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Abstract

Hospitalized pregnant mares being held nil per os (PO) because of medical or surgical events present a dilemma for pregnancy maintenance therapy, which commonly includes oral altrenogest. Rectal administration of medications is a recognized route for achieving systemic concentrations, but there are ...

Author(s)
Ellis, K. E.; Council-Troche, R. M.; Dollen, K. A. von; Beachler, T. M.; Bailey, C. S.; Davis, J. L.; Lyle, S. K.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2019, 72, pp 41-46
Abstract

Altrenogest (Regu-Mate®) is labelled for daily oral administration and is used in mares to suppress estrus behavior, maintain pregnancy and synchronize estrous cycles. It is a very potent progestin, with potential risks associated with transdermal absorption for persons handling or administering...

Author(s)
Hornberger, K.; Lyman, C. C.; Baldrighi, J. M.; Holyoak, G. R.
Publisher
The Society for Theriogenology, Montgomery, USA
Citation
Clinical Theriogenology, 2019, 11, 1, pp 59-65
AbstractFull Text

The main objective of this study was to investigate efficacy of artificial lighting and timing of altrenogest treatment for hastening the ovulation in Thoroughbred mares. 106 Thoroughbred mares had different follicle sizes (< 30 mm) was evaluated under four groups. Mares undergoing only reproductive examination were control group Group I (n = 18). The mares has less than 30 mm in diameter folicle applied oral altrenogest (0.044 mg/bw, for 10 days) were grouped according to the month...

Author(s)
Tek, H. B.
Publisher
Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Porto Alegre, Brazil
Citation
Acta Scientiae Veterinariae, 2019, 47,
Abstract

The objective of this study is to follow up the follicular growth in ovaries until mating by ultrasonography to determine of pregnancy rates, serum estrogen, progesterone, AMH and IGF-1 concentrations in mares which synchronized with altrenogest and to compare the obtained data with non-lactating...

Author(s)
Polat, I. M.; Korkmaz, Ö.; Elifoğlu, T. B.; Yağcı, I. P.; Çolakoğlu, H. E.; Pekcan, M.
Publisher
Erciyes University, Faculty of Veterinary Medicine, Kayseri, Turkey
Citation
Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 2020, 17, 1, pp 63-67
Abstract

To date, there has been limited research on manipulation of the estrous cycle in endangered equids. The objectives of this study were to assess the efficacy of using combinations of: (a) oral altrenogest and PGF2α, and (b) injectable altrenogest and PGF2α for manipulation of ovarian activity in...

Author(s)
Collins, C. W.; Monfort, S. L.; Vick, M. M.; Wolfe, B. A.; Weiss, R. B.; Keefer, C. L.; Songsasen, N.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Animal Reproduction Science, 2014, 148, 1/2, pp 42-52
Abstract

Synthetic progestins, including altrenogest, are employed to modify undesirable estrus-related behavior or poor performance in mares. Bilateral laparoscopic ovariectomy (BLO) is another means of management. Our objective was to compare the perceived improvement in mares with estrus-related problems ...

Author(s)
Roessner, H. A.; Kurtz, K. A.; Caron, J. P.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2015, 35, 3, pp 250-253
Abstract

Altrenogest, a synthetic progestogen, is characterized by its estrus synchronization in mares, ewes, sows, and gilts. To investigate the pharmacokinetic profile and evaluate its accumulation in gilts, 18 oral doses of 20 mg altrenogest/gilt/day were given to eight healthy gilts at an interval of 24 ...

Author(s)
Xiao HongZhi; Sun Pan; Sun FeiFei; Qiu JiCheng; Wang Jie; Wang JianZhong; Lin YaLong; Gong XiaoHui; Zhang Lu; Zhang SuXia; Cao XingYuan
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2019, 42, 6, pp 660-664
Abstract

Treatment with the progestin altrenogest is widely used in pregnant mares. The fact that foals born from healthy mares treated with altrenogest until term suffered from neonatal problems raises the question of direct effects of altrenogest on vital functions in the neonate. We have therefore...

Author(s)
Palm, F. M.; Schenk, I.; Neuhauser, S.; Schubert, D.; Machnik, M.; Schänzer, W.; Aurich, C.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2010, 74, 2, pp 229-235
Abstract

During the latter half of gestation in mares, there is a complex milieu of pregnanes in peripheral blood. Progesterone concentrations are often assessed by immunoassay during late gestation as a measure of pregnancy well-being; however, interpretation of results is complicated by the numerous...

Author(s)
Wynn, M. A. A.; Esteller-Vico, A.; Legacki, E. L.; Conley, A. J.; Loux, S. C.; Stanley, S. D.; Curry, T. E., Jr.; Squires, E. L.; Troedsson, M. H.; Ball, B. A.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2018, 106, pp 127-133
Abstract

Endogenous progesterone levels may decline after transcervical embryo transfer in some mares. Progestogen therapy is commonly used to support endogenous progesterone levels in embryo transfer recipient mares or those carrying their own pregnancy. The goal of this study was to determine the effects...

Author(s)
DeLuca, C. A.; McCue, P. M.; Patten, M. L.; Squires, E. L.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2011, 31, 2, pp 57-62

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