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Abstract

Motor neuron disease (MND) is a spontaneous neurologic disorder of humans and adult horses, which results from the degeneration of motor neurons in the spinal cord and brain stem. The etiology of MND disease in the South Asian region is not well understood. To achieve the objective of the study,...

Author(s)
Shakeela Daud; Nisar Ahmed; Sara Naudhani; Muhammad Younus; Saba Manzoor; Sehrish Firyal; Tahir Yaqub; Hashmi, A. S.; Riaz-ul-Amin; Muhammad Wasim; Sajid Umar
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2018, 62, pp 60-65
Abstract

Neurofilaments (NFs) are structural proteins of neurons that are released in significant quantities in the cerebrospinal fluid and blood as a result of neuronal degeneration or axonal damage. Therefore, NFs have potential as biomarkers for neurologic disorders. Neural degeneration increases with...

Author(s)
Gómez, A. M. M.; Zhu, S.; Palmer, S.; Olsen, E.; Ness, S. L.; Divers, T. J.; Bischoff, K.; Mohammed, H. O.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 125, pp 1-6
Abstract

Objective: A pigment retinopathy has been reported in adult horses with equine motor neuron disease (EMND) arising from chronic α-tocopherol (α-TP) deficiency. A pigment retinopathy has not been identified in horses with neuroaxonal dystrophy/equine degenerative myeloencephalopathy (NAD/EDM) that...

Author(s)
Finno, C. J.; Kaese, H. J.; Miller, A. D.; Gianino, G.; Divers, T.; Valberg, S. J.
Publisher
Wiley, Boston, USA
Citation
Veterinary Ophthalmology, 2017, 20, 4, pp 304-309
Abstract

We carried out an investigation to identify the factors that predispose to the risk of equine motor neuron disease (EMND) and evaluated the long-term impact of an intervention. Data on several biomarkers, including antioxidants (α-tocopherols, β-carotenes, glutathione peroxidase (GSHPx)), and...

Author(s)
Banfield, J.; Lisak, R.; Omar, A.; Domingos, W.; Fiaschitello, A.; Morales-Gomez, A.; Divers, T. J.; Mohammed, H. O.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2019, 77, pp 132-138
Abstract

Background: Equine motor neuron disease (EMND) is a neuromuscular disorder that affects adult horses. Although EMND has been linked to vitamin E deficiency, its etiopathogenesis is poorly understood. Objectives: To describe clinical features, laboratory results, and postmortem findings in a series...

Author(s)
Díez de Castro, E.; Zafra, R.; Acevedo, L. M.; Pérez, J.; Acosta, I.; Rivero, J. L. L.; Aguilera-Tejero, E.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2016, 30, 3, pp 873-879
Abstract

Equine motor neuron disease (EMND) is a condition characterised by generalised weakness and muscle atrophy associated with degeneration of motor neurons in the ventral horns of the spinal cord. Despite the frequent detection of cranial nerve nuclei pathology during post mortem examination,...

Author(s)
Robin, M.; Malbon, A.; Ricci, E.; McGowan, C.; Malalana, F.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Education, 2016, 28, 8, pp 434-438
Abstract

In this study, fasciculation of the limbs and tongue was observed in four horses kept by a riding club. Neurogenic muscle atrophy was also observed in biopsy of pathological tissues. In addition, in two cases that subjected to autopsy, Bunina-like bodies of inclusion in the cell bodies of neurons...

Author(s)
Sasaki, N.; Imamura, Y.; Sekiya, A.; Itoh, M.; Furuoka, H.
Publisher
Japanese Society of Equine Science (Nihon Uma Kagakukai) Equine Research Institute, Japan Racing Association, Utsunomiya, Japan
Citation
Journal of Equine Science, 2016, 27, 3, pp 119-124
Abstract

Equine motor neuron disease (EMND) is a neurodegenerative disease caused by an oxidative disorder that affects the lower somatic motor neurons and is associated with low plasma concentration of vitamin E. The disease is characterized by degeneration of motor neurons (MN) in the ventral horn of the...

Author(s)
Nóbrega, F. S.; Zoppa, A. L. do V. de; Ferreira, M. P.; Stopiglia, A. J.
Publisher
Pontificia Universidade Católica do Paraná, Paraná, Brazil
Citation
Revista Acadêmica Ciências Agrárias e Ambientais, 2013, 11, 2, pp 205-211
Abstract

Reasons for performing study: Reference values for quantitative electromyography (QEMG) in shoulder and hindlimb muscles of horses are limited. Objectives: To determine normative data on QEMG analysis of supraspinatus (SS), infraspinatus (IS), deltoideus (DT) and biceps femoris (BF) muscles. Study...

Author(s)
Jose-Cunilleras, E.; Wijnberg, I. D.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Journal, 2016, 48, 2, pp 234-239
Abstract

Equine degenerative myeloencephalopathy (EDM) is characterized by a symmetric general proprioceptive ataxia in young horses, and is likely underdiagnosed for 2 reasons: first, clinical signs overlap those of cervical vertebral compressive myelopathy; second, histologic lesions - including axonal...

Author(s)
Finno, C. J.; Valberg, S. J.; Shivers, J.; D'Almeida, E.; Armién, A. G.
Publisher
American College of Veterinary Pathologists Inc., Lawrence, USA
Citation
Veterinary Pathology, 2016, 53, 1, pp 77-86

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