K.
Publisher
Veterinary Business Development Ltd, Peterborough, UK
Citation
Veterinary Times, 2018, 48, 26, pp 12-13
AbstractFull Text

Clinical examination, bronchoalveolar lavage fluid (BALF) cytology, acute-phase protein, and pulmonary hemostasis and fibrinolysis marker (fibrinogen, serum amyloid A [SAA], and D-dimer) results were compared between control and respiratory disease-affected horses. Using a clinical scoring system, ...

Author(s)
Barton, A. K.; Wirth, C.; Bondzio, A.; Einspanier, R.; Gehlen, H.
Publisher
Korean Society of Veterinary Science, Seoul, Korea Republic
Citation
Journal of Veterinary Science, 2017, 18, 3, pp 349-357
Abstract

Horses with equine respiratory tract infections that are kept in dusty environments have prolonged recovery due to increased coughing, hypersecretion of mucus, and brochoconstriction. Some authors speculate that respiratory tract infection coupled with stabling in a dusty environment may cause ...

Author(s)
Waldridge, B. M.
Publisher
John Wiley & Sons, Chichester, UK
Citation
Nutritional management of equine diseases and special cases, 2017, pp 91-96
Abstract

The goal of this study was to evaluate, if respiratory disease (Recurrent airway obstruction vs. controls) and the mode of inhalation (rest vs. exercise) influences the detectability of inhaled budesonide in equine plasma and urine samples. In 16 horses, clinical examinations, arterial blood gas...

Author(s)
Heinemann, H.
Publisher
Mensch & Buch Verlag, Berlin, Germany
Citation
Dopingrelevanz inhalativ verabreichter Glukokortikoide (Budesonid) bei Sportpferden mit COB, 2017, pp 103 pp.

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