The milk fat globule membrane (MFGM) is a three-layer membrane structure that surrounds milk fat globules. The structure of fat globules in cow milk-based and soy-based infant formulas, lacking MFGM, is quite different from that in human milk. Therefore, addition of exogenous MFGM and preparation...

Glucagon-like peptide-1 (GLP-1) is an important signal in the peripheral and neural systems, which contributes to the maintenance of glucose and energy homeostasis. In this study, ¹H NMR validated polyphenols and polysaccharides extracted from sprouted quinoa yoghurt were used as isolates and...

Previous studies showed that chondrodysplasia has intrauterine origin. Although prenatal acetaminophen exposure (PAcE) can cause nervous and reproductive abnormalities in offspring, its effect on cartilage is uninvestigated. Herein, mice were treated with different doses and courses of...

Objective: To explore the feasibility of new test methods for evaluation of improving hypoxia tolerance function in health food. Methods: Hypoxia tolerance experiments were carried out on mice. The zebrafish hypoxia model was established, and the improvement of zebrafish hypoxia movement and...

Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer that is easily found in the environment. Excessive daily exposure of it may lead to an increased risk of cardiovascular disease (CVD). Lycopene (LYC), as a natural carotenoid, has been shown to have the potential to prevent CVD. However, the...

To investigate the effect of postprandial exercise time on energy and lipid metabolism in type II diabetes, in this study, a type II diabetic rat model was established by a high-fat diet and tail vein injection of 60 mg/kg of streptozotocin. Rats performed treadmill exercise for 30 min (15 m/min)...

Infiltration by adipose tissue macrophages (ATMs) and subsequent metabolic inflammation are the key causes of obesity-induced insulin resistance and metabolic disorders. In this study, we analyzed the potential protective effect of tangeretin, a key flavonoid found extensively in citrus peels,...

Lipid oxidation is the major cause of quality deterioration in freshwater fish, especially mediated by myoglobin (Mb). This study aimed to investigate the antioxidant mechanism of Maillard reaction products (MRPs) in Mb-mediated lipid oxidation in common carp (Cyprinus carpio). MRPs exhibited...

Fat remodeling has been extensively explored through protein deacetylation, but not yet acetylation, as a viable therapeutic approach in the management of obesity and related metabolic disorders. Here, we investigated the functions of key acetyltransferases CBP/p300 in adipose remodeling and their...

Diarrhoea caused by pathogens such as enterotoxigenic E. coli (ETEC) is a serious threat to the health of young animals and human infants. Here, we investigated the protective effect of fructo-oligosaccharides (FOS) on the intestinal epithelium with ETEC challenge in a weaned piglet model....