Neointima formation and atherosclerosis are the main complications after the endovascular intervention and vascular surgery, and there are no effective drugs. Propolis is a kind of resin substance produced by honeybees and has numerous health-beneficial effects. In this study, we evaluated the...

The aim was to investigate the haematological and blood biochemistry changes of adult rabbits after two intravenous administrations of low-doses of E. coli lipopolysacharide (LPS). Six clinically healthy rabbits were distributed through a cross over design to experimental groups: Group 1 (LPS)...

Background: Traditional fermented cheese whey (TFCW), containing probiotics, has been used both as a dairy food with ethnic flavor and a medicine for cardiovascular disease, especially regulating blood lipid among Kazakh. We therefore investigated anti-atherosclerotic effects of TFCW in...

C-reactive protein (CRP), an acute phase protein in humans and rabbits, is part of the innate immune system. The role of CRP in host defense has been thought to be largely due to its ability to bind phosphocholine, activate complement, and interact with IgGRs (FcγRs). We have shown previously that...

Nicotinic acid (NA) has recently been shown to inhibit inflammatory response in cardiovascular disease. Sirtuin1 (SIRT1), a NAD⁺-dependent class III histone deacetylase, participates in the regulation of cellular inflammation. We hypothesized that dietary supplementation of NA could attenuate...

Objective: Recent advances have established a fundamental role for inflammation in mediating all stages of atherosclerosis, from initiation through progression. Quercetin may be a powerful bioactive constituent of the human diet, as a free radical scavenging agent and through interactions with...

C-reactive protein (CRP) and serum amyloid P component (SAP), which are known to increase in sera from humans and many other animals with acute inflammation caused by infection, toxic drug administration or injury, were previously purified from bovine serum. These serum levels were determined by...

A phosphorylcholine-binding protein from the haemolymph of the snail Achatina fulica was purified to near homogeneity. On SDS-PAGE the protein separated into 2 bands of 20 and 24 kDa and had a pI of 5.9. Antiserum to the protein did not cross-react to rat serum phosphorylcholine-binding protein,...

Excreted factors from Leishmania tropica and L. donovani were precipitated by human and rabbit C-reactive protein. The reaction was calcium-dependent and appeared to be similar to that reported to occur between C-reactive protein and various galactans. The absence of phosphate and N-acetyl...

A macroglobulin, haemoglobin-reactive protein, capable of precipitating with haemoglobin, was found in cattle and sheep with acute inflammatory processes. The protein migrated with immuno-globulin-M (IgM) on sucrose-density-gradient ultra-çentrifugation and on elution from Sephadex G-200 and...