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Abstract

Background: Hematophagous Culicoides spp. biting midges are of great agricultural importance as livestock, equine, and wildlife pests and as vectors of the orbiviruses bluetongue, epizootic hemorrhagic disease and African horse sickness. To obtain a blood meal, midges deposit saliva containing...

Author(s)
Lehiy, C. J.; Reister-Hendricks, L. M.; Ruder, M. G.; McVey, D. S.; Drolet, B. S.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 358, pp (20 June 2018)
Abstract

Background: Bluetongue virus (BTV) causes non-contagious haemorrhagic disease in ruminants and is transmitted by Culicoides spp. biting midges. BTV encodes four non-structural proteins of which NS3/NS3a is functional in virus release. NS3/NS3a is not essential for in vitro virus replication....

Author(s)
Feenstra, F.; Drolet, B. S.; Boonstra, J.; Rijn, P. A. van
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2015, 8, 476, pp (17 September 2015)
Abstract

Culicoides sonorensis biting midges are confirmed vectors of epizootic hemorrhagic disease virus (EHDV), which causes mortality in white-tailed deer and ruminant populations. Currently, of the seven EHDV serotypes, only 1, 2, and 6 are detected in the USA, and very few studies have focused on the...

Author(s)
Mills, M. K.; Ruder, M. G.; Nayduch, D.; Michel, K.; Drolet, B. S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 11, pp e0188865
Abstract

Replication of arboviruses, including orbiviruses, within the vector has been shown to be temperature dependent. Cooler ambient temperatures slow virus replication in arthropod vectors, whereas viruses replicate faster and to higher titers at warmer ambient temperatures. Previous research with...

Author(s)
Ruder, M. G.; Stallknecht, D. E.; Howerth, E. W.; Carter, D. L.; Pfannenstiel, R. S.; Allison, A. B.; Mead, D. G.
Publisher
Entomological Society of America, Annapolis, USA
Citation
Journal of Medical Entomology, 2015, 52, 5, pp 1050-1059
Abstract

Two cell lines, ABADRL-Cs-W3 (W3) and ABADRL-Cs-W8A (W8), were developed from a field population of Culicoides sonorensis. The cell lines were characterized by isozyme phenotyping and the ability to support the replication of bluetongue virus (BLU) and epizootic haemorrhagic disease virus (EHDV)...

Author(s)
McHolland, L. E.; Mecham, J. O.
Publisher
Entomological Society of America, Lanham, USA
Citation
Journal of Medical Entomology, 2003, 40, 3, pp 348-351
Abstract

Defining predictors for insect-transmitted virus (arbovirus) disease cycles requires an understanding of the molecular interactions between the virus and vector insect. Studies of orbiviruses from numerous geographic regions have indicated that virus genes are affected by insect population...

Author(s)
Campbell, C. L.; McNulty, M. J.; Letchworth, G. J.; Wilson, W. C.
Publisher
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy
Citation
Veterinaria Italiana, 2004, 40, 3, pp 390-395
Abstract

Bluetongue virus (BTV) infects sheep, cattle and other ruminants and is transmitted by Culicoides spp. of biting midges. Virus is typically isolated and characterized by infection of susceptible vertebrate cells that undergo detectable and measurable cytopathic effects. Cell lines derived from C....

Author(s)
Mecham, J. O.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Journal of Virological Methods, 2006, 135, 2, pp 269-271

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