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Abstract

Background: Chronic progressive lymphoedema (CPL) is a disabling condition affecting various draft horse breeds, including Friesian horses. Hypothesis: The high incidence of CPL in Friesian horses suggests a genetic component and a predisposing phenotype. Animals: For the genomic study, 26 affected ...

Author(s)
Affolter, V. K.; Dalley, B.; Kass, P. H.; Brown, E. A.; Sonder, C.; Bannasch, D. L.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2020, 31, 3, pp 234-e51
Abstract

C-X-C motif ligand 10 (CXCL10) is a pro-inflammatory chemokine and has been extensively evaluated in people and mice. In horses, CXCL10 and its involvement in host immunity has rarely been analyzed due to the lack of specific antibodies. We generated a mAb specific for the equine chemokine CXCL10...

Author(s)
Schnabel, C. L.; Babasyan, S.; Freer, H.; Wagner, B.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2019, 207, pp 25-30
Abstract

Rheumatoid factor (RF) is used in human and veterinary medicine in the form of IgM RF traditionally to support the diagnosis of rheumatoid arthritis (RA). In the latest diagnostic criteria, presence of anti-citrullinated protein antibodies (ACPA) was added to the grading system for the diagnosis of ...

Author(s)
Hoikhman, R.; Kudlackova, H.; Babak, V.; Faldyna, M.; Jahn, P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2018, 202, pp 141-146
Abstract

Diagnosis of chronic progressive lymphoedema (CPL) in draught horses, including the Belgian Draught Horse, is mainly based on clinical evaluation of typical lower limb lesions. A deficient perilymphatic elastic support, caused by a pathological elastin degradation in skin and subcutis, has been...

Author(s)
Keyser, K. de; Berth, M.; Christensen, N.; Willaert, S.; Janssens, S.; Ducatelle, R.; Goddeeris, B. M.; Cock, H. E. V. de; Buys, N.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2015, 163, 1/2, pp 16-22
Abstract

OBJECTIVE: To develop a method to maintain the initial phenotype of airway smooth muscle (ASM) cells isolated from equine endobronchial biopsy specimens in long-term cell culture. SAMPLE: Endobronchial tissue specimens (8 to 10/horse) collected from the lungs of previously healthy horses at...

Author(s)
Vargas, A.; Peltier, A.; Dubé, J.; Lefebvre-Lavoie, J.; Moulin, V.; Goulet, F.; Lavoie, J. P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 3, pp 359-370
Abstract

Spinal cord disorders are a common problem in equine medicine. However, finding the site of the lesion is challenging for veterinarians because of a lack of sensitive diagnostic methods that can assess neuronal functional integrity in horses. Although medical imaging is frequently applied to help...

Author(s)
Journée, S. L.; d'Argenteuil, C. de M.; Maré, L. de; Boshuizen, B.; Vanderperren, K.; Journée, L. H.; Bruijn, M. de; Bergmann, W.; Delesalle, C.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2019, 81, pp 102790
Abstract

Only few quantitative reports exist about the concentrations and induction of immunoglobulin A (IgA) in mucosal secretions of horses. Despite this, it is widely assumed that IgA is the predominant immunoglobulin on mucosal surfaces in the horse. Here, two new monoclonal antibodies (mAbs) against...

Author(s)
Schnabel, C. L.; Babasyan, S.; Freer, H.; Wagner, B.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2017, 188, pp 12-20
Abstract

Tissue damage caused by oxidative stress is involved in the pathogenesis of several diseases in animals and man, and is believed to play a role in the development of laminitis in horses. The aim of this study was to investigate the oxidative stress associated with laminar lesions in horses with...

Author(s)
Laskoski, L. M.; Dittrich, R. L.; Valadão, C. A. A.; Brum, J. S.; Brandão, Y.; Brito, H. F. V.; Sousa, R. S. de
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2016, 171, pp 66-72
Abstract

This study was undertaken to assess the effects of T. equi infection on serum concentrations of some important cytokines including interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), and interleukin-1 beta (IL-1β), IL-1α, IL-4, IL-6, IL-8, IL-10, IL-12α, IL-12β, IL-18, as well as total, protein...

Author(s)
Mostafavi, E.; Esmaeilnejad, B.; Foroushani, S. M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Comparative Immunology, Microbiology & Infectious Diseases, 2020, 70,
Abstract

Endotoxemia represents a significant clinical and economic problem for the equine industry. This study assesses the kinetics of soluble CD14 (sCD14), chemokine (C C motif) ligand 2 (CCL2), interleukin 10 (IL-10) and plasma procalcitonin (PCT) in healthy horses after the intravenous infusion of...

Author(s)
Bonelli, F.; Meucci, V.; Divers, T. J.; Wagner, B.; Intorre, L.; Sgorbini, M.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2017, 184, pp 29-35

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