To study the lipid-lowering effect of walnut green husk on mice with acute hyperlipidemia. The experimental mice were randomly divided into the following groups according to body weight:normal,model, fenofibrate groups, and walnut green husk extract low-dose,medium-dose,high-dose groups. After...

Bisphenol P (BPP), structurally similar to bisphenol A, is commonly identified in the samples of environment, food, and humans. Unfortunately, very little information is currently available on adverse effects of BPP. The obesogenic effects and underlying mechanisms of BPP on mice were investigated...

More and more evidence has supported the interaction between circadian rhythms and intestinal microbes, which provides new insights into how dietary nutrition can improve host health. Our research showed that Ficus pandurata Hance var. angustifolia Cheng flavonoids (FCF) ameliorated the...

In this study, the oligosaccharide crude extract was prepared from cow milk. The contents of total sugar and reducing sugar in milk oligosaccharide crude extract were detected by phenol concentrated sulfuric acid method and DNS method, so the polysaccharide content in the crude extract were...

The effects of selenium on serum cytokines, immune cell composition and spleen proteome in mice are still unclear. In this study, male mice were fed with selenium-containing diets for eight weeks, and serum cytokines were assayed using Luminex liquid suspension chip. The spleen was obtained for...

Green tea polyphenols (GTP) have similar activities as prebiotics, which effectively regulate the structure of intestinal flora and affect their metabolic pathways. The intestinal flora is closely related to the host's circadian rhythm, and the supplementation with GTP may be an effective way to...

Microglia-mediated neuroinflammation is closely related to depression. Many studies have shown that the NF-κB pathway was involved in the anti-neuroinflammatory effects of luteolin. However, more detailed molecular mechanisms should be further studied. In this study, our data indicated that...

We recently reported that dopamine D3 receptor (D3R) was involved in inflammation-related depression. Nucleus accumbens (NAc) inflammation is implicated in the development and progression of depression, but its regulatory mechanism remains largely unknown. In a mouse model of NAc neuroinflammation...

Under the control of the host circadian rhythms, intestinal microbiota undergoes dietary-dependent diurnal fluctuations in composition and function. In addition, microbiome plays a critical role in maintaining the host circadian rhythms and metabolic homeostasis. The interactions between host...

Mitochondrial reactive oxygen species (ROS)generation plays an essential role in the process of adipocyte differentiation and is involved in the development of obesity and associated metabolic diseases. Various dietary flavonoids possess the substantial anti-adipogenic activity. However, it is...