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Abstract

Background: Heart disease is an important cause of morbidity and mortality in cats, but there is limited evidence of the benefit of any medication. Hypothesis: The angiotensin-converting enzyme inhibitor benazepril would delay the time to treatment failure in cats with heart disease of various...

Author(s)
King, J. N.; Martin, M.; Chetboul, V.; Ferasin, L.; French, A. T.; Strehlau, G.; Seewald, W.; Smith, S. G. W.; Swift, S. T.; Roberts, S. L.; Harvey, A. M.; Little, C. J. L.; Caney, S. M. A.; Simpson, K. E.; Sparkes, A. H.; Mardell, E. J.; Bomassi, E.; Muller, C.; Sauvage, J. P.; Diquélou, A.; Schneider, M. A.; Brown, L. J.; Clarke, D. D.; Rousselot, J. F.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2019, 33, 6, pp 2559-2571
Abstract

Background: Combined use of angiotensin-converting enzyme inhibitors and nonsteroidal anti-inflammatory drugs may induce acute kidney injury in humans, especially when combined with diuretics. The objective of this investigation was to evaluate the effects of benazepril, robenacoxib and their...

Author(s)
King, J. N.; Panteri, A.; Graille, M.; Seewald, W.; Friton, G.; Desevaux, C.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2016, 12, 124, pp (23 June 2016)
Abstract

Background: The efficacy and benefits of telmisartan in cats with chronic kidney disease (CKD) have not previously been reported. Hypothesis: Long-term treatment of cats with CKD using telmisartan decreases urine protein-to-creatinine ratio (UP/C) similar to benazepril. Animals: Two-hundred and...

Author(s)
Sent, U.; Gössl, R.; Elliott, J.; Syme, H.; Zimmering, T.
Publisher
Verlag M. & H, Schaper Gmbh, Hannover, Germany
Citation
Kleintierpraxis, 2016, 61, 5, pp 245-257
Abstract

This retrospective study examined cats after initiation of benazepril therapy to determine the frequency of systemic hypotension or elevations in serum creatinine and/or potassium. Medical records review identified azotemic and non-azotemic cats prescribed benazepril. Blood pressure was recorded at ...

Author(s)
Lavallee, J. O.; Norsworthy, G. D.; Huston, C. L.; Chew, D. J.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2017, 53, 2, pp 119-127
Abstract

Background: The efficacy and benefits of telmisartan in cats with chronic kidney disease (CKD) have not previously been reported. Hypothesis: Long-term treatment of cats with CKD using telmisartan decreases urine protein-to-creatinine ratio (UP/C) similar to benazepril. Animals: Two-hundred and...

Author(s)
Sent, U.; Gössl, R.; Elliott, J.; Syme, H. M.; Zimmering, T.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2015, 29, 6, pp 1479-1487
Abstract

OBJECTIVE: To compare the attenuation of the angiotensin I-induced blood pressure response by once-daily oral administration of various doses of angiotensin receptor blockers (irbesartan, telmisartan, and losartan), benazepril hydrochloride, or lactose monohydrate (placebo) for 8 days in clinically ...

Author(s)
Jenkins, T. L.; Coleman, A. E.; Schmiedt, C. W.; Brown, S. A.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2015, 76, 9, pp 807-813
Abstract

The pharmacokinetics and bioavailability of the benazepril and its metabolite benazeprilat, were investigated in cats. A single intravenous (i.v.) or oral (p.o.) administration of benazepril hydrochloride tablets at a dosage of 5 mg was performed in six healthy cats according to a two-period...

Author(s)
Jing-Cheng, Z.; Zhou LianGen; Qu Ying; Qiu ZhenZhen; Cao ChangFu; Zhao HuiMin; Zeng ZhenLing
Publisher
Guoji Shudian (Institute of Scientific and Technological Information of China, China Publications Centre), Beijing, China
Citation
Acta Veterinaria et Zootechnica Sinica, 2014, 45, 12, pp 2050-2056
Abstract

Pimobendan (PIMO) can cause adverse effects, such as mitral valve degeneration, in dogs; however, it is unclear whether these effects occur in cats. Therefore, we aimed to determine whether PIMO or benazepril produces adverse cardiac effects in healthy cats. This was a blinded, randomized,...

Author(s)
Miyagawa, Y.; Machida, N.; Toda, N.; Tominaga, Y.; Takemura, N.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2016, 78, 7, pp 1099-1106
Abstract

The objective of the study was to test the effect of the angiotensin-converting enzyme inhibitor (ACEI) benazepril in cats with chronic kidney disease (CKD). A total of 192 cats with CKD with an initial plasma creatinine concentration ≥2 mg/dL (≥177 µmol/L) and urine specific gravity ≤1.025 were...

Author(s)
King, J. N.; Gunn-Moore, D. A.; Tasker, S.; Gleadhill, A.; Strehlau, G.
Publisher
American College of Veterinary Internal Medicine, Lakewood, USA
Citation
Journal of Veterinary Internal Medicine, 2006, 20, 5, pp 1054-1064
Abstract

Case summary: Systemic arterial hypertension is commonly reported in middle-aged-to-older cats. Amlodipine is recommended as the initial antihypertensive drug in cats. In this case report, gingival hyperplasia secondary to the use of amlodipine in a cat is described. Benazepril as a monotherapy was ...

Author(s)
Desmet, L.; Meer, J. van der
Publisher
Sage Publications Ltd, London, UK
Citation
Journal of Feline Medicine and Surgery Open Reports, 2017, 3, 2, pp 2055116917745236

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