Two turmeric food powders (C1 and C2) were studied for curcuminoid content and their effects on the guinea pig intestinal tract in vitro. C1 contained a higher curcuminoid content than C2 (5.22% vs 2.31%). C1 and C2 increased gallbladder (~10%) and biliary smooth muscle tone (~15%), without...

Vitamin C or ascorbic acid is a required nutrient for humans. Should this vitamin be lacking in the human diet, the disease, scurvy, will develop. Scurvy has been described since ancient times, and its cure through the provision of ascorbic acid has had a torturous path. Vitamin C is an important...

Background: Intrauterine growth restriction (IUGR) exerts a negative impact on developing cardiomyocytes and emerging evidence suggests activation of oxidative stress pathways plays a key role in this altered development. Here, we provided pregnant guinea pig sows with PQQ, an aromatic tricyclic...

In order to provide a reference for the prevention and control of myopia through nutritional means, the protective effect of medium-chain triacylglycerol (MCT) on myopia in guinea pigs with high sucrose diet was investigated. Three-week-old guinea pigs were randomly divided into MCT group,...

Identifying how specific nutrients can impact fertility, pregnancy, and neonatal outcomes will yield important insights into the biological mechanisms linking diet and reproductive health. Our study investigates how dietary vitamin C intake affects various fertility parameters and pregnancy and...

Objective To observe the effect of YNS skin-nourishing cream for the improvement and repair of damaged skin and its influence on the intestinal flora of guinea pigs. Methods Twenty-four guinea pigs were randomly divided into four groups: Control group, Positive control group, Cosmetic group and...

Nonalcoholic fatty liver disease (NAFLD) is intricately linked to metabolic disease (including obesity, glucose intolerance, and insulin resistance) and encompasses a spectrum of disorders including steatosis, nonalcoholic steatohepatitis (NASH), and fibrosis. Rodents consuming high-fat (HF; ~40...

We investigated the potential inhibitory effects of docosahexaenoic acid (DHA) on the contractions of guinea pig tracheal smooth muscles in response to U46619 (a thromboxane A₂ (TXA₂) mimetic) and prostaglandin F_2α (PGF_2α) to examine whether this n-3 polyunsaturated fatty acid suppresses...

The retina requires docosahexaenoic acid (DHA) for optimal function. Alpha-linolenic acid (ALA) and DHA are dietary sources of retinal DHA. This research investigated optimizing retinal DHA using dietary ALA. Previous research identified 19% DHA in retinal phospholipids was associated with optimal...

Background: Olive oil is a natural source of phytoestrogens and antioxidants similar to mammalian estrogen. The substance increases osteoblast differentiation and osteoprotegerin (OPG) expression. Objective of the study: To examine the effect of giving olive oil on OPG expression of gingival...