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Abstract

Background: Genome editing technologies provide new tools for genetic improvement and have the potential to become the next game changer in animal and plant breeding. The aim of this study was to investigate how genome editing in combination with genomic selection can accelerate the introduction of ...

Author(s)
Bastiaansen, J. W. M.; Bovenhuis, H.; Groenen, M. A. M.; Megens, H. J.; Mulder, H. A.
Publisher
BioMed Central Ltd, London, UK
Citation
Genetics, Selection, Evolution, 2018, 50, 18, pp (16 April 2018)
AbstractFull Text

Genome editing is the process of making precise, targeted sequence changes in the deoxyribonucleic acid of living cells and organisms. Recent advances have made genome editing widely applicable, offering the opportunity to rapidly advance basic and applied biology. In the face of the mounting food, ...

Publisher
Council for Agricultural Science and Technology (CAST), Ames, USA
Citation
Issue Paper - Council for Agricultural Science and Technology, 2018, No.60, pp 24 pp.
Abstract

Traditionally, genetic engineering in the pig was a challenging task. Genetic engineering of somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically engineered (GE) pigs carrying site-specific modifications. However, due to difficulties in engineering the genome of...

Author(s)
Lee KiHo; Farrell, K.; Uh KyungJun
Publisher
CSIRO, Collingwood, Australia
Citation
Reproduction, Fertility and Development, 2020, 32, 1/2, pp 40-49
Abstract

Historically, genetic engineering in livestock proved to be challenging. Without stable embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed to produce many of the genetically engineered (GE) livestock models. Through the genetic engineering of somatic cells ...

Author(s)
Lee KiHo; Uh KyungJun; Farrell, K.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2020, 150, pp 229-235
Abstract

Advances in genome-editing technologies and sequencing of animal genomes enable researchers to generate genome-edited (GE) livestock as valuable animal models that benefit biological researches and biomedical and agricultural industries. As birds are an important species in biology and agriculture, ...

Author(s)
Lee Joonbum; Kim DongHwan; Lee Kichoon
Publisher
MDPI AG, Basel, Switzerland
Citation
International Journal of Molecular Sciences, 2020, 21, 11,
Abstract

Genome editing, particularly using of site-directed nucleases such as the CRISPR system, has spread rapidly through the biological sciences. Genome editing in crops could significantly speed up the progress of breeding programs. It could drive the development of traits in new crops and allow...

Author(s)
Ricroch, A.
Publisher
Springer, Dordrecht, Netherlands
Citation
Transgenic Research, 2019, 28, Suppl. 2, pp 45-52
Abstract

Milk and meat from cattle and buffaloes contribute 45% of the global animal protein supply, followed by chickens (31%), and pigs (20%). In 2016, the global cattle population of 1.0 billion head produced 6.5 billion tons of cows' milk, and 66 million tons of beef. In the past century, cattle...

Author(s)
Eenennaam, A. L. van
Publisher
Springer, Dordrecht, Netherlands
Citation
Transgenic Research, 2019, 28, Suppl. 2, pp 93-100
Abstract

There have been revolutionary progresses in genome engineering in the past few years. The newly-emerged genome editing technologies including zinc-finger nuclease (ZFN), transcription activator-like effector nuclease (TALEN) and clustered regularly interspaced short palindromic repeats associated...

Author(s)
Zhu Bo; Ge Wei
Publisher
Elsevier, Amsterdam, Netherlands
Citation
General and Comparative Endocrinology, 2018, 257, pp 3-12
Abstract

Recently, successful one-step genome editing by microinjection of CRISPR/Cas9-related mRNA components into the porcine zygote has been described. Given the relatively long gestational period and the high cost of housing swine, the establishment of an effective microinjection-based porcine genome...

Author(s)
Sato, M.; Kosuke, M.; Koriyama, M.; Inada, E.; Saitoh, I.; Ohtsuka, M.; Nakamura, S.; Sakurai, T.; Watanabe, S.; Miyoshi, K.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2018, 108, pp 29-38
Abstract

Transgenesis and genome editing in birds are based on a unique germline transmission system using primordial germ cells (PGCs), which is quite different from the mammalian transgenic and genome editing system. PGCs are progenitor cells of gametes that can deliver genetic information to the next...

Author(s)
Han JaeYong; Park YoungHyun
Publisher
BioMed Central Ltd, London, UK
Citation
Journal of Animal Science and Biotechnology, 2018, 9, 19, pp (31 January 2018)

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