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AbstractFull Text

Objective: Using the characteristics of MS2 phage coat protein to self-assemble and encapsulate exogenous nucleic acid in vitro, a quality control product for detecting Porcine Epidemic Diarrhea Virus was prepared by RT-PCR, and its stability and resistance to RNase degradation were studied....

Author(s)
Wang GuoQiang; Ma HongFang; Zeng RuaHui; Jia Yuan; Su YunFang; Mao MengDi; Liu BaoGuang; Shang LiZhi; Zhang ZhenQiang
Publisher
Editorial Department of Southwest China Journal of Agricultural Sciences, Chengdu, China
Citation
Southwest China Journal of Agricultural Sciences, 2020, 33, 11, pp 2686-2692
Abstract

Swine enteric diseases have caused significant economic loss and have been considered as the major threat to the global swine industry. Several coronaviruses, including transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV), have been identified as the causative...

Author(s)
Luo Lei; Wang ShaoHua; Zhu Lin; Fan BaoChao; Liu Tong; Wang LeFeng; Zhao PanPan; Dang YanNa; Sun Pei; Chen JianWen; Zhang YunHai; Chang XinJian; Yu ZhengYu; Wang HuaNan; Guo RongLi; Li Bin; Zhang Kun
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2019, 9, 1, pp 13186
Abstract

Coronavirus (CoV) nonstructural protein 1 (nsp1) inhibits cellular gene expression and antagonizes interferon (IFN) response. Porcine epidemic diarrhea virus (PEDV) infects pigs and causes high mortality in neonatal piglets. We hypothesized that a recombinant PEDV carrying mutations at the...

Author(s)
Niu XiaoYu; Kong FanZhi; Xu JiaYu; Liu MingDe; Wang QiuHong
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Journal of Virology, 2022, 96, 11,
Abstract

Coronaviral papain-like proteases (PLpros) are essential enzymes that mediate not only the proteolytic processes of viral polyproteins during virus replication but also the deubiquitination and deISGylation of cellular proteins that attenuate host innate immune responses. Therefore, PLpros are...

Author(s)
Chu HsuFeng; Cheng ShuChun; Sun ChiaoYin; Chou ChiYuan; Lin TaHsien; Chen WeiYi
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Journal of Virology, 2022, 96, 1,
Abstract

In this study, we investigated the correlation between the mechanism involved in porcine epidemic diarrhea virus (PEDV) replication and autophagic flux. In this study, we found that as PEDV replicated, production of LC3-II was significantly induced up to 24 h post-infection (hpi). Interestingly,...

Author(s)
Park JaeYeon; Ryu Jihoon; Hong EuiJu; Shin HyunJin
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2022, 14, 5,
Abstract

Porcine epidemic diarrhea is a devastating porcine disease that is caused by the alphacoronavirus porcine epidemic diarrhea virus (PEDV). Like other members of the Coronaviridae family, PEDV encodes a multifunctional papain-like protease 2 (PLP2) that has the ability to process the coronavirus...

Author(s)
Durie, I. A.; Dzimianski, J. V.; Daczkowski, C. M.; McGuire, J.; Faaberg, K.; Pegan, S. D.
Publisher
Wiley, Copenhagen, Denmark
Citation
Acta Crystallographica Section D, Structural Biology, 2021, 77, 7, pp 943-953
Abstract

Porcine epidemic diarrhea virus (PEDV) is a globally distributed alphacoronavirus that can cause porcine epidemic diarrhea(PED). The emergence of mutant strains since2010 has caused piglet mortality rates as high as100%, causing huge economic losses to the pig industry.As an obligate intracellular...

Author(s)
Li MingWei; Wu Yang
Publisher
Chinese Journal of Preventive Veterinary Medicine, Harbin, China
Citation
Zhongguo Yufang Shouyi Xuebao / Chinese Journal of Preventive Veterinary Medicine, 2021, 43, 10, pp 1131-1131
Abstract

Background: On October 30, 2020, piglets and sows in the farrowing house of a pig farm in Jiangxi showed clinical symptoms such as anorexia, watery diarrhea, and vomiting. Epidemiological test, clinical necropsy, and RT-PCR test were carried out on the pig farm for diagnosis. After comprehensive...

Author(s)
Gao Qi; Zheng ZeZhong; Wang Heng; Yi SongQiang; Zhang GuiHong; Gong Lang
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2021, 7, July,
Abstract

Porcine epidemic diarrhea (PED) is an acute, highly contagious intestinal swine disease caused by porcine epidemic diarrhea virus (PEDV). In addition to known PEDV infection targets (villous small intestinal epithelial cells), recent reports suggest that dendritic cells (DCs) may also be targeted...

Author(s)
Wang Jie; Wang YaJing; Liu Bing; He YunWei; Li ZhiWei; Zhao Qin; Nan YuChen; Wu ChunYan
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Immunology, 2021, 12, November,
Abstract

Porcine epidemic diarrhea (PED) caused by porcine epidemic diarrhea virus (PEDV) is widespread in the world. In recent years, the increased virulence of the virus due to viral variations, has caused great economic losses to the pig industry in many countries. It is always worthy to find effective...

Author(s)
Xie YuanChao; Guo XiaoZhen; Hu TianWen; Wei DaiBao; Ma XiuLi; Wu JiaQiang; Huang Bing; Shen JingShan
Publisher
Springer Singapore, Singapore, Singapore
Citation
Virologica Sinica, 2021, 36, 5, pp 997-1005

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