Polysaccharides from Laminaria japonica (LJPs) are reported to have various functional properties, but the effects and mechanisms of LJPs on obesity and its related diseases are unclear. This study demonstrated that LJPs prevented diet-induced obesity in a mice model, and improved obesity-related...

The major goals of this research were to evaluate ethanolic extracts from Phyllanthus niruri and Phyllanthus acidus in a number of animal models for their early antihyperglycemic and anti-hyperlipidemic effects. The present study looked at the effects of ethanolic extracts from Phyllanthus niruri...

The objective of the study was to determine the wound healing activity of the Clitoria ternate L. flower ethanolic extract in the gel preparation in a diabetic animal model. We conducted an optimization of the gel preparations from various concentration of carbomer (0, 5%, 1%, 1.5%, 2%) and...

Ethnopharmacological relevance: Opuntia speciesis used in traditional medicine to treat diabetes mellitus (DM). Polysaccharide is one of the main components of Opuntia. Opuntia polysaccharide (OPS) is a kind of natural active macromolecular substance, numerous animal experiments have been conducted ...

Background/Aim: We examined the inhibitory effect of mulberry leaf (ML) (Morus alba L.) administration on the development of hepatocellular carcinoma (HCC) in stelic animal model (STAM) mice. This STAM mouse model of nonalcoholic steatohepatitis (NASH) closely resembles the progression from NASH to ...

Ethnopharmacological relevance: Ardisiaelliptica Thunb. (AE) (Primulaceae) is a medicinal plant found in the Malay Peninsula and has been traditionally used to treat diabetes. However, limited studies to date in providing scientific evidence to support the antidiabetic efficacy of this plant by ...

Ethnopharmacological relevance: Qinlian Hongqu decoction (QLHQD) is a traditional Chinese medicine (TCM) formula. It has previously been found to mitigate hyperlipidemia, although its mechanism requires further clarification. Aim of the study: This study explored QLHQD's mechanism in treating...

Stevia (Stevia rebaudiana Bertoni) is an aromatic plant known for its high sweetening power ascribed to its glycosides. Stevia also contains several bioactive compounds showing antioxidant, antiproliferative, antimicrobial, and anti-inflammatory activities. Since inflammation and oxidative stress...

Objective: In this study, we aimed to determine the role of Psidium cattleianum extract (PCE) and compare its effects with those of metformin (Met) in an animal model with type 2 diabetes mellitus (T2DM). Methods: T2DM was induced in rats using a high-fat diet (HFD), followed by a single dose of...

Aegle Marmelos is a traditional medicinal plant in India which belongs to Rutaceae family which possesses innumerable health benefits. The entire plant body including its leaves, stem, root, inflorescence and seed are proved to be significant medicinal value and hence it is one among the inevitable ...