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Nutrition and Food Sciences

Nutrition and food science information across the food chain supporting academic and industrial research

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Abstract

Higher levels of omega-3 track with longer telomeres, lower inflammation, and blunted sympathetic and cardiovascular stress reactivity. Whether omega-3 supplementation alters the stress responsivity of telomerase, cortisol, and inflammation is unknown. This randomized, controlled trial examined the ...

Author(s)
Madison, A. A.; Belury, M. A.; Andridge, R.; Renna, M. E.; Shrout, M. R.; Malarkey, W. B.; Lin, J.; Epel, E. S.; Kiecolt-Glaser, J. K.
Publisher
Nature Publishing Group, London, UK
Citation
Molecular Psychiatry, 2021, 26, 7, pp 3034-3042
Abstract

Purpose of Review: We discuss current controversies in the clinical use of omega-3 fatty acids (FA), primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and examine discrepancies between recent trials. Furthermore, we discuss potential side effects reported in these studies and...

Author(s)
Quispe, R.; Alfaddagh, A.; Kazzi, B.; Zghyer, F.; Marvel, F. A.; Blumenthal, R. S.; Sharma, G.; Martin, S. S.
Publisher
Springer, New York, USA
Citation
Current Atherosclerosis Reports, 2022, 24, 7, pp 571-581
AbstractFull Text

Background: Long-chain omega-3 and omega-6 fatty acids (n-3, n-6 FAs) may modulate inflammation and affect the risk of developing rheumatoid arthritis (RA). However, whether n-3/n-6 FA status affects RA after disease onset is unknown. This study aimed to assess whether FA profiles are independently ...

Author(s)
Sigaux, J.; Bellicha, A.; Buscail, C.; Julia, C.; Flipo, R. M.; Cantagrel, A.; Laporte, F.; Beal, C.; Boissier, M. C.; Semerano, L.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2022, 14, 14,
Abstract

Importance: It remains uncertain whether the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) reduce cardiovascular risk. Objective: To determine the effects on cardiovascular outcomes of a carboxylic acid formulation of EPA and DHA (omega-3 CA) with documented...

Author(s)
Nicholls, S. J.; Lincoff, A. M.; Garcia, M.; Bash, D.; Ballantyne, C. M.; Barter, P. J.; Davidson, M. H.; Kastelein, J. J. P.; Koenig, W.; McGuire, D. K.; Mozaffarian, D.; Ridker, P. M.; Ray, K. K.; Katona, B. G.; Himmelmann, A.; Loss, L. E.; Rensfeldt, M.; Lundström, T.; Agrawal, R.; Menon, V.; Wolski, K.; Nissen, S. E.
Publisher
American Medical Association, Chicago, USA
Citation
JAMA, Journal of the American Medical Association, 2020, 324, 22, pp 2268-2280
Abstract

Ventilator-induced lung injury (VILI) is an important critical care complication. Nuclear factor-κB (NF-κB) activation, a critical signaling event in the inflammatory response, has been implicated in the tracking of the lung injury. The present study aimed to determine the effect of simultaneous...

Author(s)
Kwack WonGun; Lee YoonJe; Eo EunYoung; Chung JinHaeng; Lee JaeHo; Cho YoungJae
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2021, 13, 7,
Abstract

Objective: To evaluate the effect of polyunsaturated fatty acid-type omega 3 (ω3) on the temporomandibular joint (TMJ) of ovariectomized rats (OVX) with rheumatoid arthritis (RA). Design: Rheumatoid arthritis was induced using complete Freund's adjuvant and type II bovine collagen injected at the...

Author(s)
Marana, R. R.; Santos, V. A. B. dos; Groppo, F. C.; Ferreira, L. E. N.; Sánchez, J. B.; Barbin, T.; Figueroba, S. R.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Archives of Oral Biology, 2022, 134,
Abstract

Background & aims: Docohexanoic acid (DHA), a dietary n-3 polyunsaturated fatty-acid omega-3 (n-3, PUFA), showed potential beneficial effects in reducing all-cause mortality in hemodialysis (HD) patients. This randomized trial aimed to analyze whether DHA supplementation was a modulator of...

Author(s)
Ruperto, M.; Rodríguez-Mendiola, N.; Díaz-Domínguez, M.; Giménez-Moyano, S.; García-Bermejo, M. L.; Fernández-Lucas, M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Clinical Nutrition ESPEN, 2021, 41, pp 129-135
Abstract

Background and aims: Omega-3 fatty acids (FA) can ameliorate the hyper-inflammatory response that occurs in conditions such as severe acute pancreatitis (SAP) and this may improve clinical outcome. We tested the hypothesis that parenteral omega-3 FA from a lipid emulsion that includes fish oil...

Author(s)
Al-Leswas, D.; Eltweri, A. M.; Chung, W. Y.; Arshad, A.; Stephenson, J. A.; Al-Taan, O.; Pollard, C.; Fisk, H. L.; Calder, P. C.; Garcea, G.; Metcalfe, M. S.; Dennison, A. R.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Clinical Nutrition, 2020, 39, 9, pp 2711-2719
Abstract

BACKGROUND: Observational studies suggest vitamin D and marine ω-3 fatty acid (n-3 FA) supplements are associated with lower systemic inflammation. However, past trials have been inconsistent. METHODS: The randomized, double-blind, placebo-controlled VITamin D and OmegA-3 TriaL (VITAL) tested...

Author(s)
Costenbader, K. H.; MacFarlane, L. A.; Lee IMin; Buring, J. E.; Mora, S.; Bubes, V.; Kotler, G.; Camargo, C. A., Jr.; Manson, J. E.; Cook, N. R.
Publisher
American Association for Clinical Chemistry, Washington, USA
Citation
Clinical Chemistry, 2019, 65, 12, pp 1508-1521
Abstract

Preterm labor is associated with inflammation and infection. The mechanisms underlying the role of omega-3 fatty acid in inflammasome activation and prevention of preterm labor remain unknown. We hypothesized that omega-3 fatty acid can reduce the rate of preterm birth induced by infection and...

Author(s)
Chen ChengYi; Chen ChiaYu; Liu ChangChing; Chen ChiePein
Publisher
Portland Press, London, UK
Citation
Clinical Science, 2018, 132, 20, pp 2221-2239

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