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Abstract

The UK Government recognised the importance of vaccines in the control of new emerging disease threats and in 2015 established the UK Vaccine Network to focus on specific areas of need. One of these was the understanding of what is involved in the development of a new vaccine and what are the...

Author(s)
Francis, M. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2020, 38, 29, pp 4512-4515
Abstract

Gram-negative bacteria is the main causative agents for columnaris disease outbreak to finfishes. The outer membrane proteins (OMPs) candidate of Flavobacterium columnare bacterial cell served a critical component for cellular invasion targeted to the eukaryotic cell and survival inside the...

Author(s)
Manojit Bhattacharya; Malick, R. C.; Niladri Mondal; Prasanta Patra; Pal, B. B.; Patra, B. C.; Das, B. K.
Publisher
Taylor & Francis, Abingdon, UK
Citation
Journal of Biomolecular Structure and Dynamics, 2020, 38, 2, pp 450-459
Abstract

COVID-19 has become one of the biggest health concern, along with huge economic burden. With no clear remedies to treat the disease, doctors are repurposing drugs like chloroquine and remdesivir to treat COVID-19 patients. In parallel, research institutes in collaboration with biotech companies...

Author(s)
Bijayeeta Deb; Hemal Shah; Suchi Goel
Publisher
Indian Academy of Sciences, Bengaluru, India
Citation
Journal of Biosciences, 2020, 45, 82, pp (12 June 2020)
Abstract

Studies of DNA vaccines have shown that understanding the mechanism of DNA vaccine-mediated action is the key for vaccine development. Current knowledge has shown the presence of antigen presenting cells (APCs) involving in B and T cells at the muscle injection site and the upregulation of type I...

Author(s)
Chang ChiaJung
Publisher
Elsevier Ltd, Oxford, UK
Citation
Fish & Shellfish Immunology, 2020, 101, pp 252-260
Abstract

The emergence of the strain of coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and its impact on global health have made imperative the development of effective and safe vaccines for this lethal strain. SARS-CoV-2 now adds to the list of coronavirus diseases that have...

Author(s)
Padron-Regalado, E.
Publisher
Springer Healthcare, London, UK
Citation
Infectious Diseases and Therapy, 2020, 9, 2, pp 255-274
Abstract

A major obstacle to developing vaccines against cryptosporidiosis, a serious diarrheal disease of children in developing countries, is the lack of rodent models essential to identify and screen protective immunogens. Rodent models commonly used for drug discovery are unsuitable for vaccine...

Author(s)
Dayao, D. A.; Sheoran, A.; Carvalho, A.; Xu HongBin; Beamer, G.; Widmer, G.; Tzipori, S.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2020, 50, 1, pp 19-22
Abstract

Inactivated vaccines are often applied with adjuvants in commercial fish farming. Although some mineral or non-mineral oil adjuvants show efficient improvement with inactivated vaccines, but sometimes bring side effects such as tissue adhesion and granulomatous lesion at the injection site. CpG ODN ...

Author(s)
Sun Xiang; Jin Peng; Liu Qin; Wang QiYao; Zhang YuanXing; Liu XiaoHong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Fish & Shellfish Immunology, 2020, 98, pp 312-317
Abstract

The drivers of vaccine development are many and varied. They include, for example, recognition of the burden of a vaccine-targeted disease, prioritisation of the multiple problems associated with a disease, consideration of the differing socio-economic situations under which vaccines are used, the...

Author(s)
Thomas, L. F.; Bellet, C.; Rushton, J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2019, 37, 30, pp 3974-3980
AbstractFull Text

Vaccination is a common routine for prevention and control of human and animal diseases by inducing antibody responses and cell-mediated immunity in the body. Through vaccinations, smallpox and some other diseases have been eradicated in the past few years. The use of a pathogen itself or a subunit ...

Author(s)
Wang, Y. B.; Wang, L. P.; Li, P.
Publisher
Polish Academy of Sciences, Committee of Veterinary Sciences, Olsztyn-Kortowo II, Poland
Citation
Polish Journal of Veterinary Sciences, 2018, 21, 3, pp 643-649
Abstract

Background: Although rigorous efforts have substantially decreased the malaria burden through decades, it still threatens the lives of millions of children. Development of an effective vaccine can provide important approach in malaria control strategies. Unfortunately, development of an effective...

Author(s)
Mahmoudi, S.; Keshavarz, H.
Publisher
Tehran University of Medical Sciences, Centre for Electronic Resources Provision and Journal Improvement, Tehran, Iran
Citation
Iranian Journal of Parasitology, 2018, 13, 1, pp 1-10

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