Peronema canescens has traditionally been used by the community of Musi Banyuasin, South Sumatera, Indonesia, to treat hypertension. One of the triggers for hypertension is high levels of blood cholesterol. The in vivo research on the antihyperlipidemia activity of the ethanol extract P. canescens...

Whether polycyclic aromatic hydrocarbons (PAHs) exposure is associated with muscle mass and muscle strength has been scantly investigated. The cross-sectional associations of urinary PAH metabolites with appendicular skeletal muscle mass and hand grip strength in adults were first investigated in...

Dyslipidemia substantially contributes to the risk of cardiovascular diseases. The polyherbal formulation has been a traditional therapeutic strategy used to treat dyslipidemia. This study was designed to evaluate the effects of a novel herbal medicine called "GANMO" on an experimental animal model ...

Objective: This study aims at evaluating the anti-diabetic, hypolipidemic, and pancreatic histopathological changes of Rhizophora mucronata and Avicennia marina. Materials and Methods: The experimental rats were divided into eight groups (n = 15 each). Streptozotocin was used to induce diabetes....

Objective: To study the hypoglycemic effect of Lithocarpus polystachyus and its mechanism. Methods: Diabetic rat model induced by high-fat diet feeding and Streptozotocin Injection, Through giving the Lithocarpus polystachyus extract to observe the effect of polycotyledon extract on body weight,...

The effects of curcumin on the bioavailability of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) were investigated in Sprague-Dawley rats. Tetraand penta-chlorinated PCDFs had the lowest bioavailability and hexa-chlorinated PCDD/Fs had the...

Chinese yam is the dry rhizome of dioscoreaceae plant. Polysaccharide in yam is one of significant functional components, its pharmacological effects include glucose-lowering, lipid-lowering, anti-tumor, anti-oxidation and enhancing the immune. The effects of nano yam polysaccharide on the...

Helicid suppresses inflammatory factors and protects nerve cells in the hippocampus of rats with depression, but the mechanisms underlying its protective effects are unclear at present. In this investigation, we conducted gene silencing, Helicid intervention and rescue experiments to explore the...

In this study, we investigated the chemical profile and effects of RW0117 (Artemisia argyi 6 5.5% ethanol extract) on gastric lesions in rats. We optimized and validated a method to obtain the chemical profile of RW0117. We then investigated the antioxidant and anti-inflammatory effects in vitro,...

The study aimed to investigate the nephroprotective and cardioprotective effects of ethanol extract of litchi leaf (LI) in two-kidney-one-clip (2K1C) rat model. HPLC analysis revealed the presence of several polyphenolic antioxidants in LI. Correspondingly, LI at 50-200 mg/kg reduced the level of...