INTRODUCTION: Methotrexate (MTX) is an important chemotherapeutic and an important anticarcinogen used in cancer patients, but it causes side effects in other tissues. Among these side effects is lung toxicity. Vitamin B12 is a powerful antioxidant and reduces reactive oxygen species. This study...

Cobalamin (cbl) is a water-soluble vitamin found in proteins of animal origin. It is a vital co-factor for DNA and protein synthesis. Consequently, all cells in the body need cbl. Cobalamin deficiency is a prevalent condition in canine and feline chronic enteropathies (CE) and exocrine pancreatic...

Objective: The present study was conducted for the purpose of setting forth the normal serum Hcy, vitamin B₁₂ and folate levels in Van cats of varying ages and genders, and the age-dependent variations of these parameters. Materials and methods: The material of the study consisted of a total of 60...

Methotrexate is used for cure of many cancer types. It has many side effects. For this reason, obtaining a nephroprotective agent is obligatory. In the study, our aim is to determine probable effects of Vitamin B12 on MTX caused kidney damages in rats. Rats were randomly divided into 4 groups,...

Irradiation of food at 50-55 kGy results in a profound, chronic demyelinating-remyelinating disease of the entire central nervous system (CNS) in cats, named Feline Irradiated Diet-Induced Demyelination (FIDID). This study examines the early stages of demyelination and long-term consequences of...

Objective: To determine the effect of aquapuncture at acupuncture point Pericardium 6 (PC-6) on the incidence of dexmedetomidine-induced vomiting and nausea in cats. Study design: Randomized, prospective, crossover study. Animals: A group of 22 cats, 14 females and eight males, aged 1-12 years and...

The present study evaluated recipes of home-prepared diets for dogs and cats published in Portuguese. A total of 106 diets were evaluated: eighty for dogs, twenty-four for cats and two intended for both species. A commercial software package was used to analyse the diets, and an ingredient chemical ...

The chemical composition, recommended dosage, efficacy, safety and risks of Fercobsang (a drug composed of an iron compound, vitamin B12, cobalt and nicotinamide) to treat iron deficiency anaemia in cats and dogs are described.

Exocrine pancreatic insufficiency (EPI) is a condition characterized by a decreased synthesis and secretion of pancreatic enzymes, which results in weight loss, poor hair coat, and diarrhea. The diagnostic test of choice for EPI in domestic cats is feline serum trypsin-like immunoreactivity (fTLI). ...

Serum concentrations of feline pancreatic lipase immunoreactivity (fPLI), feline trypsin-like immunoreactivity (fTLI), and cobalamin are commonly used for the diagnostic investigation of cats with gastrointestinal signs. No information on these parameters in healthy cats less than 1 year of age...