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Abstract

Author(s)
Belgrave, R. L.
Publisher
Wiley-Blackwell, Ames, USA
Citation
Equine reproduction, Volume 1, 2011, Ed.2, pp 373-375
Abstract

Of the eight primary immunodeficiencies that are known or suspected to occur in horses, the most common and well characterized is severe combined immunodeficiency of Arabian foals. A genetic defect has been described that explains the lack of lymphocyte development, and the discovery of the...

Author(s)
Davis, J. L.; Jones, S. L.
Publisher
Veterinary Learning Systems Inc., Trenton, USA
Citation
Compendium on Continuing Education for the Practicing Veterinarian, 2003, 25, 7, pp 548-556
Abstract

A 10-month-old Arabian foal was evaluated for a suspected immunoglobulin (Ig) M deficiency. Decreased or nondetectable concentrations of IgM, IgA and IgG (T), and a normal concentration of IgG, were present. Results of in vitro testing of the blood lymphocyte blastogenesis showed a weak response to ...

Author(s)
Boy, M. G.; Zhang, C.; Antczak, D. F.; Hamir, A. N.; Whitlock, R. H.
Citation
Journal of Veterinary Internal Medicine, 1992, 6, 4, pp 201-205
Abstract

Author(s)
Weldon, A. D.; Zhang, C.; Antczak, D. F.; Rebhun, W. C.
Citation
Journal of the American Veterinary Medical Association, 1992, 201, 9, pp 1396-1398
Abstract

In an equine suppressor lymphocyte assay, mixed lymphocytes were exposed to lymphoblasts that had been treated with concanavalin A and concentrated on discontinuous gradients of bovine serum albumin. Suppressor cell activity was reproducibly detected in peripheral blood mononuclear cells from...

Author(s)
Perryman, L. E.; Wyatt, C. R.
Citation
Thymus, 1984, 6, 4, pp 263-272
Abstract

Author(s)
Perryman, L. E.; McGuire, T. C.
Citation
Comparative Pathology Bulletin, 1982, 14, 4, pp 3-4
Abstract

A review, mostly of work on severe combined immunodeficiency, but also considering agammaglobulinaemia and selective Igm deficiency.

Author(s)
Perryman, L. E.; Magnuson, N. S.; Bue, C. M.; Wyatt, C. R.; Riggs, M. W.
Publisher
Karger, Basel, Switzerland
Citation
Immune-deficient animals in biomedical research. 5th International Workshop on Immune-Deficient Animals, Copenhagen, October 13-16, 1985., 1987, pp 34-46
Abstract

During the foaling seasons of 1983 and 1984, 228 (76%) of 300 Arabian foals born in Poland were tested for immune system disorders by leukocyte differential counts and by measuring serum concentrations of IgM and IgG. IgM concentrations and absolute lymphocyte counts were within normal limits for...

Author(s)
Kita, J.; Frymus, T.; Crisman, M. V.; Perryman, L. E.
Citation
Journal of Equine Veterinary Science, 1985, 5, 5, pp 290-292
Abstract

Combined immunodeficiency (CID), a defect in both B and T lymphocytes, was found in 2.3% of 257 foals of Arab breeding. All affected foals died by 5 months of age. The belief that CID is transmitted as an autosomal recessive genetic defect was supported by results from matings of dams and sires...

Author(s)
Poppie, M. J.; McGuire, T. C.
Citation
Journal of the American Veterinary Medical Association, 1977, 170, 1, pp 31-33
Datasheet

Information in this disease system overview will be expanded in the next edition of the Compendium. Please note that the list of diseases affecting...

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