Cookies on VetMed Resource

Like most websites we use cookies. This is to ensure that we give you the best experience possible.

 

Continuing to use www.cabi.org  means you agree to our use of cookies. If you would like to, you can learn more about the cookies we use.

VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

Sign up to receive our Veterinary & Animal Sciences e-newsletter, book alerts and offers direct to your inbox.

Results per page:

Search results

Abstract

Introduction: Methotrexate is an antimetabolite used in the treatment of cancer and non-malignant diseases including rheumatoid arthritis, psoriasis and graft vs. host disease. Combination therapy with methotrexate was successful in the treatment of canine lymphoma, mammary tumor and invasive...

Author(s)
Pawlak, A.; Kutkowska, J.; Obmińska-Mrukowicz, B.; Rapak, A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2017, 114, pp 518-523
Abstract

Background: Canine granulomatous mural folliculitis is a very rare cause of scarring alopecia with unknown pathogenesis. Hypothesis/objectives: To report a case of granulomatous mural folliculitis in a dog treated with ciclosporin (Cs) and methotrexate (MTX). Animal: A 13-year-old spayed female...

Author(s)
Panzuti, P.; Mosca, M.; Pin, D.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2020, 31, 2, pp 170-e35
Abstract

Methotrexate may be an alternative to ciclosporin in the treatment of canine atopic dermatitis (cAD) as suggested by recent data. The aim of the study was to investigate both the tolerance and the pharmacokinetic behavior of methotrexate (MTX) in plasma, following intravenous (i.v.), subcutaneous...

Author(s)
Rostang, A.; Mosca, M.; Jeannin, M.; Luissiez, C.; Berny, P.; Fourel, I.; Pin, D.; Prouillac, C.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 5, pp 659-669
Abstract

Canine histiocytic sarcoma (HS) is an aggressive tumor type originating from histiocytic cell lineages. This disease is characterized by poor response to chemotherapy and short survival time. Therefore, it is of critical importance to identify and develop effective antitumor drugs against HS. The...

Author(s)
Asada, H.; Tomiyasu, H.; Goto-Koshino, Y.; Fujino, Y.; Ohno, K.; Tsujimoto, H.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2015, 77, 6, pp 677-684
Abstract

The ability of chemotherapeutic agents to affect the growth of common bacterial pathogens and the relationship between the effects of chemotherapeutics and antimicrobials is largely unknown. The purpose of this study was to describe the susceptibility of canine bacterial isolates to...

Author(s)
Campbell, O.; Gagnon, J.; Rubin, J. E.
Publisher
Wiley, Oxford, UK
Citation
Letters in Applied Microbiology, 2019, 69, 5, pp 353-357
Abstract

The objective of the study was to retrospectively evaluate the short-term safety of intrathecal administration of cytosine arabinoside alone or in combination with methotrexate in dogs and cats. One hundred and twelve dogs and eight cats admitted between September 2008 and December 2013, diagnosed...

Author(s)
Genoni, S.; Palus, V.; Eminaga, S.; Cherubini, G. B.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2016, 14, 3, pp 331-336
Abstract

Objective: To describe the successful use of charcoal hemoperfusion (HP) and hemodialysis (HD) in a dog in the treatment of methotrexate (MTX) toxicosis. Case Summary An American Pit Bull Terrier accidentally ingested 56.8 mg/m2 of MTX. The patient's initial serum MTX concentration was 0.11 µmol/L. ...

Author(s)
Pardo, M.; Lanaux, T.; Davy, R.; Bandt, C.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Emergency and Critical Care, 2018, 28, 3, pp 269-273
Abstract

A five-year-old female entire cocker spaniel was admitted for acute obtundation and non-ambulatory tetraparesis. MRI of the brain revealed a mass lesion in the right olfactory and frontal lobe area and in the right frontal sinus. Transfrontal craniotomy was performed for surgical excision, with...

Author(s)
Lopez, P. P.; Rasotto, R.; Caine, A.; Cherubini, G. B.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2018, 6, 2, pp e000570
AbstractFull Text

In humans, large granular lymphocytic leukaemia (LGLL) is a low-grade, indolent lymphoproliferative disorder of large granular lymphocytes (LGL) associated with autoimmune disorders; including rheumatoid arthritis and single or multiple cytopenias; particularly neutropenia. Therapy largely centres...

Author(s)
Elliott, J.; Villiers, E.
Publisher
Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
Citation
Open Veterinary Journal, 2018, 8, 2, pp 118-124
Abstract

Case Description - 2 English Pointers were suspected of having consumed toxic doses of methotrexate, a dihydrofolate reductase inhibitor frequently used in human and veterinary chemotherapeutic protocols. Clinical Findings - Potentially toxic plasma concentrations of methotrexate were detected in...

Author(s)
Lewis, D. H.; Barfield, D. M.; Humm, K. R.; Goggs, R. A.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2010, 237, 12, pp 1450-1454

Refine Results

Sort Order
Author
Geographical Location
Item Type
Language
Organisms
Subject Topics