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Veterinary information to support practice, based on evidence and continuing education

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Abstract

P-gp (ABCB1) belongs to the group of export transporters that is expressed in various species at biological barriers. Inhibition of P-gp can lead to changes in pharmacokinetics of drugs (drug-drug interactions), which can lead to toxicity and adverse side effects. This study aimed to establish a...

Author(s)
Beusekom, C. D. van; Lange, R.; Schrickx, J. A.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2016, 39, 1, pp 95-97
AbstractFull Text

The possible additive effect of ethanol (EtOH) on verapamil on isolated papillary muscle of cats weighing 1200-1500 g kept in oxygenated Ringer Locke solution was studied. Papillary muscles were dissected from the right ventricle, mounted vertically in an acrylic support and stimulated electrically ...

Author(s)
Martínez, J. L.; Cabrera, H.; Laurido, C.
Publisher
Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan
Citation
Pakistan Veterinary Journal, 2013, 33, 3, pp 382-384
Abstract

Impacts of long-term exposure to sub-lethal verapamil (VRP) at 0.14, 0.28, and 0.57 mg L-1 were examined for 60 days to find the effects on activities of metabolic catalysts as well as molecular reactions in Nile tilapia. Alanine aminotransferase, aspartate aminotransferase, and lactate...

Author(s)
Ajima, M. N. O.; Pandey, P. K.; Kundan Kumar; Nalini Poojary; Gora, A. H.
Publisher
Springer Science + Business Media, London, UK
Citation
Comparative Clinical Pathology, 2020, 29, 1, pp 135-144
Abstract

One of the many properties of propolis, a gift of nature, is that it is a potent antioxidant agent, which has been shown to be a miracle-worker in many different diseases. In this study, its possible protective and reversing effects against hiperoxaluria was investigated in a rat model in...

Author(s)
Narter, F.; Dİren, A.; Kafkaslı, A.; Eronat, A. P.; Seyhan, M. F.; Yılmaz-Aydoğan, H.; Sarıkaya, S.; Hatİpoğlu, S. D.; Sarıca, K.; Ozturk, O.
Publisher
ACG Publications, Gebze-Kocaeli, Turkey
Citation
Records of Natural Products, 2018, 12, 5, pp 445-459
Abstract

The ecotoxicological consequences of residues from pharmaceutical drugs on aquatic biota have necessitated the development of sensitive and reliable techniques to assess the impact of these xenobiotics on aquatic organisms. This study investigated the alteration in DNA structure, molecular...

Author(s)
Ajima, M. N. O.; Pandey, P. K.; Kundan Kumar; Nalini Poojary
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Ecotoxicology and Environmental Safety, 2018, 147, pp 809-816
Abstract

The influx of pharmaceutical drugs and their metabolites have been reported to cause negative impact on aquatic biota. In this study, effects of long-term exposure of verapamil on mutagenic, hematological parameters and activities of the oxidative enzymes of Nile tilapia, Oreochromis niloticus were ...

Author(s)
Ajima, M. N. O.; Pandey, P. K.; Kundan Kumar; Nalini Poojary
Publisher
Taylor & Francis, Abingdon, UK
Citation
Drug and Chemical Toxicology, 2017, 40, 3, pp 286-294
Abstract

The widespread use and availability of calcium channel blockers in human and veterinary medicine pose a risk for inadvertent pet exposure to these medications. Clinical signs of toxicosis can be delayed by many hours after exposure, with lethargy, hypotension, and cardiac rhythm changes as the...

Author(s)
Hayes, C. L.
Publisher
Saunders, An Imprint of Elsevier, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2018, 48, 6, pp 943-957
Abstract

The effect of short chain fatty acids (SCFA) on feline colonic smooth muscle contraction was evaluated in vitro. Colonic tissue was obtained from seven healthy male and female adult cats and seven healthy male and female kittens. Longitudinal and circular colonic smooth muscle strips from proximal...

Author(s)
Rondeau, M. P.; Meltzer, K.; Michel, K. E.; McManus, C. M.; Washabau, R. J.
Publisher
W.B. Saunders, London, UK
Citation
Journal of Feline Medicine and Surgery, 2003, 5, 3, pp 167-173
Abstract

Author(s)
Hayes, C. L.; Knight, M.
Publisher
W.B. Saunders, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2012, 42, 2, pp 263-277
AbstractFull Text

The use and efficacy of different drugs to treat cardiac arrhythmias in cats and dogs are described.

Author(s)
Montaña, A. V.; Bausa, C.; Piedras, M. J. G. M.; Aguirrebeña, A.; Aguilar, B.; Esteve, P.
Publisher
ASIS Veterinaria s.l., Zaragoza, Spain
Citation
Argos - Informativo Veterinario, 2011, No.132, pp 78, 80, 82

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