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Abstract

According to experimental studies with healthy dogs, omeprazole might decrease the CSF production by about 26%; therefore, book texts have been suggested the usage of omeprazole in medical protocols for hydrocephalus treatment. However, to the best knowledge of the authors, the usage and medical...

Author(s)
Pelegrini, L. F.; Silva, N. F.; Campos, O. P. S.; Nery, C. C.; Silva, F. M.; Lemos, R. S.; Yamauchi, K. C. I.; Amude, A. M.
Publisher
Colégio Brasileiro de Patologia Animal, Rio de Janeiro, Brazil
Citation
Pesquisa Veterinária Brasileira, 2019, 39, 10, pp 823-829
Abstract

Clinical signs of syringomyelia and hydrocephalus occur secondary to cerebrospinal fluid (CSF) accumulation within the central nervous system. Omeprazole is recommended to treat these conditions despite little evidence of its capacity to decrease CSF production in the dog. Studies into new...

Author(s)
Girod, M.; Allerton, F.; Vangrinsven, E.; Tutunaru, A. C.; Marchin, J. de; Gómez-Fernández-Blanco, C.; Ruiz-Nuño, A.; Wojnicz, A.; Farnir, F.; Gommeren, K.; Peeters, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 125, pp 266-271
Abstract

Administration of omeprazole by ventriculo-cisternal perfusion or intravenously has been shown to decrease cerebrospinal fluid (CSF) production in dogs and rabbits. Oral omeprazole has consequently been recommended to reduce CSF production in dogs with conditions in which clinical signs may be...

Author(s)
Girod, M.; Allerton, F.; Gommeren, K.; Tutunaru, A. C.; Marchin, J. de; Soens, I. van; Ramery, E.; Peeters, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2016, 209, pp 119-124
Abstract

Objectives: To describe the clinical features of canine gastro-oesophageal reflux disease. Materials and Methods: A search of our medical records produced 20 dogs with clinical signs attributable to oesophageal disease, hyper-regeneratory oesophagopathy and no other oesophageal disorders. The...

Author(s)
Muenster, M.; Hoerauf, A.; Vieth, M.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2017, 58, 5, pp 276-283
Abstract

Omeprazole is used concurrently with clopidogrel to reduce gastrointestinal adverse effects. In humans, the concurrent use of these two drugs can reduce the antiplatelet efficacy of clopidogrel. Our objective was to determine the effects of omeprazole and clopidogrel on platelet function in healthy ...

Author(s)
Thames, B. E.; Lovvorn, J.; Papich, M. G.; Wills, R.; Archer, T.; Mackin, A.; Thomason, J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2017, 40, 2, pp 130-139
Abstract

Background: Serum gastrin concentration can help diagnose gastrinomas in dogs if >3-10× the upper reference limit (URL), but antisecretory therapy and other conditions can also cause hypergastrinemia. Effects of antisecretory therapy (famotidine or ranitidine, omeprazole) on serum gastrin...

Author(s)
Heilmann, R. M.; Berghoff, N.; Grützner, N.; Parnell, N. K.; Suchodolski, J. S.; Steiner, J. M.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 321, pp (7 November 2017)
AbstractFull Text

Primary or secondary hypoparathyroidism is a rare disease in dogs caused by the decreased secretion of parathormone from the parathyroid glands, leading to clinical signs of hypocalcemia. Omeprazole has been increasingly used in veterinary medicine in order to reduce the production of cerebrospinal ...

Author(s)
Aléssio, B. C.; Palumbo, M. I. P.; Souza, A. I.; Andreussi, P. A. T.; Franco, P. A.; Terra, V. J. B.
Publisher
FEPMVZ - Editora, Belo Horizonte, Brazil
Citation
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2019, 71, 4, pp 1137-1142
Abstract

Objective: To identify the relative abundance of commensal pharyngeal flora in healthy dogs and determine if abundance of pharyngeal flora is altered during omeprazole administration. Animals: Eight adult Beagles. Procedures: A total of 3 baseline pharyngeal swabs, collected 48 hours apart, were...

Author(s)
Sullivan, L. A.; Wakayama, J.; Boscan, P. L.; Hyatt, D. R.; Twedt, D. C.; Lappin, M. R.; Dargatz, D. A.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Emergency and Critical Care, 2016, 26, 2, pp 300-304
Abstract

Objectives: To investigate the benefit of supplementing amoxicillin-clavulanic acid therapy with metronidazole in dogs presenting to a primary care veterinary practice with severe haemorrhagic diarrhoea. Materials and methods: Prospective randomised blinded trial on dogs presenting with...

Author(s)
Ortiz, V.; Klein, L.; Channell, S.; Simpson, B.; Wright, B.; Edwards, C.; Gilbert, R.; Day, R.; Caddy, S. L.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2018, 59, 7, pp 398-403
Abstract

Background: The duration of antacid-induced hypergastrinemia after cessation of administration of omeprazole and famotidine apparently has not been determined in dogs. Hypothesis: That serum gastrin will return to basal concentrations by 7 days after cessation of famotidine or omeprazole...

Author(s)
Parente, N. L.; Olivier, N. B.; Refsal, K. R.; Johnson, C. A.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2014, 28, 5, pp 1465-1470

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