Background: Vitamin D insufficiency is associated with risk of multiple sclerosis (MS) relapse; whether supplementation influences prognosis is unknown. The Vitamin D to Ameliorate MS (VIDAMS) trial aimed to determine if high dose (5000 International Units (IU)/day) versus low dose (600 IU/day)...
Author(s)
Cassard, S. D.; Fitzgerald, K. C.; Qian, P.; Emrich, S. A.; Azevedo, C. J.; Goodman, A. D.; Sugar, E. A.; Pelletier, D.; Waubant, E.; Mowry, E. M.
Publisher
Lancet Limited, London, UK
Citation
EClinicalMedicine, 2023, 59,
One-third of boys with X-linked adrenoleukodystrophy (ALD) develop inflammatory demyelinating lesions, typically at the splenium. These lesions share similarities with multiple sclerosis, including cerebral hypoperfusion and links to vitamin D insufficiency. We hypothesized that increasing vitamin...
Author(s)
Zhao, M. Y.; Dahlen, A.; Ramirez, N. J.; Moseley, M.; Haren, K. van; Zaharchuk, G.
Publisher
Wiley, Hoboken, USA
Citation
Journal of Neuroscience Research, 2023, 101, 7, pp 1086-1097
Calcium is imperative in maintaining a quality life, particularly during later ages. Its deficiency results in a wide range of metabolic disorders such as dental changes, cataracts, alterations in brain function, and osteoporosis. These deficiencies are more pronounced in females due to increased...
Author(s)
Aftab Ahmed; Saleem, M. A.; Farhan Saeed; Muhammad Afzaal; Ali Imran; Sidra Akram; Muzzamal Hussain; Aqsa Khan; Al-Jbawi, E.
Publisher
Wiley Periodicals LLC, Hoboken, USA
Citation
Food Science & Nutrition, 2023, 11, 9, pp 5004-5027
Vitamin D (VD) is the most discussed antioxidant supplement for multiple sclerosis (MS) patients and many studies suggest correlations between a low VD serum level and onset and progression of the disease. While many studies in animals as well as clinical studies focused on the role of VD in the...
Author(s)
Haindl, M. T.; Üçal, M.; Wonisch, W.; Lang, M.; Nowakowska, M.; Adzemovic, M. Z.; Khalil, M.; Enzinger, C.; Hochmeister, S.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2023, 15, 15,
Psoriasis is a chronic immune-dysregulated inflammatory disease and hypovitaminosis D is considered a risk factor. We conducted an online database search to review and meta-analyze the relationship between vitamin D, other bone metabolism parameters, and psoriasis. The efficacy of oral vitamin D...
Author(s)
Formisano, E.; Proietti, E.; Borgarelli, C.; Pisciotta, L.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2023, 15, 15,
Background: The role of vitamin D (25(OH)D) in the pathogenesis and outcome of several conditions, including autoimmune diseases, diabetes and cancers is largely described in the literature. The aims of this study were to evaluate the prevalence of 25(OH)D deficit in a cohort of patients with...
Author(s)
Albertelli, M.; Petolicchio, C.; Brasili, S.; Pogna, A.; Boschetti, M.; Luciano, G.; Campana, D.; Gay, S.; Veresani, A.; Ferone, D.; Vera, L.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2023, 15, 17,
Both 25-autoimmunity and(25(OH)D: calcifediol) and its active form, 1,25-dihydroxyvitamin D (1,25(OH)2D: calcitriol), play critical roles in protecting humans from invasive pathogens, reducing risks of autoimmunity, and maintaining health. Conversely, low 25(OH)D status increases susceptibility to...
Author(s)
Wimalawansa, S. J.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2023, 15, 17,
Better knowledge about the possible role of genetic factors in modulating the response to multiple sclerosis (MS) treatment, including rehabilitation, known to promote neural plasticity, could improve the standard of care for this disease. Vitamin D receptor (VDR) gene polymorphisms are associated...
Author(s)
Guerini, F. R.; Agliardi, C.; Oreni, L.; Groppo, E.; Bolognesi, E.; Zanzottera, M.; Caputo, D.; Rovaris, M.; Clerici, M.
Publisher
MDPI AG, Basel, Switzerland
Citation
International Journal of Molecular Sciences, 2023, 24, 17,
Objective: To describe the frequency of malnutrition in older patients with rheumatoid arthritis (RA) and investigate associated risk factors. Methods: This multicenter, cross-sectional study included participants aged ≥65 years who met the 2010 ACR/EULAR criteria for RA. Nutritional status was...
Author(s)
Cano-García, L.; Redondo-Rodríguez, R.; Manrique-Arija, S.; Domínguez-Quesada, C.; Vacas, J. C.; Armenteros-Ortiz, P.; Ruiz-Vilchez, D.; Martín-Martín, J. M.; García-Studer, A.; Ortiz-Márquez, F.; Mena-Vázquez, N.; Fernández-Nebro, A.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2023, 15, 16,
BACKGROUND: Vitamin D deficiency is associated with an increased risk and progression of the disease, especially sepsis. Low serum Vitamin D levels when patients enter the Intensive Care Unit (ICU) can affect patient care outcomes. AIM: This study aims to determine the relationship between Vitamin...
Author(s)
Kahar, L. A.; Yusrawati, Y.; Jamsari, J.; Maskoen, T.
Publisher
ID Design, Skopje, Republic of Macedonia
Citation
Open Access Macedonian Journal of Medical Sciences, 2023, 11, B, pp 122-127