This study aims to characterize clinical features, comorbidities, frequency of bacterial isolation, and survival time in cats with suppurative cholangitis-cholangiohepatitis syndrome (S-CCHS). 168 client-owned cats with S-CCHS were used in this study. Data were prospectively (1980 to 2019)...

Numerous complementary feeds to support liver function are commercially available for small animals. Aiming to furnish a scientific support for clinicians/nutritionists that necessitate a complementary feed to support liver function in dogs and cats, with the present paper, we analyzed scientific...

This article discusses veterinary use of nutraceuticals in cats and dogs. Nutraceuticals are foods (or compounds found in foods) that have functional properties; they are not classed as drugs and are not subject to drug legislation. A brief overview of the market is given. In veterinary medicine it ...

This article describes the use of S-adenosylmethionine (SAMe) in the treatment of liver disorders in cats and dogs, focusing on the pathogenesis of liver disease in cats and dogs, the therapeutic effects of SAMe, its clinical uses and pharmacology.

A large number of aged dogs and cats demonstrate behavioral signs consistent with a clinical diagnosis of cognitive dysfunction syndrome (CDS), which likely is a consequence of pathological brain aging. Identification of treatments that prevent, halt, or reverse CDS, therefore, represents an unmet...

Acute hepatitis has serious implications for both cats and dogs. However many of the clinical symptoms of acute hepatitis vary and are not highly specific, for example dysorexia, lethargy, hepatomegaly, vomiting and polyuria-polydipsia. These symptoms are however more marked with acute hepatitis...

S-adenosylmethionine (SAMe) is reported to have hepatoprotective and antioxidant functions. Acetaminophen (paracetamol) was used to induce oxidative damage in cats, and to then determine the effect of SAMe treatment on erythrocyte morphology, PCV, liver histopathology, thiobarbituate reacting...

Hepatic lipidosis or hepatic steatosis is the most frequent liver disorder in cats. It affects cats of all ages, with the average age of affected cats being seven years. Females appear to be affected more often. Obesity is the main predisposing factor, with other associated factors including...

S-adenosylmethionine (SAMe), an important hepatic metabolite and glutathione (GSH) donor, has been studied mechanistically in vitro, in humans with clinical liver disease, and in experimental animal models of liver disease. Collective findings encourage its therapeutic use in necroinflammatory and...