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Nutrition and Food Sciences

Nutrition and food science information across the food chain supporting academic and industrial research

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Abstract

Aged rhesus monkeys, like aged humans, show declines in cognitive function. We present cognitive test data from a large sample of male and female rhesus monkeys, 34 young (aged 3.5-13.6 years) and 71 aged (aged 19.9-32.5 years at the start of cognitive testing). Monkeys were tested on...

Author(s)
Baxter, M. G.; Roberts, M. T.; Roberts, J. A.; Rapp, P. R.
Publisher
Elsevier, New York, USA
Citation
Neurobiology of Aging, 2023, 130, pp 40-49
Abstract

The main etiological mechanism for Kashin-Beck disease (KBD) is deep chondrocyte necrosis induced by environmental risk factors (ERFs). The scholars have conducted several epidemiological, cellular, and animal model studies on ERFs. Gradually, four etiological hypotheses have been formed, including ...

Author(s)
Yu FangFang; Zuo Juan; Sun Lei; Yu ShuiYuan; Lei XiaoLi; Zhu JunHua; Zhou GuoYu; Guo Xiong; Ba Yue
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Ecotoxicology and Environmental Safety, 2022, 234,
Abstract

Diet as a whole, encompassing food composition, calorie intake, and the length and frequency of fasting periods, affects the time span in which health and functional capacity are maintained. Here, we analyze aging and nutrition studies in simple organisms, rodents, monkeys, and humans to link...

Author(s)
Longo, V. D.; Anderson, R. M.
Publisher
Cell Press, Cambridge, USA
Citation
Cell (Cambridge), 2022, 185, 9, pp 1455-1470
Abstract

Age-related impairments in cognitive function occur in multiple animal species including humans and nonhuman primates. Humans and rhesus monkeys exhibit a similar pattern of cognitive decline beginning in middle age, particularly within the domain of executive function. The prefrontal cortex is the ...

Author(s)
Uprety, A.; Moss, M. B.; Rosene, D. L.; Killiany, R. J.; Moore, T. L.
Publisher
American Psychological Association, Inc., Washington DC, USA
Citation
Behavioral Neuroscience, 2022, 136, 2, pp 126-138
Abstract

Objectives: This systematic review aimed to assess whether hard or soft foods interfere with the pattern of occlusal changes in nonhuman mammals. Design: The electronic databases PubMed, Scopus, Web of Science, Cochrane Library, LILACS, OpenGrey and Google Scholar were examined. Only studies...

Author(s)
Bastos, R. T. da R. M.; Mecenas, P.; Normando, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Archives of Oral Biology, 2021, 130,
Abstract

Arguably, the most important discovery in the biology of aging to date was that simply reducing food intake extended life and improved many aspects of health in a diversity of animal species. The conventional wisdom that emerged from first 50 years of rodent food restriction studies included (1)...

Author(s)
Austad, S. N.; Hoffman, J. M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Current Opinion in Biotechnology, 2021, 70, pp 56-60
Abstract

Aim: Opioid-targeted vaccines are under consideration as candidate Opioid Use Disorder medications. We recently reported that a fentanyl-targeted vaccine produced a robust and long-lasting attenuation of fentanyl-vs-food choice in rats. In the current study, we evaluated an optimized...

Author(s)
Townsend, E. A.; Bremer, P. T.; Jacob, N. T.; Negus, S. S.; Janda, K. D.; Banks, M. L.
Publisher
Elsevier, New York, USA
Citation
Drug and Alcohol Dependence, 2021, 218,
Abstract

Sensitivity to satiety constitutes a basic requirement for neuronal coding of subjective reward value. Satiety from natural ongoing consumption affects reward functions in learning and approach behavior. More specifically, satiety reduces the subjective economic value of individual rewards during...

Author(s)
Pastor-Bernier, A.; Stasiak, A.; Schultz, W.
Publisher
National Academy of Sciences, Washington DC, USA
Citation
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118, 30,
Abstract

Myocardial ischemia leads to cardiac fibrosis along with copper (Cu) loss. Cu repletion diminishes myocardial fibrosis and improves cardiac function. The transformation of fibroblasts to myofibroblasts is highly responsible for the pathogenesis of cardiac fibrosis. This study was undertaken to test ...

Author(s)
Xiao Ying; Feng QiPu; Huang Lu; Meng Xia; Han PengFei; Zhang WenJing; Kang James [Kang, J. Y.]
Publisher
Elsevier, New York, USA
Citation
Journal of Nutritional Biochemistry, 2023, 111,
AbstractFull Text

Hsp70.1 has a dual function as a chaperone protein and lysosomal stabilizer. In 2009, we reported that calpain-mediated cleavage of carbonylated Hsp70.1 causes neuronal death by inducing lysosomal rupture in the hippocampal CA1 neurons of monkeys after transient brain ischemia. Recently, we also...

Author(s)
Yamashima, T.; Mori, Y.; Seike, T.; Ahmed, S.; Boontem, P.; Li, S.; Oikawa, S.; Kobayashi, H.; Yamashita, T.; Kikuchi, M.; Kaneko, S.; Mizukoshi, E.
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2023, 15, 8,

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