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AbstractFull Text

Periodontal disease is a common condition, related to the entrapment of food in non-physiological diastemas in horses. Treatment consists of correction of the primary cause, cleansing and debridement of the gingival sulcus, called Conventional Therapy (CT). Often antimicrobials are requested due to ...

Author(s)
Dias, L. L. R.; Guerreiro, J. C.; Gandini, J. C.; Grolli, K.; Bruschi, M. L.; Ribeiro, M. G.
Publisher
FEPMVZ - Editora, Belo Horizonte, Brazil
Citation
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020, 72, 5, pp 1599-1608
Abstract

Photodynamic therapy (PDT) holds great promise in treating veterinary and human dermatological neoplasms, including equine sarcoids, but is currently hindered by the amount of photosensitiser and light that can be delivered to lesions thicker than around 2 mm, and by the intrinsic antioxidant...

Author(s)
Golding, J. P.; Kemp-Symonds, J. G.; Dobson, J. M.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2017, 15, 4, pp 1543-1552
Abstract

Objective: (i) To report the successful treatment of 10 cases of equine periocular squamous cell carcinoma (PSCC) with surgical excision and photodynamic therapy (PDT) using verteporfin. (ii) To evaluate time to first tumor recurrence between PDT-treated horses and horses treated with surgical...

Author(s)
Giuliano, E. A.; Johnson, P. J.; Delgado, C.; Pearce, J. W.; Moore, C. P.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Ophthalmology, 2014, 17, s1, pp 37-45
Abstract

Photodynamic therapy (PDT) is an evolving method of treating superficial tumours that is non-invasive and carries minimal risk of toxicity. It combines tumour-selective photosensitiser dyes, tissue oxygen and targeted illumination to generate cytotoxic reactive oxygen species (ROS) within the...

Author(s)
Dobson, J.; Queiroz, G. F. de; Golding, J. P.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2018, 233, pp 8-18
Abstract

Objective: Local photodynamic therapy (PDT) is a novel cancer therapy in veterinary ophthalmology. A prospective pilot study seeking to demonstrate proof of principle and safety for the treatment of equine periocular squamous cell carcinoma (PSCC) was therefore conducted. We hypothesized that...

Author(s)
Giuliano, E. A.; MacDonald, I.; McCaw, D. L.; Dougherty, T. J.; Klauss, G.; Ota, J.; Pearce, J. W.; Johnson, P. J.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Veterinary Ophthalmology, 2008, 11, s1, pp 27-34
AbstractFull Text

Sarcoids are reported as the most common tumour of the horse, localized of the skin, that do not metastasize and rarely regress spontaneously. Treatment described in veterinary literature includes surgical excision, cryotherapy, radio-therapy (low-dose-rate or high dose rate brachytherapy with...

Author(s)
Igna, C.; Zaha, C.
Publisher
University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania
Citation
Scientific Works. Series C. Veterinary Medicine, 2021, 67, 2, pp 65-72
Abstract

The case report describes the surgical and photodynamic treatment (PDT) of an equine sarcoid in a 6-year-old gelding. A mass on the ventral prepuce, several tumours on the lateral aspect of the prepuce and one sarcoid on the front aspect of the chest were treated. For PDT, Temoporfin (Fospeg®...

Author(s)
Reschke, C.
Publisher
Schattauer GmbH, Stuttgart, Germany
Citation
Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2012, 40, 5, pp 309-313
Abstract

Successful treatment of naturally occurring periocular squamous cell carcinoma (SCC) in horses with photodynamic therapy (PDT) has been performed by injecting residual tumor with verteporfin and applying laser irradiation immediately following injection. This study used a murine model to evaluate...

Author(s)
Barnes, L. D.; Giuliano, E. A.; Ota, J.; Cohn, L. A.; Moore, C. P.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Journal, 2009, 180, 1, pp 60-65
Abstract

The treatment of periorbitol equine sorcoids can be challenging for practitioners and owners as well. As reported for equine sorcoids in general, tumor growth is independent from gender and can affect horses of all ages. Furthermore the pathogenesis can be multifactoriol and all six types reported...

Author(s)
Marginfer, D.; Toth, J.; Buijs, L.; Gehlen, H.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2021, 37, 3, pp 267-277
Abstract

The objective of this study was to evaluate the effect of local photodynamic therapy (PDT) with verteporfin on tumor growth inhibition of squamous cell carcinoma (SCC) in a murine model. SCC was implanted in 85 nude mice by subcutaneous injection of A-431 SCC cells. Treatment groups (10 mice/group) ...

Author(s)
Ota, J.; Giuliano, E. A.; Cohn, L. A.; Lewis, M. R.; Moore, C. P.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Journal, 2008, 176, 2, pp 170-176

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