One Health
Research Roadmap 2025–2030
Three big questions
Where are we now?
One Health research has evolved, revealing global disparities and funding
insights that inform alignment with – and development of – international
action plans.
What has been researched so far?
The amount of research labelled ‘One Health’ has increased both in volume and diversity, and topics are increasingly examined across disciplines reflecting the broadened scope of One Health.
Read moreWho has implemented this research?
One Health research collaborations in the past decade have revealed notable power imbalances between the Global North and Global South.
Read moreWho has funded One Health research?
An examination of the funders behind One Health research provides recommendations for funders to maximize the impact of their investment for better health outcomes for all.
Coming up
Where are the research gaps?
Identifying research gaps ensures policies and decisions address overlooked topics and regions, guiding targeted, inclusive, and impactful One Health interventions.
Which research topics remain under explored?
The amount of research labelled ‘One Health’ has increased both in volume and diversity, and topics are increasingly examined across disciplines reflecting the broadened scope of One Health.
Which regions/countries are underserved?
Despite rising contributions from lower- and middle-income countries, One Health research remains dominated by high-income countries, limiting local influence and regional relevance.
Spotlight on zoonosis: where do we lack evidence and systematic data?
A review evaluates existing evidence for agrifood-related drivers of zoonotic diseases and underscores the need for integrated One Health research to inform targeted interventions.
Where do we go next?
Strategic insights into future One Health research priorities are vital for guiding impactful funding, addressing evidence gaps, and fostering integrated, cross-sectoral global health solutions.
What priorities should shape future OH research?
A global horizon-scanning exercise has identified emerging One Health research priorities, guiding decision-makers toward evidence-driven investments and cross-sectoral collaboration.
How should funders support research for greatest impact?
Expert views on the key challenges in One Health funding, providing strategic guidance to develop practical solutions.
Coming up
How to better integrate plant health into One Health?
Plant health is an essential aspect of One Health, and it must be strategically integrated into global One Health frameworks and discussions.
What should be the focus for zoonosis?
Understanding zoonoses through a One Health research lens will help identify evidence gaps, guide targeted interventions, and strengthen integrated approaches to mitigate agrifood-related disease risks.
Coming up
What has been researched so far?
The One Health Joint Plan of Action (2022–2026) advocates for a holistic, integrated approach to One Health covering six priority areas. However, it has not been clear how well current research is aligned to reflect this approach.
An analysis of more than 6000 publications from 2010 to 2024 has mapped One Health publications against the six JPA ‘action tracks’. The study has revealed an exponential increase in research labelled One Health during the period.
Understanding knowledge gaps is crucial for guiding future research direction, helping researchers to ensure their work contributes effectively to integrating different issues within the One Health domain.
The study recommends further efforts by researchers, funders, and policymakers to ensure their work is even better aligned with the broadening scope of One Health.
Find out more
Evidence brief
This research has been conducted by CABI’s One Health Hub, with funding from UK International Development.
Who has implemented this research?
One Health has enjoyed growing popularity over the past two decades. However, it is unclear which countries are conducting research on One Health, the countries where the research is focused, and the extent to which researchers from those countries are involved.
An analysis of more than 6000 research publications has found significant power disparities between One Health researchers in low- and middle-income countries (LMICs) and those in high-income countries (HICs).
Understanding the imbalances in geographical distribution and collaboration in research can help guide work to improve the effectiveness of using One Health to address threats to global health.
Although there has been some progress, more efforts are needed to strengthen One Health research capacity in LMICs. At the same time, the global research community should continue to work together to better understand changes in One Health research priorities, topical gaps and collaborations.
Find Out More
Evidence brief
This research has been conducted by CABI’s One Health Hub, with funding from UK International Development.
Which research topics remain under-explored?
Despite the growing breadth of One Health research, critical topics remain underexplored, limiting the ability of One Health approaches to address complex challenges.
