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Abstract

Previously, antioxidants have not been evaluated for treatment of parvoviral diarrhea in dogs. In this study, antioxidant potential of N-acetylcysteine (NAC) in dogs infected with canine parvovirus with a nonblinded randomized clinical trial has been carried out. A total 18 parvo-infected dogs were ...

Author(s)
Gaykwad, C.; Garkhal, J.; Chethan, G. E.; Nandi, S.; De, U. K.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, 1, pp 68-75
Abstract

OBJECTIVE: To evaluate the in vitro effect of 20% N-acetylcysteine (NAC) on the viscosity of normal canine bile. ANIMALS: Bile samples obtained from 10 adult dogs euthanized for reasons unrelated to biliary disease. PROCEDURES: Each sample was centrifuged to remove particulates, then divided into 3 ...

Author(s)
Boullhesen-Williams, T.; Townsend, K. L.; Milovancev, M.; White, N. C.; Harris, C. G.; Adiga, P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2019, 80, 1, pp 74-78
Abstract

Background: Approved treatments for canine otitis externa are limited in variety and may contain ototoxic ingredients. With bacterial resistance an ongoing concern, it would be ideal if non-ototoxic agents combined with antibiotics resulted in a synergistic effect, requiring lower antibiotic...

Author(s)
May, E. R.; Ratliff, B. E.; Bemis, D. A.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2019, 30, 6, pp 531-e161
Abstract

Otitis externa (OE) is a frequently reported disorder in dogs associated with secondary infections by Staphylococcus, Pseudomonas and yeast pathogens. The presence of biofilms may play an important role in the resistance of otic pathogens to antimicrobial agents. Biofilm production of twenty ...

Author(s)
Chan WeiYee; Hickey, E. E.; Page, S. W.; Trott, D. J.; Hill, P. B.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2019, 42, 6, pp 682-692
Abstract

Background: An antibiotic adjuvant is a chemical substance used to modify or augment the effectiveness of primary antimicrobial agents against drug-resistant micro-organisms. Its use provides an alternative approach to address the global issue of antimicrobial resistance and enhance antimicrobial...

Author(s)
Chan WeiYee; Khazandi, M.; Hickey, E. E.; Page, S. W.; Trott, D. J.; Hill, P. B.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2019, 30, 2, pp 133-e38
Abstract

Objectives: To assess whether combination antioxidant supplementation for 30 days in systemically ill dogs alters antioxidant status, degree of lipid peroxidation, clinical score and survival. Materials and Methods: Forty client-owned systemically-ill hospitalised dogs were eligible for inclusion. ...

Author(s)
Hagen, D. M.; Ekena, J. L.; Geesaman, B. M.; Viviano, K. R.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2019, 60, 9, pp 543-550
Abstract

Background: N-Acetylcysteine (NAC) has the potential to be a useful therapeutic agent for the treatment of otitis externa due to its antimicrobial and mucolytic properties, as well as its ability to disrupt bacterial biofilm. Hypothesis/Objectives: To determine the antibacterial activity of NAC...

Author(s)
May, E. R.; Conklin, K. A.; Bemis, D. A.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2016, 27, 3, pp e47
Abstract

Endotracheal intubation is a common procedure, rarely associated with life-threatening complications (e.g., tracheal rupture, necrosis, foreign body). A 1.5-year-old English Bulldog was presented for respiratory distress, with increased respiratory efforts and stridor, 2 days after endotracheal...

Author(s)
Robin, E.; Guieu, L. V.; Boedec, K. le
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 2, pp 550-555
Abstract

Objective: To describe the treatment and clinical course of a dog accidentally prescribed 10 times the recommended dose of colchicine (0.3 mg/kg/d instead of 0.03 mg/kg/d). Case Summary: After glaucoma surgery, a 1-year-old male neutered Pomeranian weighing 6.8 kg was prescribed 1,000 µg colchicine ...

Author(s)
Goodman, I. H.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Emergency and Critical Care, 2020, 30, 1, pp 74-80
Abstract

An 8-year-old, spayed female Chihuahua mixed breed dog was presented for dyspnea and was subsequently mechanically ventilated. Propofol was utilized as part of the anesthetic protocol. The dog developed rhabdomyolysis, myoglobinuria, cardiac arrhythmias, liver enzyme elevation, and...

Author(s)
Mallard, J. M.; Rieser, T. M.; Peterson, N. W.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2018, 59, 11, pp 1216-1222

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