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Abstract

Objective: The role of diet in multiple sclerosis (MS) course remains largely unknown. Children with MS have a higher relapse rate compared with MS in adults. Thus, studying the effect of diet on relapse rate in this age group is likely to provide more robust answers. Methods: This is a multicentre ...

Author(s)
Azary, S.; Schreiner, T.; Graves, J.; Waldman, A.; Belman, A.; Guttman, B. W.; Aaen, G.; Tillema, J. M.; Mar, S.; Hart, J.; Ness, J.; Harris, Y.; Krupp, L.; Gorman, M.; Benson, L.; Rodriguez, M.; Chitnis, T.; Rose, J.; Barcellos, L. F.; Lotze, T.; Carmichael, S. L.; Roalstad, S.; Casper, C. T.; Waubant, E.
Publisher
BMJ Publishing Group, London, UK
Citation
Journal of Neurology, Neurosurgery and Psychiatry, 2018, 89, 1, pp 28-33
Abstract

Vitamin D is essential for the maintenance of calcium and phosphorus homeostasis, skeletal growth and various other metabolic processes. The prevalence of vitamin D deficiency in India is 50-90% in various studies. Factors such as low sunlight exposure, age-related decrease in cutaneous synthesis,...

Author(s)
Parminder Singh
Publisher
Association of Physicians of India, Mumbai, India
Citation
Journal of the Association of Physicians of India, 2018, 66, January, pp 75-82
Abstract

Vitamin D deficiency may be associated with depression in the general population. This study aimed to describe the prevalence of depression and anxiety in rheumatoid arthritis (RA) patients from Northwestern China and identify associations of Hamilton Depression Scale (HAMD) and Hamilton Anxiety...

Author(s)
Pu Dan; Luo Jing; Wang YanHua; Ju BoMiao; Lv XiaoHong; Fan Ping; He Lan
Publisher
Springer-Verlag, Godalming, UK
Citation
Clinical Rheumatology, 2018, 37, 1, pp 179-184
Abstract

Objectives: It has been shown that calcitriol and all-trans retinoic acid (ATRA) have modulatory effects on the immune system. The present study investigates the synergistic effects of combination treatment of calcitriol and ATRA in experimental autoimmune encephalomyelitis (EAE), an animal model...

Author(s)
Parastouei, K.; Mirshafiey, A.; Eshraghian, M. R.; Shiri-Shahsavar, M. R.; Solaymani-Mohammadi, F.; Chahardoli, R.; Alvandi, E.; Saboor-Yaraghi, A. A.
Publisher
Taylor & Francis, Abingdon, UK
Citation
Nutritional Neuroscience, 2018, 21, 3, pp 210-218
Abstract

Background: MS is a neurodegenerative autoimmune disease resulting from a complex interaction of genetic and environmental factors. Among these, vitamin D and genetic variants associated with vitamin D-metabolism gain great attention. The aim of our study was to assess five SNPs in NADSYN1 and...

Author(s)
Scazzone, C.; Agnello, L.; Ragonese, P.; Sasso, B. Lo; Bellia, C.; Bivona, G.; Schillaci, R.; Salemi, G.; Ciaccio, M.
Publisher
Wiley, Hoboken, USA
Citation
Journal of Neuroscience Research, 2018, 96, 2, pp 297-304
Abstract

Vitiligo is an acquired autoimmune depigmenting disorder that is the result of white macules formation in the skin and mucous membranes, caused by the loss of melanocytes. It has affected 0.4 to 2.0% of world's population. It has been hypothesized that Vitamin D is important for skin pigmentation,...

Author(s)
Omidian, M.; Pazyar, N.; Mousavi, Z. S.
Publisher
Springer Science + Business Media, London, UK
Citation
Comparative Clinical Pathology, 2018, 27, 3, pp 685-690
Abstract

1,25-dihydroxyvitaminD3 (1,25(OH)2D3), has potent anti-inflammatory effects, including suppression of IL-17+ and IFNγ+T cells implicated in rheumatoid arthritis (RA), but efficacy at the site of active disease is unclear. To investigate this, T cells from synovial fluid (SF) and paired blood of...

Author(s)
Jeffery, L. E.; Henley, P.; Marium, N.; Filer, A.; Sansom, D. M.; Hewison, M.; Raza, K.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Autoimmunity, 2018, 88, pp 50-60
Abstract

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease characterized by destruction of pancreatic beta cells through cell injury caused primarily by cytotoxic T lymphocytes (CD8+). The pathophysiological basis of T1DM seems to be an imbalance between a reduced function of T regulatory...

Author(s)
Pinheiro, M. M.; Pinheiro, F. M. M.; Trabachin, M. L.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
International Immunopharmacology, 2018, 57, pp 11-17
Abstract

Background: Vitamin D deficiency has been associated with systemic lupus erythematosus (SLE), but there is no consensus on the role of serum vitamin D in evaluating or predicting disease activity. This study aimed to demonstrate the direct correlation between vitamin D level and pediatric-onset SLE ...

Author(s)
Lin TingChun; Wu JhongYong; Kuo MingLing; Ou LiangShiou; Yeh KuoWei; Huang JingLong
Publisher
Elsevier Taiwan LLC, Taipei, Taiwan
Citation
Journal of Microbiology, Immunology and Infection, 2018, 51, 1, pp 110-114
Abstract

The Irish population is at risk of vitamin D deficiency during the winter months, but the secular trend over the past 40 years is for marked improvement. Multiple sclerosis (MS) is common in Ireland with a latitudinal pattern favouring highest incidence in northern regions; MS is linked strongly...

Author(s)
McKenna, M. J.; Murray, B.; Lonergan, R.; Segurado, R.; Tubridy, N.; Kilbane, M. T.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Steroid Biochemistry and Molecular Biology, 2018, 177, pp 91-95

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