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Abstract

Background: Bluetongue virus (BTV) causes non-contagious haemorrhagic disease in ruminants and is transmitted by Culicoides spp. biting midges. BTV encodes four non-structural proteins of which NS3/NS3a is functional in virus release. NS3/NS3a is not essential for in vitro virus replication....

Author(s)
Feenstra, F.; Drolet, B. S.; Boonstra, J.; Rijn, P. A. van
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2015, 8, 476, pp (17 September 2015)
AbstractFull Text

The severity of Bluetongue clinical disease in ruminants varies greatly depending on the outbreak serotype/strain, animal species/breed, and immune status of the herd. To predict disease risk from any of the 26 Bluetongue virus (BTV) serotypes identified to date, experimental animal susceptibility...

Author(s)
Drolet, B. S.; Reister, L. M.; Lehiy, C. J.; Rijn, P. A. van; Bowen, R. A.
Publisher
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy
Citation
Veterinaria Italiana, 2015, 51, 4, pp 379-384
Abstract

Background: Hematophagous Culicoides spp. biting midges are of great agricultural importance as livestock, equine, and wildlife pests and as vectors of the orbiviruses bluetongue, epizootic hemorrhagic disease and African horse sickness. To obtain a blood meal, midges deposit saliva containing...

Author(s)
Lehiy, C. J.; Reister-Hendricks, L. M.; Ruder, M. G.; McVey, D. S.; Drolet, B. S.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 358, pp (20 June 2018)
Abstract

Culicoides biting midges (Diptera: Ceratopogonidae) are hematophagous insects with over 1400 species distributed throughout the world. Many of these species are of particular agricultural importance as primary vectors of bluetongue and Schmallenberg viruses, yet little is known about Culicoides...

Author(s)
Lehiy, C. J.; Drolet, B. S.
Publisher
PeerJ, San Francisco, USA
Citation
PeerJ, 2014, 2, 426, pp e426
Abstract

Culicoides sonorensis biting midges are confirmed vectors of epizootic hemorrhagic disease virus (EHDV), which causes mortality in white-tailed deer and ruminant populations. Currently, of the seven EHDV serotypes, only 1, 2, and 6 are detected in the USA, and very few studies have focused on the...

Author(s)
Mills, M. K.; Ruder, M. G.; Nayduch, D.; Michel, K.; Drolet, B. S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 11, pp e0188865
Abstract

Vesicular stomatitis virus (VSV) is an important vector-borne pathogen of bovine and equine species, causing a reportable vesicular disease. The matrix (M) protein of VSV is multifunctional and plays a key role in cytopathogenesis, apoptosis, host protein shut-off, and virion assembly/budding. Our...

Author(s)
Irie, T.; Liu, Y. L.; Drolet, B. S.; Carnero, E.; García-Sastre, A.; Harty, R. N.
Publisher
MDPI Publishing, Basel, Switzerland
Citation
Viruses, 2012, 4, 9, pp 1605-1618
Abstract

Background: Culicoides sonorensis (Diptera: Ceratopogonidae) is a vector of epizootic hemorrhagic disease virus (EHDV) serotypes 1 and 2 in North America, where these viruses are well-known pathogens of white-tailed deer (WTD) and other wild ruminants. Although historically rare, reports of...

Author(s)
Ruder, M. G.; Howerth, E. W.; Stallknecht, D. E.; Allison, A. B.; Carter, D. L.; Drolet, B. S.; Klement, E.; Mead, D. G.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2012, 5, 236, pp (17 October 2012)
Abstract

To determine whether vesicular stomatitis virus (VSV) infection of Culicoides sonorensis Wirth & Jones (Diptera: Ceratopogonidae) affects subsequent blood-feeding behavior, midges injected with either virus-infected or virus-free cell lysates were allowed to blood feed for short (10-min) or long...

Author(s)
Bennett, K. E.; Hopper, J. E.; Stuart, M. A.; West, M.; Drolet, B. S.
Publisher
Entomological Society of America, Lanham, USA
Citation
Journal of Medical Entomology, 2008, 45, 5, pp 921-926
Abstract

Salivary proteins of Culicoides biting midges are thought to play a key role in summer eczema (SE), a seasonal recurrent allergic dermatitis in horses. The present study describes the identification, expression and clinical relevance of a candidate allergen of the North American midge Culicoides...

Author(s)
Langner, K. F. A.; Jarvis, D. L.; Nimtz, M.; Heselhaus, J. E.; McHolland, L. E.; Leibold, W.; Drolet, B. S.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2009, 39, 2, pp 243-250
Abstract

To determine the vector competence of C. sonorensis midges for vesicular stomatitis virus (VSV)-New Jersey, insects were experimentally infected per os and sampled over time. Viral replication, as determined by in situ hybridization, was seen in epithelial, neural and haemolymph cell types...

Author(s)
Drolet, B. S.; Campbell, C. L.; Stuart, M. A.; Wilson, W. C.
Publisher
Entomological Society of America, Lanham, USA
Citation
Journal of Medical Entomology, 2005, 42, 3, pp 409-418

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