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AbstractFull Text

Objective: To provide a reference for strengthening the supervision and prevention and control of this disease, the prevalence of porcine reproductive and respiratory syndrome in Guigang, Guangxi was studied. Method: Through the analysis of Nsp2 gene, new specific diagnostic primers were...

Author(s)
Zhang ShuXiang; He QiSong; Kong ZiRong; Guo JianGang; Zhou QingAn; Huang ShengBin; Han YinHua; Xiong Yi
Publisher
Editorial Department of Southwest China Journal of Agricultural Sciences, Chengdu, China
Citation
Southwest China Journal of Agricultural Sciences, 2019, 32, 1, pp 208-213
Abstract

Cyclin-dependent kinase 9 (CDK9) is a key regulator of RNA-polymerase II and a candidate therapeutic target for various virus infections such as respiratory syncytial virus, herpes simplex virus, human adenovirus, human cytomegalovirus, hepatitis virus B, and human papillomavirus. We employed...

Author(s)
Wang MengDi; Yang Le; Meng JieJie; Pan JiaJia; Zhang Chao; Wan Bo; Sun Yu; Wang Jiang; Chu BeiBei; Zhang GaiPing
Publisher
Elsevier Ltd, Oxford, UK
Citation
Molecular Immunology, 2021, 135, pp 351-364
Abstract

The ubiquitin-proteasome system (UPS) plays a vital role in cellular protein homeostasis by ensuring protein quality control and maintaining a critical level of important regulatory proteins. Thus, it is not surprising that the functional UPS is manipulated by viruses to assist in viral...

Author(s)
Pang Yu; Li Mao; Zhou YanRong; Liu Wei; Tao Ran; Zhang HeJin; Xiao ShaoBo; Fang LiuRong
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2021, 253,
Abstract

The MARC-145 cell line is commonly used to isolate porcine reproductive and respiratory syndrome virus (PRRSV) for diagnostics, research, and vaccine production, but it yields frustratingly low success rates of virus isolation (VI). The ZMAC cell line, derived from porcine alveolar macrophages, has ...

Author(s)
Wannarat YimIm; Huang HaiYan; Park Jie; Wang Chong; Calzada, G.; Gauger, P.; Harmon, K.; Main, R.; Zhang JianQiang
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Journal of Clinical Microbiology, 2021, 59, 3,
Abstract

The aim of this study was to reproduce severe pneumonic lesions, similar to those during naturally-occurring porcine respiratory disease complex, in pigs dually inoculated with porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae at 6 weeks of age, followed by...

Author(s)
Lee JooYoung; Park KeeHwan; Oh Taehwan; Yang Siyeon; Suh Jeongmin; Ham HeeJin; Chae Chanhee
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2021, 83, 3, pp 427-430
Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) mainly infects monocyte/macrophage lineage and regulates the production of cytokines to influence host immune responses. Interleukin-6 (IL-6) is originally identified as a B-cell stimulatory factor and has important functions in regulating ...

Author(s)
Xu YangYang; Wang HongLei; Zhang Xuan; Zheng XiaoJie; Zhu YingQi; Han HaiGe; Feng WenHai
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2021, 256,
Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important swine viruses globally, including in Ontario, Canada. Understanding the evolution and relation of the various PRRSV genotypes in Ontario can provide insight into the epidemiology of the virus. The objectives of ...

Author(s)
Melmer, D. J.; Friendship, R.; O'Sullivan, T. L.; Greer, A. L.; Novosel, D.; Ojkić, D.; Poljak, Z.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2021, 85, 2, pp 83-92
Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) displays restricted tropism to porcine alveolar macrophages in nature. Meanwhile, non-porcine cell lines derived from African green monkey kidney cell lines are permissive to PRRSV, resulting in their widespread use in PRRSV research....

Author(s)
Morozumi, T.; Takenouchi, T.; Wada, E.; Uenishi, H.; Nishiyama, Y.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Journal of Virological Methods, 2021, 288,
Abstract

Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically devastating viral diseases in the global pig industry. Recently, we isolated and plaque-purified porcine reproductive and respiratory syndrome virus (PRRSV) strain SC2020-1 from "aborted piglets" on a farm in...

Author(s)
Zhao Jun; Zhu Ling; Deng HuiDan; Li FengQing; Xu Lei; Sun XiangAng; Yin WenQi; Kuang ShengYao; Li ShuWei; Zhou YuanCheng; Xu ZhiWen
Publisher
Springer-Wien, Vienna, Austria
Citation
Archives of Virology, 2021, 166, 6, pp 1769-1773
Abstract

Porcine Reproductive and Respiratory Syndrome (PRRS) is a devastating disease among the most notorious threats to the swine industry worldwide and is characterized by respiratory distress and reproductive failure. Highly evolving porcine reproductive and respiratory syndrome virus (PRRSV) strains...

Author(s)
Yang Chao; Zuo QingWei; Liu Xiao; Zhao Qian; Pu HaoYu; Gao LiBo; Zhao LianFeng; Guo ZhiGang; Lin YingBo; Liu JianPing; Bi JunLong; Yin GeFen
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2021, 255,

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