Neurological disorders are diverse, have complex causes, and often result in disability; yet, effective treatments remain scarce. The resveratrol derivative pterostilbene possesses numerous physiological activities that hold promise as a novel therapy for the central nervous system (CNS) disorders. ...

In order to enhance the loading of naringin (NA) in OSA modified porous starch (OSAPS) by optimization experiments and further enhance the in vivo bioavailability of NA with the form of complex, OSAPS-NA complexes were prepared by antisolvent precipitation method and metabolic kinetic studies were...

Fluorescent probe labeling is easy to operate and the sensitivity of fluorescence detection is 3-4 orders of magnitude higher than traditional methods such as ultraviolet visible (UV-Vis) spectroscopy. The absorption and distribution of chitosan oligosaccharide (COS) monomers with different degrees ...

Severe heat exposure causes mitochondrial fragmentation and dysfunction, which contribute to the pathogenesis of heat-related illness. L-Citrulline is a naturally occurring amino acid and has been suggested to influence heat shock responses. This study aimed to test whether L-citrulline...

Pulmonary fibrosis (PF) is an interstitial lung disease characterized by the destruction of the pulmonary parenchyma caused by excessive extracellular matrix deposition. Despite the well-known etiological factors such as senescence, aberrant epithelial cell and fibroblast activation, and chronic...

The first oral form of the glucagon-like peptide-1 receptor agonist, oral semaglutide, has recently been launched and potently controls glycemia and body weight in subjects with type 2 diabetes. This drug carries the absorption enhancer and requires specific protocols of administration. The...

The tea of roasted Highland barley is a cereal-based drink rich in polyphenols. A model of skeletal muscle senescence and fibrosis was constructed using d-galactose-induced C2C12 myotubes, and Highland barley tea Polyphenols (HBP) were extracted for the intervention. We found that HBP effectively...

Intermittent fasting (IF) is a dietary strategy that involves alternating periods of abstention from calorie consumption with periods of ad libitum food intake and has been shown to have beneficial effects in many ways. Recent studies have shown that IF attenuates neurodegeneration and improves...

Marginal zinc deficiency is more common than severe zinc deficiency, and the effect of marginal zinc deficiency on male reproduction is unknown. This study investigated the effect of marginal zinc deficiency on spermatogenesis and its mechanism. Male ICR mice were fed normal zinc (30 mg/kg) and...

The intervention effects of royal jelly, its crude protein fractions and its functional protein and lipid extracts on insomnia were investigated. Dialysis ultrafiltration, vacuum freeze -drying and methanol - dichloromethane extraction were used to obtain the above fractions from royal jelly. The...