Objective: This study was conducted to explore the effects and possible mechanisms of citric acid and acetic acid on the contraction of isolated mouse intestinal smooth muscle, and to provide references for the development of organic acid products that helps regulate gastrointestinal motility...

Acute toxicity and subacute toxicity of fish oil and curcuma extractum was evaluated by animal test to ensure the edible safety. The acute oral toxicity test of mice and rats and 30-day feeding test on rats were performed. The results showed that, the MTD for mice and rats was more than 15 000...

Gastrointestinal tract plays a critical role in human health, in which intestinal microflora, immune barrier, and metabolic circulation are closely related to the physiological function of the body. Prebiotics are not digested and absorbed by the host, and can selectively promote the proliferation...

The milk fat globule membrane (MFGM) is a three-layer membrane structure that surrounds milk fat globules. The structure of fat globules in cow milk-based and soy-based infant formulas, lacking MFGM, is quite different from that in human milk. Therefore, addition of exogenous MFGM and preparation...

Objective: To evaluate sub-acute oral toxicity of L-arabinose in rats. Methods: According to GB 15193.22-2014 National food safety standard-Repeated dose 28-day oral toxicity study, specific pathogen free (SPF) grade healthy Sprague-Dawley (SD) rats were selected and divided randomly based on their ...

Objective: To evaluate, the effects of saccharose and fructose on colon bacteria composition. Method: Male SD rats were equally and randomly divided into 3 groups: (1) control group (fed sugar-free diet, Control), (2) 13.2% fructose diet (Fru), (3) 13.2% saccharose diet (Sac). After 20 weeks, all...

Objective: To study the effects of sodium alginate and its oligosaccharide on lipid metabolism and intestinal flora in mice. Methods: C57BL/6 mice were used to make a high-fat model and fed with sodium alginate and its oligosaccharide. The physiological and biochemical indexes such as body weight...

Conjugated linoleic acid, a mixture of eighteen carbon polyunsaturated fatty acid with conjugated double bonds, has many activities in weight loss and fat reduction of the body and verifiable clinical safety, which makes it become one of the hotspots among the international market of losing weight. ...

Edible bird's nest(EBN) is made of saliva secreted by specific swiftlets mixed with feathers and has been regarded as the most prized health delicacy and medicine among Chinese community. Female is the major consumer group of EBN. However, there is still a lack of comprehensive and sufficient...

The number of patients with alcoholic liver disease has increased over time, but the mechanism that induce this disease are still unclear. Therefore, it's important to establish an animal model of alcoholic liver disease as a follow-up study. This study reviewed the NIAAA method and attempted to...