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Abstract

Background: Equine endometrosis is a chronic degenerative condition, described as endometrial fibrosis that forms in the stroma, under the basement membrane and around the endometrial glands. The role of lysophosphatidic acid (LPA) in the development of tissue fibrosis varies depending on the...

Author(s)
Szóstek-Mioduchowska, A.; Leciejewska, N.; Zelmanska, B.; Staszkiewicz-Chodor, J.; Ferreira-Dias, G.; Skarzynski, D.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2020, 16, 343, pp (17 September 2020)
Abstract

Equine endometrosis (endometrial fibrosis) is a degenerative chronic process that occurs in the uterus of the mare and disturbs proper endometrial function. Fibrosis is attributed to excessive deposition of extracellular matrix (ECM) components. The turnover of ECM is mediated by matrix...

Author(s)
Szóstek-Mioduchowska, A. Z.; Baclawska, A.; Okuda, K.; Skarzynski, D. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Cytokine, 2019, 123, pp Article 154767
Abstract

Equine endometrosis is a multifactorial chronic degenerative condition, considered to be one of a major causes of equine infertility. The formation of periglandular fibrosis seems to be linked to chronic inflammation of the mare endometrium in a paracrine way and in a response to numerous forms of...

Author(s)
Domino, M.; Jasinski, T.; Kautz, E.; Juszczuk-Kubiak, E.; Ferreira-Dias, G.; Zabielski, R.; Sady, M.; Gajewski, Z.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2020, 147, pp 18-24
Abstract

Neutrophil extracellular traps (NETs) are DNA complexes carrying nuclear and cytoplasmic proteins, such as elastase (ELA), cathepsin-G (CAT) and myeloperoxidase (MPO). Mare endometrosis is a chronic degenerative process characterized by excessive collagen in endometrium. While NETs fight bacteria...

Author(s)
Rebordão, M. R.; Amaral, A.; Lukasik, K.; Szóstek-Mioduchowska, A.; Pinto-Bravo, P.; Galvão, A.; Skarzynski, D. J.; Ferreira-Dias, G.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2018, 113, pp 8-18
Abstract

Endometrosis is a chronic degenerative disease of the mare's endometrium characterized by the presence of collagen fibers. Besides several causes, such as recurrent endometritis, endometrosis has been highly related to mare aging. Biopsy of mare endometrium has been used either as a diagnostic tool ...

Author(s)
Pinto-Bravo, P.; Rebordão, M. R.; Amaral, A.; Fernandes, C.; Cuello, C.; Parrilla, I.; Martínez, E.; Costa, R. P. R. da; Skarzynski, D. J.; Ferreira-Dias, G.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2018, 34, 1, pp 43-46
Abstract

Chronic degenerative endometritis (CDE) is an important cause of fertility problems in older mares. It is estimated that 30% of mares breeding are over 18 years old and the high value of their progeny encourages the use of these animals in assisted reproduction procedures. Currently, cell-based...

Author(s)
Alvarenga, M. A.; Carmo, M. T. do; Segabinazzi, L. G.; Guastali, M. D.; Maia, L.; Landim-Alvarenga, F. C.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2016, 42, pp 12-18
AbstractFull Text

Patency of the cervix of the mare is considered to be a prerequisite for efficient uterine drainage after mating. Endometriosis, also known as chronic degenerative endometritis, is described a periglandular and/or stromal endometrial fibrosis, including glandular alteration in fibrotic foci. ...

Author(s)
Liepina, E.; Antane, V.
Publisher
Latvia University of Agriculture, Faculty of Veterinary Medicine, Jelgava, Latvia
Citation
Starptautiskās zinātniskās konferences RAKSTI, Dzīvnieki. Veselība. Pārtikas higiena., Jelgava, 2010. gada 29. oktobrī, 2010, pp 73-77
Abstract

Endometrosis is a degenerative chronic process, characterized by paramount fibrosis development in mare endometrium. This condition is one of the major causes of subfertility/infertility in mares. As in other organs, fibrosis might be a pathologic sequel of many chronic inflammatory diseases....

Author(s)
Rebordão, M. R.; Galvão, A.; Szóstek, A.; Amaral, A.; Mateus, L.; Skarzynski, D. J.; Ferreira-Dias, G.
Publisher
Wiley-Blackwell, Berlin, Germany
Citation
Reproduction in Domestic Animals, 2014, 49, s4, pp 82-87
Abstract

Chronic degenerative changes to the endometrium include endometrial fibrosis, involving a deposition of fibrous tissue in the endometrial stroma and around the endometrial glands. In this study it is hypothesised that endometrial fibrosis is a result of extracellular matrix (ECM) remodelling...

Author(s)
Oddsdóttir, C.; Riley, S. C.; Leask, R.; Edwards, D. R.; Watson, E. D.
Publisher
Hippiatrika Verlagsgesellschaft mbH, Stuttgart, Germany
Citation
Pferdeheilkunde, 2008, 24, 1, pp 70-73
Abstract

Chronic degenerative disease of the mare's endometrium is characterised by changes in the uterine glands, including cystic dilation, hyperplasia and periglandular fibrosis. Endometrial biopsies were taken from 23 mares with different grades of endometrial degeneration. Solid structures were...

Author(s)
Walter, I.; Helmreich, M.; Handler, J.; Aurich, C.
Publisher
British Veterinary Association, London, UK
Citation
Veterinary Record, 2003, 153, 23, pp 708-710

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