Cookies on VetMed Resource

Like most websites we use cookies. This is to ensure that we give you the best experience possible.

 

Continuing to use www.cabi.org  means you agree to our use of cookies. If you would like to, you can learn more about the cookies we use.

VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

Sign up to receive our Veterinary & Animal Sciences e-newsletter, book alerts and offers direct to your inbox.

Results per page:

Search results

Abstract

OBJECTIVE: To determine the effect of dantrolene premedication on various cardiovascular and biochemical variables and recovery in isoflurane-anesthetized horses. ANIMALS: 6 healthy horses. PROCEDURES: Each horse was anesthetized twice with a 21- to 28-day washout period between anesthetic...

Author(s)
McKenzie, E. C.; Concetto, S. di; Payton, M. E.; Mandsager, R. E.; Arko, M.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2015, 76, 4, pp 293-301
Abstract

Reasons for performing study: Dantrolene sodium is used to prevent exertional rhabdomyolysis in predisposed horses. Food intake might negatively impact dantrolene bioavailability in horses; however, prolonged feed restriction might be detrimental to performance. Objective: To determine a minimum...

Author(s)
McKenzie, E. C.; Garrett, R. L.; Payton, M. E.; Riehl, J. H.; Firshman, A. M.; Valberg, S. J.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Equine Veterinary Journal, 2010, 42, s38, pp 613-617
Abstract

Dantrolene is a skeletal muscle relaxant used commonly in performance horses to prevent exertional rhabdomyolysis. The goal of the study reported here was to begin to characterize cytochrome P450-mediated metabolism of dantrolene in the horse and describe the pharmacokinetics of the compound,...

Author(s)
Knych, H. K. D.; Arthur, R. M.; Taylor, A.; Moeller, B. C.; Stanley, S. D.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2011, 34, 3, pp 238-246
Abstract

Objective: To determine the effect of oral administration of dantrolene sodium on serum creatine kinase (CK) activity after exercise in horses with recurrent exertional rhabdomyolysis (RER). Animals: 2 healthy horses and 5 Thoroughbreds with RER. Procedure: 3 horses received 2 doses of dantrolene...

Author(s)
McKenzie, E. C.; Valberg, S. J.; Godden, S. M.; Finno, C. J.; Murphy, M. J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2004, 65, 1, pp 74-79
Abstract

Reasons for performing study: Dantrolene sodium (Dantrium) has been used extensively for the treatment of myopathies in man and anecdotal evidence suggests it is of clinical benefit in the control of exercise-induced rhabdomyolysis (ER) in racehorses, although data to support this are currently...

Author(s)
Edwards, J. G. T.; Newton, J. R.; Ramzan, P. H. L.; Pilsworth, R. C.; Shepherd, M. C.
Publisher
Equine Veterinary Journal Ltd, Newmarket, UK
Citation
Equine Veterinary Journal, 2003, 35, 7, pp 707-711
Abstract

The apicomplexan parasite Sarcocystis neurona is the primary etiologic agent of equine protozoal myeloencephalitis (EPM), a serious neurologic disease of horses. Many horses in the U.S. are at risk of developing EPM; approximately 50% of all horses in the U.S. have been exposed to S. neurona and...

Author(s)
Bowden, G. D.; Land, K. M.; O'Connor, R. M.; Fritz, H. M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
International Journal for Parasitology: Drugs and Drug Resistance, 2018, 8, 1, pp 137-144
Abstract

Muscular disorders rank among the most prevalent problems of horses competing in a broad variety of athletic disciplines, including track racing, dressage, endurance racing and Western riding disciplines. As described in this review, active scientific investigation is continuing to elucidate the...

Author(s)
McKenzie, E.
Publisher
Wageningen Academic Publishers, Wageningen, Netherlands
Citation
Comparative Exercise Physiology, 2017, 13, 3, pp 175-183
Abstract

Dysfunctional skeletal muscle calcium homeostasis plays a central role in the pathophysiology of several human and animal skeletal muscle disorders, in particular, genetic disorders associated with ryanodine receptor 1 (RYR1) mutations, such as malignant hyperthermia, central core disease,...

Author(s)
Fernandez-Fuente, M.; Terracciano, C. M.; Martin-Duque, P.; Brown, S. C.; Vassaux, G.; Piercy, R. J.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 8, pp e105971
AbstractFull Text

Author(s)
Knych, H. K. D.; Arthur, R. M.; Taylor, A.; Moeller, B. C.; Stanley, S. D.
Publisher
American Association of Equine Practitioners (AAEP), Lexington, USA
Citation
Proceedings of the 56th Annual Convention of the American Association of Equine Practitioners, Baltimore, Maryland, USA, 4-8 December 2010, 2010, pp 53
Abstract

Author(s)
Holmes, M. A.
Publisher
Equine Veterinary Journal Ltd, Newmarket, UK
Citation
Equine Veterinary Education, 2007, 19, 2, pp 97-99

Refine Results

Sort Order
Author
Geographical Location
Item Type
Language
Organisms
Subject Topics

Datasheet Filter