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Abstract

The highly selective breeding of Arabian horses results in inbreeding depression and genetic disorders, thereby causing significant economic loss. The Polish population of Arabians has a great impact on many breeding programmes. The aim of the current study was to monitor genetic variants involved...

Author(s)
Bugno-Poniewierska, M.; Stefaniuk-Szmukier, M.; Piestrzyńska-Kajtoch, A.; Fornal, A.; Piórkowska, K.; Ropka-Molik, K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2019, 248, pp 71-73
Abstract

Severe combined immunodeficiency (SCID) is a fatal genetic disorder and one of the common genetic diseases of the Arabian horse. The genetic mutation responsible for this disease is a five base pair deletion (TCTCA) in the DNA-protein kinase catalytic subunit gene. Severe combined immunodeficiency...

Author(s)
El-Ela, N. A. A.; El-Nesr, K. A.; Ahmed, H. A.; Brooks, S. A.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2018, 68, pp 55-58
Abstract

Common variable immunodeficiency (CVID) is a rare condition in adult horses characterized by hypogammaglobulinemia and increased susceptibility to parasitic and bacterial infections, including recurrent respiratory diseases, septicemia, and meningitis. Lyme disease is often included as a...

Author(s)
Pecoraro, H. L.; Felippe, M. J. B.; Miller, A. D.; Divers, T. J.; Simpson, K. W.; Guyer, K. M.; Duhamel, G. E.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2019, 31, 2, pp 241-245
Abstract

Background: The carrier status of lavender foal syndrome (LFS), cerebellar abiotrophy (CA), severe combined immunodeficiency (SCID), and occipitoatlantoaxial malformation (OAAM1) in foals with juvenile idiopathic epilepsy (JIE) is unknown. Hypothesis/Objectives: To determine the carrier status of...

Author(s)
Aleman, M.; Finno, C. J.; Weich, K.; Penedo, M. C. T.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2018, 32, 1, pp 465-468
AbstractFull Text

Severe Combined Immunodeficiency (SCID) is a lethal and autosomal recessive hereditary disorder, which has frequently been reported in Arabian horses, dogs, mice and humans. The genetic basis of equine SCID is 5-base pairs deletion in the DNA-dependent protein kinase catalytic subunit (DNA-PKcs)...

Author(s)
Kul, B. Ç.; Ağaoğlu, Ö. K.; Ertuğrul, O.; Durmaz, M.
Publisher
Ankara Üniversitesi, Veteriner Fakültesi Dekanlığ, Ankara, Turkey
Citation
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2014, 61, 1, pp 59-63
Abstract

Hepacivirus A (also known as nonprimate hepacivirus and equine hepacivirus) is a hepatotropic virus that can cause both transient and persistent infections in horses. The evolution of intrahost viral populations (quasispecies) has not been studied in detail for hepacivirus A, and its roles in...

Author(s)
Ramsay, J. D.; Evanoff, R.; Mealey, R. H.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Journal of Virology, 2018, 92, 18, pp e00314-18
Abstract

Understanding the dynamics of acute viral infection is crucial for developing strategies to prevent and control infection. In this study, lentiviral dynamics in a host without adaptive immunity were examined in order to determine kinetic parameters of infection and quantify the effect of...

Author(s)
Schwartz, E. J.; Vaidya, N. K.; Dorman, K. S.; Carpenter, S.; Mealey, R. H.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Virology, 2018, 513, pp 108-113
Abstract

A total of 17 microsatellite deoxyribonucleic acid loci used routinely for horse parentage control were used to evaluate genetic diversity among normal Arabian horses and severe combined immunodeficiency (SCID) carrier Arabian horses (ArS) and normal Arab-Barb horses and SCID carrier Arab-Barb ...

Author(s)
Piro, M.; Benjouad, A.; Karom, A.; Nabich, A.; Benbihi, N.; El-Allali, K.; Machmoum, M.; Ouragh, L.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2011, 31, 11, pp 618-624
AbstractFull Text

SCID is a lethal genetic autosomal recessive disorder that has been observed in humans, dogs, mice, and horses. Affected animals are incapable of generating specific antigens for immune responses needed to protect them from infectious diseases. The frequency of affected recessive allele varies in...

Author(s)
Arbani, R. S.; Tarang, A.; Rafeie, F.; Potki, P.; Seighalani, R.; Baniyaghoub, S.; Vahidi, M. F.; Ajamian, F.
Publisher
Tarbiat Modares University, Tehran, Iran
Citation
Journal of Agricultural Science and Technology, 2015, 17, 3, pp 615-622
Abstract

This chapter reviews some basic concepts of genetics and describes those ocular conditions for which a genetic basis is known or suspected in the horse. These include congenital stationary night blindness (CSNB) and multiple congenital ocular anomalies (MCOA) syndrome, for which causative mutations ...

Author(s)
Sandmeyer, L. S.; Bellone, R.
Publisher
John Wiley & Sons, Chichester, UK
Citation
Equine opthalmology, 2017, pp 545-566

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