Objective: To study the effects of sodium alginate and its oligosaccharide on lipid metabolism and intestinal flora in mice. Methods: C57BL/6 mice were used to make a high-fat model and fed with sodium alginate and its oligosaccharide. The physiological and biochemical indexes such as body weight...

BACKGROUND: Effects of soy-containing infant formulas on the thyroid gland is not clear. We aimed to evaluate the effects of infant formulas with different quantities of soy content on the functional and histopathological characteristics of the thyroid gland. METHODS: Twenty-eight female...

Background: Inducible brown adipocytes called beige adipocytes are found in white adipose tissue (WAT) depots. They express functional UCP1 and have thermogenic fat-burning capacities as also found in classical brown adipocytes in response to various stimuli. Beige adipocytes may also secrete...

Uncoupling protein 1 (UCP1) executes thermogenesis in brown adipose tissue, which is a major focus of human obesity research. Although the UCP1-knockout (UCP1 KO) mouse represents the most frequently applied animal model to judge the anti-obesity effects of UCP1, the assessment is confounded by...

This special issue contains 11 articles that features original, clinical and basic research in the fields of neurophysiology and functional imaging, neuropharmacology and neurochemistry, neuroendocrinology and neuroimmunology, genetics and their relationships with normal psychology and...

The imbalance between osteoclastic bone resorption and osteoblastic bone formation due to inflammation and oxidative stress contributes to bone loss and osteoporosis. In this regards, dietary antioxidative and anti-inflammatory compounds may delay the progression of osteoporosis. Coenzyme Q10 is an ...

Obesity and overweight have become serious health problems in the world and are linked to a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely studied for the past few decades. Capsaicin is the major bioactive component in red chili peppers with many...

The coffee diterpene kahweol may contribute to the anti-obesity effects of coffee but its physiological effects have yet to be elucidated. Caenorhabditis elegans is used as an animal model in obesity research because its lipid metabolism is conserved in humans. The goal was to investigate kahweol's ...

Aims: Investigate the role of melatonin on the regulation of body temperature in aged animals that have impaired melatonin production. Material and methods: Aged Male Wistar rats were randomly assigned to the following groups: (1) control (vehicle added to the water bottles during the dark phase)...

Objective: To investigate the effect of egg yolk or soy-derived phospholipids on lipids metabolism in rats fed a high-fat diet. Methods Twenty four male Sprague Dawley rats were randomly divided into 4 groups: control, high-fat model, high-fat diet with cgg yolk phospholipids (Egg-PL), and high-fat ...