Objective: To investigate the effect of egg yolk or soy-derived phospholipids on lipids metabolism in rats fed a high-fat diet. Methods Twenty four male Sprague Dawley rats were randomly divided into 4 groups: control, high-fat model, high-fat diet with cgg yolk phospholipids (Egg-PL), and high-fat ...

To investigate the effects of stevia extract on lipid metabolism, oxidative stress and intestinal microecology. We chose healthy Kunming mice, built models of lipid metabolic disorders, and examined changes in blood lipids, oxidative stress, and intestinal flora. Stevia extract significantly...

Due to the high addiction and side effects of medicines, people have increasingly inclined to natural and healthy peptides to improve sleep. Herein, we isolated novel peptides with sleep-promoting ability from Pneumatophorus japonicus bone peptides (PBPs) and constructed an insomniac zebrafish...

Objective: To investigate the mechanism of carvacrol alleviating oxidative stress damage in rats with diabetic nephropathy (DN) via the SIRT1/FOXO1 pathway. Methods: A rat model of DN was established by high-fat diet and intraperitoneal injection of streptozotocin, and then DN rats were divided...

Diabetic gastroparesis is a common complication of diabetes that may lead to poor nutrition, problems managing blood glucose, and a reduced quality of life. Jiawei Sijunzi soup has been shown to benefit patients with amyotrophic lateral sclerosis while causing no serious side effects. In this...

Nanoplastics have become ubiquitous in the global environment and have attracted increasing attention. However, whether there is an influence between exposure to nanoplastics and diabetes is unclear. To determine the effects of exposure to Polystyrene nanoplastics (PS-NPs) and evaluate the...

Scope: Insulin resistance is a common feature of obesity and type 2 diabetes and partly results from an imbalance between food intake and energy expenditure. Therefore, efficient and safe insulin resistance treatment therapies are warranted. This work is aim to access the impact of protocatechuic...

Suppression of excessive inflammatory responses improves the survival of patients with sepsis. We previously illustrated the anti-inflammatory effects of fucoxanthin (FX), a natural carotenoid isolated from brown algae; nevertheless, the underlying mechanism remains unknown. In this study, we...

Research shows that reduced sleep duration is related to an increased risk of obesity. The relationship between sleep deprivation and obesity, type 2 diabetes, and other chronic diseases may be related to the imbalance of appetite regulation. To comprehensively illustrate the specific relationship...

Secreted frizzled-related protein (SFRP) 4 is an extracellular antagonist of Wnt signalling that regulates adipogenesis, and is highly in the visceral adipose tissue of obese individuals. However, it is still unclear how exactly SFRP4 regulates the secretion of adipokines in the adipose tissue in...