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Abstract

Objective: To investigate the pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs. Study design: Prospective crossover study. Animals: A group of six healthy male Dunkin Hartley guinea pigs. Methods: A single dose of meloxicam (1.5 mg kg-1) was administered orally and...

Author(s)
Moeremans, I.; Devreese, M.; Baere, S. de; Croubels, S.; Hermans, K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 4, pp 548-555
Abstract

Objective: To study the pharmacokinetic properties of Fufang Baijiezi Gel (FBG) after different acupoints administration. Methods: Sinapine thiocyanate, tetrahydro-palmatine, 6-gingerol, and asarinin, which were four substances of FBG, were determined by a sensitive liquid chromatography tandem...

Author(s)
Wang GuoHua; Zhang BaoXian; Nie QiXia; Zang Chen; Zhu Qiong
Publisher
Tianjin Press, Tianjin, China
Citation
Chinese Herbal Medicines, 2015, 7, 4, pp 365-370
Abstract

The decoction of Pheretima aspergillum is used as a traditional medicine for treatment of asthma in China with a long clinical history. The aim of the study was to investigate the anti-asthma activities of an active components group obtained from the decoction of Pheretima aspergillum in histamine...

Author(s)
Shi QingXin; Wang XuanYuan; Liu JunYi; Xiang XingLiang; Su MingWu; Huang RongZeng; Song ChengWu
Publisher
School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
Citation
Iranian Journal of Pharmaceutical Research, 2019, 18, 2, pp 867-876
Abstract

The objectives of this study were to investigate quantitative alterations in leukocytes and immunosuppressive effects of ginger rhizome associated with oral administration of Azathioprine (AZA) on guinea pig model. This study was carried out at the Al Jouf University during the period from March to ...

Author(s)
Almarshad, H. A.
Publisher
Academic Journals, Nairobi, Kenya
Citation
African Journal of Pharmacy and Pharmacology, 2014, 8, 41, pp 1066-1070
Abstract

Zingiber officinale is used for the management of fever, bronchial asthma and cough for thousands of years. While the link to a particular indication has been established in human, the active principle of the formulation remains unknown. Herein, we have investigated a water extracted...

Author(s)
Bera, K.; Nosalova, G.; Sivova, V.; Ray, B.
Publisher
Wiley-Blackwell, Chichester, UK
Citation
Phytotherapy Research, 2016, 30, 1, pp 105-111
Abstract

Blockade of potassium channels with 4-aminopyridine (4-AP) restores conduction to demyelinated axons and improves function. Unfortunately, 4-AP causes adverse effects and its clinical effects are unpredictable and limited. Derivatives of 4-AP have been tested in models of spinal cord injury in ...

Author(s)
Olby, N. J.; Smith, D. T.; Humphrey, J.; Spinapolice, K.; Parke, N.; Mehta, P. M.; Dise, D.; Papich, M.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2009, 32, 5, pp 485-491
AbstractFull Text

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). Previous studies have shown that myelin degradation during MS and EAE resulted in reduced expression of some of the proteins, e.g., the MBP (myelin basic protein), and increased expression of genes such...

Author(s)
Mavaddatiyan, L.; Khezri, S.; Froushani, S. M. A.
Publisher
Urmia University, Faculty of Veterinary Medicine, Urmia, Iran
Citation
Veterinary Research Forum, 2021, 12, 1, pp 47-52
Abstract

This paper discusses the different handling techniques during emergencies and in cases of illnes in various pets such as rabbits, guineapigs, rodents, hamsters, ferrets, ornamental fishes, doves/pigeons, lizards, and reptiles.

Author(s)
Kirsch, K.
Publisher
Schlütersche Verlagsgesellschaft GmbH & Co. KG, Hannover, Germany
Citation
Praktische Tierarzt, 2014, 95, 8, pp 689-693
Abstract

The present study was designed to evaluate the chemotherapeutic efficacy of poly (DL-lactide-co-glycolide) (PLG) nanoparticles (NP) encapsulating three front-line antitubercular drugs (ATDs: rifampicin, RIF; isoniazid, INH and pyrazinamide, PZA) at 2/3rd therapeutic dose. PLG nanoparticles prepared ...

Author(s)
Anjali Sharma; Rajesh Pandey; Sadhna Sharma; Khuller, G. K.
Publisher
Elsevier Science B.V., Amsterdam, Netherlands
Citation
International Journal of Antimicrobial Agents, 2004, 24, 6, pp 599-604
Abstract

We examined the effect of the Ca2+ concentration in the endolymph ([Ca]e) or in the endolymphatic surface cells ([Ca]i) on the endocochlear potential (EP) by using an endolymphatic or perilymphatic perfusion technique, respectively. (i) A large increase in [Ca]e up to ∼10-3 M with a fall in the EP...

Author(s)
Mineharu, A.; Mori, Y.; Nimura, Y.; Takamaki, A.; Araki, M.; Yamaji, J.; Yoshida, R.; Takenaka, H.; Kubota, T.
Publisher
Center for Academic Publications Japan, Tokyo, Japan
Citation
Japanese Journal of Physiology, 2005, 55, 1, pp 53-60

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