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Nutrition and Food Sciences

Nutrition and food science information across the food chain supporting academic and industrial research

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Abstract

Hashimoto's thyroiditis (HT) is the most common autoimmune disease and the leading cause of hypothyroidism, in which damage to the thyroid gland occurs due to the infiltration of lymphocytes. It is characterized by increased levels of antibodies against thyroid peroxidase and thyroglobulin. In this ...

Author(s)
Mikulska, A. A.; Karaźniewicz-Łada, M.; Filipowicz, D.; Ruchała, M.; Główka, F. K.
Publisher
MDPI AG, Basel, Switzerland
Citation
International Journal of Molecular Sciences, 2022, 23, 12,
Abstract

Objective: To investigate whether vitamin D and marine derived long chain omega 3 fatty acids reduce autoimmune disease risk. Design: Vitamin D and omega 3 trial (VITAL), a nationwide, randomized, double blind, placebo controlled trial with a two-by-two factorial design. Setting: Nationwide in the...

Author(s)
Hahn, J.; Cook, N. R.; Alexander, E. K.; Friedman, S.; Walter, J.; Bubes, V.; Kotler, G.; Lee IMin; Manson, J. E.; Costenbader, K. H.
Publisher
BMJ Publishing Group, London, UK
Citation
The BMJ, 2022, 376, e066452,
AbstractFull Text

The popularization of the gluten-free diet brings with it a fashion for its use, which can harm the treatment of Hashimoto's disease. The few studies in this regard do not confirm positive changes resulting from a gluten-free diet. At the same time, the presence of other comorbid autoimmune...

Author(s)
Szczuko, M.; Syrenicz, A.; Szymkowiak, K.; Przybylska, A.; Szczuko, U.; Pobłocki, J.; Kulpa, D.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2022, 14, 9,
AbstractFull Text

In October 2019, the Italian Drug Agency (AIFA) restricted reimbursement criteria for vitamin D (VD) use outside the osteoporosis setting (Note 96). However, whether this restriction could also have involved patients at risk for or with osteoporotic fractures has not yet been investigated. We...

Author(s)
Esposti, L. D.; Perrone, V.; Sella, S.; Arcidiacono, G.; Bertoldo, F.; Giustina, A.; Minisola, S.; Napoli, N.; Passeri, G.; Rossini, M.; Giannini, S.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2022, 14, 9,
AbstractFull Text

A worldwide high prevalence of vitamin D (VD) deficiency has become of growing concern because of potential adverse effects on human health, including pregnant women and their offsprings. Beyond its classical function as a regulator of calcium and phosphate metabolism, together with its fundamental ...

Author(s)
Mansur, J. L.; Oliveri, B.; Giacoia, E.; Fusaro, D.; Costanzo, P. R.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2022, 14, 9,
Abstract

Ischemia reperfusion (I/R) injuries occurred in many pathological and surgical processes (e.g. thrombolytic therapy, organ transplantation, aortic cross-clamping, coronary angioplasty and cardiopulmonary bypass) and harmed multiple organs and tissues. Vitamin D is a well-known sterol hormone and a...

Author(s)
Chen ChaoRan; Wan Xiao; Shang Jia; Zhang WuNong; Xie ZhenXing
Publisher
Taylor & Francis, Philadelphia, USA
Citation
International Journal of Food Properties, 2022, 25, 1, pp 522-540
AbstractFull Text

Vitamin D has been implicated in the pathogenesis of skeletal disorders and various autoimmune disorders. Vitamin D can be consumed from the diet or synthesized in the skin upon ultraviolet exposure and hydroxylation in the liver and kidneys. In its bioactive form, vitamin D exerts a potent...

Author(s)
Wu ChaoYi; Yang HuangYu; Luo ShueFen; Huang JingLong; Lai JennHaung
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2022, 14, 8,
AbstractFull Text

Background: In 2013, the group of Cicero Coimbra, Brazil, reported the clinical efficacy of high doses of vitamin D3 in patients suffering from autoimmune skin disorders ("Coimbra protocol", CP). However, hypercalcemia and the subsequent impaired renal function may be major concerns raised against...

Author(s)
Amon, U.; Yaguboglu, R.; Ennis, M.; Holick, M. F.; Amon, J.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2022, 14, 8,
Abstract

Objectives: To investigate the profile of autoimmune markers and to evaluate the status of vitamin D in the autoimmune process in brucellosis. Study Design: Descriptive study. Place and Duration of Study: Department of Rheumatology and Microbiology-Basic Immunology, Balikesir Ataturk City Hospital, ...

Author(s)
Cuzdan, N.; Duran, A. C.; Atik, T. K.
Publisher
College of Physicians and Surgeons Pakistan, Karachi, Pakistan
Citation
JCPSP, Journal of the College of Physicians and Surgeons Pakistan, 2022, 32, 4, pp 503-509
Abstract

Type 1 diabetes (T1D) is a chronic autoimmune disease accompanied by the immune-mediated destruction of pancreatic β-cells. In this study, we aimed to explore the regulatory effects of vitamin D (VD) supplementation on pancreatic β-cell function by altering the expression of bioinformatically...

Author(s)
Lai XiaoYang; Liu XuYang; Cai Xia; Zou Fang
Publisher
American Physiological Society, Bethesda, USA
Citation
American Journal of Physiology - Endocrinology and Metabolism, 2022, 322, 1, pp E74-E84

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