An analysis of more than 6000 research publications has highlighted persistent gaps in research on pesticides, mycotoxins, biodiversity, and land-use change – issues with implications for human, animal, and ecosystem health. These areas are often overlooked despite their relevance to disease emergence, food safety, and environmental degradation.
Identifying and addressing these gaps is essential to ensure that One Health research supports comprehensive, evidence-based interventions.
The study calls for targeted efforts by researchers, funders, and policymakers to expand the scope of One Health research, ensuring that neglected but impactful topics receive the attention they require to inform integrated global health solutions.
Find out more
Evidence brief
This research has been conducted by CABI’s One Health Hub, with funding from UK International Development.
Which regions/countries are underserved?
While One Health research has expanded globally, significant disparities remain in its geographical distribution and authorship.
An analysis of more than 6000 research papers has revealed that research efforts continue to be dominated by high-income countries, with limited representation and leadership from low- and middle-income countries (LMICs). This imbalance affects the ability of One Health initiatives to address region-specific challenges and undermines the inclusivity of solutions.
To ensure locally relevant and globally impactful research, it is essential to strengthen research capacity in LMICs through targeted support and equitable partnerships.
The study calls for inclusive collaboration models that empower LMIC researchers, enabling them to shape research agendas and contribute meaningfully.
Find out more
Evidence brief
This research has been conducted by CABI’s One Health Hub, with funding from UK International Development.
Spotlight on zoonosis: where do we lack evidence and systematic data?
Zoonotic diseases represent a major risk to global health. There is evidence that how we produce, process, and consume food plays a significant role in the occurrence of zoonotic disease. Yet, there are significant research gaps that need to be addressed.
A review of over 400 studies in low- and middle-income countries found that the factors most studied for their influence on zoonotic disease occurrence were host exposure, socio-economic factors, physical and environmental conditions, and domesticated animal management practices. Certain factors, such as exposure to wild animals, were under-investigated, despite their perceived importance in disease occurrence.
Understanding which agrifood-linked factors drive zoonotic disease occurrence and where evidence is lacking is crucial to plan targeted interventions and future research priorities.
Decisionmakers should fund and support integrated, systems-based research, that adopt a One Health approach and examine how agrifood factors interact over time, across hosts, and regions.
Find out more
This research was conducted by the Juno Evidence Alliance and Newcastle University under a collaboration with the One Health Hub and funded by UK International Development.
What priorities should shape future OH research?
Human, animal, plant, and environmental health are deeply interconnected. Despite this, health, agriculture, and ecosystem sectors often operate in isolation. There is a critical need to identify and prioritize research needs for advancing the One Health agenda, especially in low- and middle-income countries.
A global horizon scanning exercise has revealed the top global and regional research priorities. Among these, these top five priorities include: integrated surveillance systems, climate change and emerging diseases, governance mechanisms for One Health, antimicrobial resistance, and socio-environmental drivers of disease.
These findings serve as guidance for policymakers in deciding what research priorities are needed to further One Health and tackle emerging zoonotic diseases.
As a central recommendation, the study calls for effective implementation of the One Health approach to have stronger cross-sector and interdisciplinary coordination, integrated surveillance, and curriculum reform.
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Research paper
This research was conducted by Oxford Systematic Reviews (OXSREV) and funded by UK International Development as part of Juno Evidence Alliance’s work under the One Health Hub.
How to better integrate plant health into One Health?
Plant health remains under-recognized in One Health strategies, despite its formal inclusion in the definition of One Health. This disconnect creates knowledge gaps and limits cross-sectoral synergies.
An analysis highlights how plant health issues – such as pesticide risks, mycotoxins, and invasive species – are deeply intertwined with human, animal, and ecosystem health.
To bridge this gap, the authors recommend redefining One Health to include plant health meaningfully, fostering inclusive collaboration, and aligning funding and policy frameworks to support integrated, cross-domain action.
Find out more
This research was conducted by CABI with funding from UK International Development.
This One Health research roadmap has been produced by
CABI’s One Health Hub with funding from UK International Development.